Navigation Links
Trial launched into curry chemical's cancer-fighting properties
Date:5/6/2012

Compounds found in curry are being investigated as a way of improving drug response in patients with advanced bowel cancer in a new study launched today (Monday).

Scientists at the Cancer Research UK and National Institute for Health Research Experimental Cancer Medicine Centre (ECMC) in Leicester will investigate whether tablets containing curcumin found in the spice turmeric can be safely added to the standard treatment for bowel cancer that has spread.

Earlier studies have shown that curcumin can enhance the ability of chemotherapy to kill bowel cancer cells in the lab.

The trial is being funded by Hope Against Cancer, The Royal College of Surgeons and the Bowel Disease Research Foundation.

Patients with advanced bowel cancer are usually given a treatment called FOLFOX, which combines three chemotherapy drugs. But around 40-60 per cent of patients don't respond and, of those who do, side effects such as severe tingling or nerve pain can limit the number of cycles patients can have.

Chief investigator Professor William Steward, ECMC director at the University of Leicester, said: "Once bowel cancer has spread it is very difficult to treat, partly because the side effects of chemotherapy can limit how long patients can have treatment. The prospect that curcumin might increase the sensitivity of cancer cells to chemotherapy is exciting because it could mean giving lower doses, so patients have fewer side effects and can keep having treatment for longer.

"This research is at a very early stage, but investigating the potential of plant chemicals to treat cancer is an intriguing area that we hope could provide clues to developing new drugs in the future."

Around 40 patients with bowel cancer that has spread to the liver will be recruited to take part in the study at Leicester Royal Infirmary and Leicester General Hospital. Three quarters of these will be given curcumin tablets for seven days, before
'/>"/>

Contact: Ailsa Stevens
44-203-469-8300
University of Leicester
Source:Eurekalert

Page: 1 2

Related biology news :

1. Sentara begins international trial -- open at only 24 US locations
2. 12-month ATLANTA trial data show sustained benefit of Catania Stent
3. First results from hospital trials testing
4. Positive results in Phase 2 trial of treatment of C-difficile-associated diarrhea
5. New filtering technology has environmental, industrial applications
6. Using water to understand human society, from the industrial revolution to global trade
7. First trial in patients with a potential treatment of the incurable ALS muscle disease
8. In just 5 years, gene discovery to clinical trial of potential treatment
9. Vitamins C and E and beta carotene again fail to reduce cancer risk in randomized controlled trial
10. Director of Berman Institute comments on FDA Approval of first human embryonic stem cell trial
11. Review of probiotic trial research finds only Bifantis able to claim efficacy for IBS symptoms
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/1/2015)... , June 1, 2015 ... "Next Generation Biometrics Market by Application (Government, Military ... Travel & Immigration, and Security), Technology (Face Recognition, ... Signature Recognition, Vein Recognition, and Others), Function (Contact ... , Europe , APAC, ...
(Date:5/25/2015)... market for wearable technologies is considered to be in ... several trials and prototypes. The release of the Apple ... interest in wearables as well as accelerate sales of ... in turn will spur greater innovation from other players ... and distributors. Photo - http://photos.prnewswire.com/prnh/20150526/218287 ...
(Date:5/20/2015)... , May 20, 2015 /PRNewswire/ ... http://www.researchandmarkets.com/research/h8t4x6/5year ) has announced the addition ... the Global Iris Recognition Market"  report ... , ,This research service analyses trends ... the government and commercial sectors, globally. ...
Breaking Biology News(10 mins):Next Generation Biometrics Market Worth $24,448.84 Million by 2020 2Next Generation Biometrics Market Worth $24,448.84 Million by 2020 3Next Generation Biometrics Market Worth $24,448.84 Million by 2020 4Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 2Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 3Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 4Global Iris Recognition Market Report 2015 - 5-Year Opportunity Analysis 2
... order animals, genetic information is passed from parents to offspring ... single-celled organisms, such as yeast, the genes can be passed ... major physical changes occur in the genetic material after it ... the production of mature gametes or spores. Near the end ...
... No one has ever seen exactly how water molecules interact ... life . . . that is, not until now. , ... these interactions for the first time, and report the results ... Academy of Sciences. , Proteins are complex molecules that form ...
... cells have a "toggle switch" that enables them to ... and then nest comfortably in their new surroundings, a ... how cancer cells shift between two alternating states -- ... how cancer metastasizes, or spreads to other parts of ...
Cached Biology News:Single molecular 'mark' seen as pivotal for genome compaction in spores and sperm 2Scientists get best look ever at water-life connection 2Newly discovered behavior in cancer cells signals dangerous metastasis 2Newly discovered behavior in cancer cells signals dangerous metastasis 3
(Date:6/1/2015)... , June 1, 2015 ... has announced the addition of the ... Instruments, Services), Test Type (Indirect, Enzyme-based, Reactive ... Cytometry), End Users - Global Forecast to ...      (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ...
(Date:6/1/2015)... , June 1, 2015 /PRNewswire/ - BIOREM Inc. (TSX-V: BRM) ("Biorem" or ... March 31, 2015.  Biorem,s complete 2015 first quarter financial statements and ... Financial Summary:Three-months ended March 31,(in CDN$,000 except per share ... 4,689 , 1,974 Gross profit , 1,531 ... Net earnings (loss) , 528 , (531) Basic ...
(Date:6/1/2015)... -- Research and Markets ( http://www.researchandmarkets.com/research/9kv3rl/global ) has ... Market 2015-2019" report to their offering. ... to grow at a CAGR of 19.49% over ... of science that includes computational analysis of biological ... form and protein sequences in various biological databases. ...
(Date:6/1/2015)... MD (PRWEB) June 01, 2015 ... they have entered into a commercial collaboration agreement ... companies will combine their technologies and work together ... (MSC) regenerative technology. RoosterBio and Sistemic will collaborate ... technologies to build more precise and relevant characterization ...
Breaking Biology Technology:Oxidative Stress Assay Market 2015 - Global Forecast to 2020 2Biorem Reports Increased Revenues and Earnings for First Quarter 2Biorem Reports Increased Revenues and Earnings for First Quarter 3Global Bioinformatics Market 2015-2019 - Rapid Developments in Molecular Diagnostics 2Global Bioinformatics Market 2015-2019 - Rapid Developments in Molecular Diagnostics 3Sistemic and RoosterBio Inc Announce Broad Collaboration Agreement to Advance miRNA and Mesenchymal Stem/Stromal Cell (MSC) Regenerative Technology 2Sistemic and RoosterBio Inc Announce Broad Collaboration Agreement to Advance miRNA and Mesenchymal Stem/Stromal Cell (MSC) Regenerative Technology 3Sistemic and RoosterBio Inc Announce Broad Collaboration Agreement to Advance miRNA and Mesenchymal Stem/Stromal Cell (MSC) Regenerative Technology 4
... computer has those moments when things go wrong and then ... system feature, a difficult level in a video game or ... annoyed, angry and frustrated and then realizes how to ... the computer feel and act the same way? , ,A ...
... the USDA Forest Service Forest Products Laboratory (FPL) have ... paper industry in an effort to reduce the economic ... in business and government offices while simultaneously ... buys some 500,000 tons of bleached kraft paper, which ...
... Madison, Wis. - The Wisconsin Alumni Research ... information technology firm IBM over charges of ... IBM of infringing on patented technology by marketing and ... based on WARF's technology. A trial was scheduled for ...
Cached Biology Technology:Why can't your computer get frustrated, too? 2Why can't your computer get frustrated, too? 3Why can't your computer get frustrated, too? 4Reducing brightness to make a better paper 2Reducing brightness to make a better paper 3WARF settles patent dispute with IBM 2
Ready for formulation or direct injection into animals Provided in convenient 100, 250, 1000 and 10,000 nmol sizes HPLC purified, salt free, sterile filtered, and endotoxin tested ...
... custom siRNA service provides the premium quality ... research. Custom siRNAs can be readily ordered ... target sequence, or by providing the sense ... Ambion's Silencer Validated and ...
GEL FILTRATION CAL KIT HMW, 1 EA. *Category: Gel Filtration Gels....
Mouse monoclonal [6C3] to JAB1 ( Abpromise for all tested applications). entrezGeneID: 10987 SwissProtID: O15386...
Biology Products: