Navigation Links
Trial aims to advance prenatal diagnosis of genetic defects
Date:8/21/2013

NEW YORK (August 21, 2013) Reproductive genetics researchers at Columbia University Medical Center (CUMC) are leading a multicenter prospective clinical study investigating the effects of chromosomal abnormalities (duplicative or missing material) found prenatally through microarray analysis. The goal of the study is to gain further information on genetic variances previously not well reported in the medical literature and share it with parents during pregnancy.

Led by principal investigator Ronald J. Wapner, MD, professor and vice chair for research at CUMC's Department of Obstetrics and Gynecology and director of reproductive genetics at NewYork-Presbyterian Hospital/Columbia, the research is the next phase of a project to advance clinicians' ability to diagnose in utero conditions such as developmental delays, structural abnormalities, and treatable or life-threatening diseases.

"Parents of children found to have a genetic variance want a better understanding of what it means. Our goal is to give them as much information and support as possiblefrom detailed genetic counseling to ways to connect with other people expecting children with the same variance," said Dr. Wapner.

In December 2012, Dr. Wapner and colleagues published in the New England Journal of Medicine (NEJM) findings of a trial involving 4,400 patients at 29 centers nationwide. That study showed that microarray analysis of a fetus's DNA gave significantly more clinically relevant information than the standard method of analysis, known as karyotypinga visual analysis of the fetus's chromosomes. [Click here for a news release about that study.]

In the current studywhich has ongoing clinical recruitmentdata on babies included in the NEJM article will be augmented by data on patients recruited by 10 major prenatal diagnostic centers around the country that offer microarray to all their patients. Each center aims to recruit 1,000 patients. Of the anticipated 10,00
'/>"/>

Contact: Elizabeth Streich
eas2125@cumc.columbia.edu
212-305-3689
Columbia University Medical Center
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Ultrasound patch heals venous ulcers in human trial
2. UCLA stem cell gene therapy for sickle cell disease advances toward clinical trials
3. New sickle cell anemia therapy advances to Phase II clinical trials
4. Alios BioPharma initiates Phase 1 clinical trial for respiratory syncytial virus infection
5. Intermountain Medical Center reseachers develop new 3-D technology to treat atrial fibrillation
6. Elseviers Maturitas publishes clinical guide on endometrial assessment in postmenopausal women
7. Ecology, economy and management of an agro-industrial Amazon frontier
8. FDA approves Phase II of stem cell trial for ALS led by U-Ms Dr. Eva Feldman
9. A trial to find out the effectiveness of biocides against Vespa velutina
10. Sea level rise: Jeopardy for terrestrial biodiversity on islands
11. Mummy CT scans show preindustrial hunter gatherers had clogged arteries
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/31/2015)... March 31, 2015  Elephant Talk Communications Corp. (NYSE ... provider of Software Defined Network Architecture (ET Software DNA® ... revenue of approximately $20.4 million for the year ended ... million for the year ended December 31, 2013. ... Company had completed its multi-year transition away from its ...
(Date:3/24/2015)... DUBLIN , Mar. 24, 2015 Research and ... addition of the "Global Iris Recognition Market 2015-2019" ... forecast the Global Iris Recognition market to grow at ... This report covers the present scenario and ... for the period 2015-2019. To calculate the market size, ...
(Date:3/23/2015)... 23, 2015 SoundView Technology Group issues a new ... NXTD ) Wocket smart wallet. SoundView was one of the selected ... experience with the Wocket in multiple scenarios and outlets. ... and other retailers, making both debit and credit card payments.  ... says, "If the company meets their plans in 2015, it ...
Breaking Biology News(10 mins):Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 3Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 4Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 5Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 6Global Iris Recognition Market 2015-2019 with 3M Cogent, Bioenable Technologies, Cross Match Technology, Iris ID Systems & Safran Dominating 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 3Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 4
... Sandata Technologies, Inc., a leading nationwide provider ... and social services communities, today announced an agreement ... in software, services, information, and connectivity solutions for ... preferred electronic time and attendance provider for current ...
... Bioscientists are transferring GM knowledge and technology from the ... food insecurity in Sub-Saharan Africa. Professor Howard Atkinson (University ... for the first time at a landmark meeting at ... 100 African speakers and delegates. The project aims to ...
... new genome-wide association study published today in Nature ... variations in eight blood measurements and the impact those ... including the number and volume of cells in the ... of disorders, including anaemia, infection and blood cell cancers. ...
Cached Biology News:Allscripts and Sandata Partner to Enhance Quality in Home Care Agencies Nationwide 2Allscripts and Sandata Partner to Enhance Quality in Home Care Agencies Nationwide 3Blood counts are clues to human disease 2Blood counts are clues to human disease 3
(Date:5/5/2015)... May 05, 2015 The Academy of ... of Indiana, led by Indiana Gov. Mike Pence, has ... AMA Foundation will host a Family Fest and aviation ... proceeds will benefit the Wounded Warrior Project. , National ... of Model Aeronautics—the country’s foremost organization for model aviation—to ...
(Date:5/5/2015)... -- A group of biotechnology executives and medical doctors announced ... non-profit organization dedicated to providing education, research and therapeutic ... consciousness.  ... Coma is the ... actions can be initiated by the patient, and sleep-wake ...
(Date:5/5/2015)... , May 05, 2015 Research and ... the addition of the "Clinical Laboratory, Molecular ... Forecasts 2015 to 2019 - Europe Version" ... developments especially in the area of molecular diagnostics ... growing and evolving world market that is moving ...
(Date:5/5/2015)... MI (PRWEB) May 05, 2015 ... Parker Hannifin distributor, announces the launch of ... fleet operators with a convenient way to purchase ... maintenance products . , The new website ... 100,000 vehicles with direct access to high performance ...
Breaking Biology Technology:State of Indiana proclaims August 15 as Model Aviation Day 2Biotechnology Executives and Medical Doctors Team Up to Tackle Coma and Disorders of Consciousness 2Biotechnology Executives and Medical Doctors Team Up to Tackle Coma and Disorders of Consciousness 3Biotechnology Executives and Medical Doctors Team Up to Tackle Coma and Disorders of Consciousness 4Biotechnology Executives and Medical Doctors Team Up to Tackle Coma and Disorders of Consciousness 5European Clinical Laboratory, Molecular Diagnostics and Genomic Testing Services Market 2015-2019 2Exotic Automation & Supply Launches Ecommerce Website 2
... The Gerresheimer,Group today opened a new plant ... production facility constructed in Danyang (Jiangsu Province),covers ... and cartridges for injection systems it serves ... a local and international level. Dr. Axel ...
... MISSISSAUGA, ON, May 28 /PRNewswire-FirstCall/ - YM BioSciences ... an oncology company that identifies, develops and commercializes ... a poster presentation will report results from a ... with head and neck cancer conducted by Biocon ...
... patient was supported with the,Berlin Heart EXCOR(R) Pediatric Ventricular ... first implantation of the device in 1990. The,patient, an ... in Chicago and has been successfully transplanted in the ... diagnosed a few weeks after birth with left,ventricular non ...
Cached Biology Technology:Gerresheimer Opens New High-Tech Production Facility for Pharma Glass in China 2Gerresheimer Opens New High-Tech Production Facility for Pharma Glass in China 3YM BIOSCIENCES ANNOUNCES RESULTS OF RANDOMIZED NIMOTUZUMAB STUDY TO BE PRESENTED IN A POSTER AT ASCO ANNUAL MEETING 2YM BIOSCIENCES ANNOUNCES RESULTS OF RANDOMIZED NIMOTUZUMAB STUDY TO BE PRESENTED IN A POSTER AT ASCO ANNUAL MEETING 3500th Patient Receives Berlin Heart EXCOR Pediatric Ventricular Assist Device 2
... Shaker provides the exact agitation needed ... very slow to fast speed and ... a gentle wave motion that lifts ... membranes to achieve faster, more uniform ...
... slide in this set of Antibody ... triplicate, for a total of over ... as internal control. Antibodies belonging to ... apoptosis, cell cycle progression, signal transduction ...
...
Practical tool for easy, effective sealing of 0.2ml PCR tubes and plates using cap strips....
Biology Products: