Navigation Links
Treadmill step training promotes motor function after incomplete spinal cord injury

A large body of evidence shows that spinal circuits are significantly affected by training, and that intrinsic circuits that drive locomotor tasks are located in lumbosacral spinal segments in rats with complete spinal cord transection. However, after incomplete lesions, the effect of treadmill training has been debated, which is likely because of the difficulty of separating spontaneous stepping from specific training-induced effects. According to a study published in the Neural Regeneration Research (Vol. 8, No. 27, 2013), a rat model of spinal cord contusion at the T10 level was used to examine the effect of step training. After 3 weeks of step training, the rats with spinal cord contusion at the T10 level exhibited a significantly greater improvement in the Basso, Beattie and Bresnahan score. The expression of growth-associated protein-43 in the spinal cord lesion site and the number of tyrosine hydroxylase-positive ventral neurons in the second lumbar spinal segment were greater at 11 weeks post-injury, while the levels of brain-derived neurotrophic factor protein in the spinal cord lesion site showed no changes. These results suggest that treadmill training substantially improved spontaneous motor activity in rats with incomplete spinal cord injury. The improvement in rat behavior was associated with a significant increase in growth-associated protein-43 expression in the injured spinal cord and in tyrosine hydroxylase expression in the second lumbar spinal segment. Treadmill training significantly improves functional recovery and neural plasticity after incomplete spinal cord injury.


Contact: Meng Zhao
Neural Regeneration Research

Page: 1

Related biology news :

1. Training the future biomanufacturing workforce
2. European support for the first network of research and training in political ecology
3. Academy scientists receive top honors for long-term research and training initiatives in Mongolia
4. Intensive training for aphasia: Even older patients can improve
5. Strength training improves vascular function in young black men
6. OU research groups awarded NSF grants to expand research and training in science and engineering
7. Brain training may lessen cognitive impairments associated with coronary bypass surgery
8. NIBIB and HHMI announce graduate biomedical training awards
9. Swim training plus healthy diet factor in cancer fight: New study
10. Training cells to perform Boolean functions? Its logical
11. NJIT, Chinas Bengbu Glass Institute sign agreement for R&D, training
Post Your Comments:
Related Image:
Treadmill step training promotes motor function after incomplete spinal cord injury
(Date:10/29/2015)... , Oct. 29, 2015 Daon, a ... that it has released a new version of its ... in North America have already ... v4.0 also includes a FIDO UAF certified server ... already preparing to activate FIDO features. These customers include ...
(Date:10/27/2015)... , Oct. 27, 2015 In the present ... of concern for various industry verticals such as banking, ... to the growing demand for secure & simplified access ... ,sectors, such as hacking of bank accounts, misuse of ... equipment such as PC,s, laptops, and smartphones are expected ...
(Date:10/26/2015)... , Oct. 26, 2015  Delta ID Inc., ... authentication to mobile and PC devices, announced its ActiveIRIS® ... the arrows NX F-02H launched by NTT DOCOMO, INC ... F-02H is the second smartphone to include iris recognition ... in ARROWS NX F-04G in May 2015, world,s first ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... --> --> ... Synthesis Market by Product & Services (Primer, Probe, Custom ... RNAi), End-User (Research, Pharmaceutical & Biotech, Diagnostic Labs) - ... is expected to reach USD 1,918.6 Million by 2020 ... of 10.1% during the forecast period. Browse ...
(Date:11/24/2015)... ALBANY, New York , November 24, 2015 /PRNewswire/ ... According to a recent market research report released by ... is projected to expand at a CAGR of 17.5% ... titled "Non-invasive Prenatal Testing Market - Global Industry Analysis, ... 2022", estimates the global non-invasive prenatal testing market to ...
(Date:11/24/2015)... Urdorf, Switzerland (PRWEB) , ... November 24, 2015 ... ... the plant and the environment are paramount. Insertion points for in-line sensors can ... TOLEDO has developed the InTrac 781/784 series of retractable sensor housings , ...
(Date:11/24/2015)... ANGELES , Nov. 24, 2015 ... biotechnology company focused on the discovery, development and commercialization ... , Ph.D., Chief Executive Officer, is scheduled to present ... 1, 2015 at 10:50 a.m. EST, at The Lotte ... City . . ...
Breaking Biology Technology: