Navigation Links
Treadmill step training promotes motor function after incomplete spinal cord injury
Date:11/5/2013

A large body of evidence shows that spinal circuits are significantly affected by training, and that intrinsic circuits that drive locomotor tasks are located in lumbosacral spinal segments in rats with complete spinal cord transection. However, after incomplete lesions, the effect of treadmill training has been debated, which is likely because of the difficulty of separating spontaneous stepping from specific training-induced effects. According to a study published in the Neural Regeneration Research (Vol. 8, No. 27, 2013), a rat model of spinal cord contusion at the T10 level was used to examine the effect of step training. After 3 weeks of step training, the rats with spinal cord contusion at the T10 level exhibited a significantly greater improvement in the Basso, Beattie and Bresnahan score. The expression of growth-associated protein-43 in the spinal cord lesion site and the number of tyrosine hydroxylase-positive ventral neurons in the second lumbar spinal segment were greater at 11 weeks post-injury, while the levels of brain-derived neurotrophic factor protein in the spinal cord lesion site showed no changes. These results suggest that treadmill training substantially improved spontaneous motor activity in rats with incomplete spinal cord injury. The improvement in rat behavior was associated with a significant increase in growth-associated protein-43 expression in the injured spinal cord and in tyrosine hydroxylase expression in the second lumbar spinal segment. Treadmill training significantly improves functional recovery and neural plasticity after incomplete spinal cord injury.


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert  

Page: 1

Related biology news :

1. Training the future biomanufacturing workforce
2. European support for the first network of research and training in political ecology
3. Academy scientists receive top honors for long-term research and training initiatives in Mongolia
4. Intensive training for aphasia: Even older patients can improve
5. Strength training improves vascular function in young black men
6. OU research groups awarded NSF grants to expand research and training in science and engineering
7. Brain training may lessen cognitive impairments associated with coronary bypass surgery
8. NIBIB and HHMI announce graduate biomedical training awards
9. Swim training plus healthy diet factor in cancer fight: New study
10. Training cells to perform Boolean functions? Its logical
11. NJIT, Chinas Bengbu Glass Institute sign agreement for R&D, training
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Treadmill step training promotes motor function after incomplete spinal cord injury
(Date:12/6/2016)... Biomet Holdings, Inc. (NYSE and SIX: ZBH) (the "Company") today ... principal amount of its 1.414% senior unsecured notes due 2022 ... notes due 2026. The closing of the ... the satisfaction of customary closing conditions.  The notes will pay ... The Company intends to use the net proceeds from the ...
(Date:12/2/2016)... AUSTIN, Texas , Dec. 1, 2016 /PRNewswire/ ... provider, today announced BioLock , an electrocardiogram ... and health monitoring, a key IoT asset. The ... embedded into a vehicle,s steering wheel and mobile ... a simple touch. As vehicle technology ...
(Date:11/29/2016)... Nearly one billion matches per second with DERMALOG,s high-speed AFIS    ... ... DERMALOG is Germany's largest Multi-Biometric supplier: The company's Fingerprint ... ... Multi-Biometric supplier: The company's Fingerprint Identification System is part of an efficient ...
Breaking Biology News(10 mins):
(Date:12/8/2016)... ... December 08, 2016 , ... Microbial ... Technology Awards. uBiome is one of just six company finalists in the Health ... addition to uBiome, companies nominated as finalists in this year’s awards include Google, ...
(Date:12/8/2016)... Savannah River Remediation LLC group evaluated ... NT-MAX Lake & Pond Sludge and Muck ... conjunction with Hexa Armor/ Rhombo cover manufactured by ... Discharge Elimination System requirements. The Savannah ... of elevated pH levels, above 8.5, especially during ...
(Date:12/7/2016)... ... December 07, 2016 , ... A new study published in ... previously treated, advanced pancreatic cancer, liquid biopsies are not yet an adequate substitute ... of blood sampling may improve the value of a blood-based test.” The study ...
(Date:12/7/2016)... 2016  Nordion, a standalone business of Sterigenics ... today,s award by the United States Department of ... the Phase II cooperative agreement funding to GA ... University of Missouri Research Reactor Center (MURR ® ... establishment of a new, reliable supply of molybdenum ...
Breaking Biology Technology: