Navigation Links
Treadmill step training promotes motor function after incomplete spinal cord injury
Date:11/5/2013

A large body of evidence shows that spinal circuits are significantly affected by training, and that intrinsic circuits that drive locomotor tasks are located in lumbosacral spinal segments in rats with complete spinal cord transection. However, after incomplete lesions, the effect of treadmill training has been debated, which is likely because of the difficulty of separating spontaneous stepping from specific training-induced effects. According to a study published in the Neural Regeneration Research (Vol. 8, No. 27, 2013), a rat model of spinal cord contusion at the T10 level was used to examine the effect of step training. After 3 weeks of step training, the rats with spinal cord contusion at the T10 level exhibited a significantly greater improvement in the Basso, Beattie and Bresnahan score. The expression of growth-associated protein-43 in the spinal cord lesion site and the number of tyrosine hydroxylase-positive ventral neurons in the second lumbar spinal segment were greater at 11 weeks post-injury, while the levels of brain-derived neurotrophic factor protein in the spinal cord lesion site showed no changes. These results suggest that treadmill training substantially improved spontaneous motor activity in rats with incomplete spinal cord injury. The improvement in rat behavior was associated with a significant increase in growth-associated protein-43 expression in the injured spinal cord and in tyrosine hydroxylase expression in the second lumbar spinal segment. Treadmill training significantly improves functional recovery and neural plasticity after incomplete spinal cord injury.


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert  

Page: 1

Related biology news :

1. Training the future biomanufacturing workforce
2. European support for the first network of research and training in political ecology
3. Academy scientists receive top honors for long-term research and training initiatives in Mongolia
4. Intensive training for aphasia: Even older patients can improve
5. Strength training improves vascular function in young black men
6. OU research groups awarded NSF grants to expand research and training in science and engineering
7. Brain training may lessen cognitive impairments associated with coronary bypass surgery
8. NIBIB and HHMI announce graduate biomedical training awards
9. Swim training plus healthy diet factor in cancer fight: New study
10. Training cells to perform Boolean functions? Its logical
11. NJIT, Chinas Bengbu Glass Institute sign agreement for R&D, training
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Treadmill step training promotes motor function after incomplete spinal cord injury
(Date:11/15/2018)... ... November 14, 2018 , ... Researchers at the ... up the analysis and publication of biomedical data from many months or years ... now, the primary method available to share biomedical research data has been through ...
(Date:11/14/2018)... ... 2018 , ... In recognition of World Diabetes Day, Diopsys is lending its ... company is reaching out to help educate patients and the healthcare community about the ... testing for people with the disease. , The American Diabetes Association (ADA) released ...
(Date:11/13/2018)... ... November 13, 2018 , ... Fluence ... controlled-environment cultivation applications. VYPR 2 is well suited for sole-source and supplemental lighting ... growing markets. , “As an all-purpose light which can be adapted to ...
Breaking Biology News(10 mins):
(Date:10/31/2018)... Calif. (PRWEB) , ... October 30, 2018 , ... Pippa Rose is a young Labrador ... around one year old, Pippa suffered a partial tear to the cruciate ligament in her ... to run or go on walks. Kinsley reported that it broke her heart to ...
(Date:10/29/2018)... ... October 29, 2018 , ... PracticeMatch , a company that provides the ... physician career fairs planned for 2019. The company has expanded its offering of virtual ... the areas of the country which have the highest concentrations of resident and fellow ...
(Date:10/24/2018)... , ... October 22, 2018 , ... ... Philip Bourne, PhD, Director of the Data Science Institute, Stephenson Chair of Data ... Scientific Advisory Board. Joining the board of leading scientists and doctors from around ...
(Date:10/18/2018)... ... October 18, 2018 , ... R3 Stem Cell is ... day regenerative therapy training workshop. The discount is good through November 7th, 2018, with ... stem cell and PRP training workshop includes an amazing useful array of hands on ...
Breaking Biology Technology: