Navigation Links
Treadmill step training promotes motor function after incomplete spinal cord injury
Date:11/5/2013

A large body of evidence shows that spinal circuits are significantly affected by training, and that intrinsic circuits that drive locomotor tasks are located in lumbosacral spinal segments in rats with complete spinal cord transection. However, after incomplete lesions, the effect of treadmill training has been debated, which is likely because of the difficulty of separating spontaneous stepping from specific training-induced effects. According to a study published in the Neural Regeneration Research (Vol. 8, No. 27, 2013), a rat model of spinal cord contusion at the T10 level was used to examine the effect of step training. After 3 weeks of step training, the rats with spinal cord contusion at the T10 level exhibited a significantly greater improvement in the Basso, Beattie and Bresnahan score. The expression of growth-associated protein-43 in the spinal cord lesion site and the number of tyrosine hydroxylase-positive ventral neurons in the second lumbar spinal segment were greater at 11 weeks post-injury, while the levels of brain-derived neurotrophic factor protein in the spinal cord lesion site showed no changes. These results suggest that treadmill training substantially improved spontaneous motor activity in rats with incomplete spinal cord injury. The improvement in rat behavior was associated with a significant increase in growth-associated protein-43 expression in the injured spinal cord and in tyrosine hydroxylase expression in the second lumbar spinal segment. Treadmill training significantly improves functional recovery and neural plasticity after incomplete spinal cord injury.


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert  

Page: 1

Related biology news :

1. Training the future biomanufacturing workforce
2. European support for the first network of research and training in political ecology
3. Academy scientists receive top honors for long-term research and training initiatives in Mongolia
4. Intensive training for aphasia: Even older patients can improve
5. Strength training improves vascular function in young black men
6. OU research groups awarded NSF grants to expand research and training in science and engineering
7. Brain training may lessen cognitive impairments associated with coronary bypass surgery
8. NIBIB and HHMI announce graduate biomedical training awards
9. Swim training plus healthy diet factor in cancer fight: New study
10. Training cells to perform Boolean functions? Its logical
11. NJIT, Chinas Bengbu Glass Institute sign agreement for R&D, training
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Treadmill step training promotes motor function after incomplete spinal cord injury
(Date:5/24/2016)... 2016 Ampronix facilitates superior patient care by providing unparalleled technology to leaders ... is the latest premium product recently added to the range of products distributed by ... ... ... LCD Medical Display- Ampronix News ...
(Date:5/20/2016)... May 20, 2016  VoiceIt is excited to ... VoicePass. By working together, VoiceIt and ... VoiceIt and VoicePass take slightly different approaches to ... both security and usability. ... this new partnership. "This marketing and ...
(Date:5/16/2016)... May 16, 2016   EyeLock LLC , a ... the opening of an IoT Center of Excellence in ... expand the development of embedded iris biometric applications. ... of convenience and security with unmatched biometric accuracy, making ... aside from DNA. EyeLock,s platform uses video technology to ...
Breaking Biology News(10 mins):
(Date:5/26/2016)... ... May 26, 2016 , ... ... today announced several positive developments that position the Company for the future. ... the transaction, Craig F. Kinghorn has been appointed Chairman of the Board, Curtis ...
(Date:5/26/2016)... ... May 26, 2016 , ... FireflySci has been manufacturing ... laboratories all over the globe. Their cute firefly logo has been spreading to ... FireflySci makes spectrophotometer calibration standards that never require recalibration. These revolutionary standards ...
(Date:5/25/2016)... San Diego, Calif. (PRWEB) , ... May 25, 2016 , ... ... San Diego area and has consistently been rated one of its top attractions. ... over the globe to participate in a unique and intimate team-building experience. , Each ...
(Date:5/25/2016)... ... 2016 , ... Thailand’s Board of Investment’s New York office, ... Located at booth number 7301, representatives from the Thai Government, research organizations, and ... biotechnology and life sciences sector. , Deputy Secretary General of the Thailand ...
Breaking Biology Technology: