Navigation Links
Transplanted stem cells help prevent bladder fibrosis after spinal cord injury
Date:9/3/2014

e treatment group received the B10 cells transplanted directly into the bladder wall. To track the transplanted B10 cells via magnetic resonance imaging (MRI), the researchers labeled them with fluorescent magnetic particles.

"HGF plays an essential role in tissue regeneration and angiogenesis and acts as a potent antifibrotic agent," explained Kim.

The researchers concluded that local injection, rather than systemic intravenous injection, was preferred because systemic injection caused the hMSCs to be localized in the pulmonary capillary bed.

Voiding function was assessed at four weeks post-transplantation and MRI "showed clear hypointense signal induced by the labeled cells". When the bladders of the transplanted group were harvested they were found to have improved smooth muscle cells and reduced collagen deposition.

The researchers concluded that MSC-based cell transplantation may be a novel therapeutic strategy for bladder dysfunction in patients with SCI.

"This study provides potential evidence that an human stable immortalized MSC line could be useful in the treatment of spinal cord injury-related problems such as bladder dysfunction." said Dr. David Eve, associate editor of Cell Transplantation and Instructor at the Center of Excellence for Aging & Brain Repair at the University of South Florida. "Further studies to elucidate the mechanisms of action and the long term effects of the cells, as well as confirm the optimal route of administration, will help to illuminate what the true benefit of these cells could be."


'/>"/>

Contact: Robert Miranda
cogcomm@aol.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

Page: 1 2

Related biology news :

1. Interleukin-10 aids survival of cells transplanted to repair cardiac tissues after MI
2. Zhichan decoction increases dopaminergic neurons from transplanted NSCs in PD
3. Study finds long-term survival of human neural stem cells transplanted into primate brain
4. Transplanted human umbilical cord blood cells improved heart function in rat model of MI
5. Co-transplanted cells and treadmill training aids rats with spinal cord injury
6. Type 2 diabetes patients transplanted with own bone marrow stem cells reduces insulin use
7. Transplanted genetically-modified adipose cells offer potential therapy for liver diseases
8. Cell Transplantation study investigates fate and function of cells transplanted to the CNS
9. Transplanted neural stem cells slows als onset and progression in mouse models
10. Sabotage as therapy: Aiming lupus antibodies at vulnerable cancer cells
11. Scripps Florida scientists make diseased cells synthesize their own drug
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... NEW YORK , Nov. 19, 2014  Earlier ... Board at New York College, and one of the ... for biosensor signals that are transmitted from Smartphones to ... there were Smartphones and has one of the earliest ... are discussing its usage in the military, child care, ...
(Date:11/18/2014)... , Nov. 18, 2014  The Secure ... Industry Association today jointly announce the formation of ... release of its Identity and Biometric Entry ... The Framework received official support from BORDERPOL, the ... to improve and provide expertise regarding border security, ...
(Date:11/15/2014)... YORK , Nov. 13, 2014  While we may ... technology Doctor McCoy used in "Star Trek" to gain instant ... tools designed to work with smartphones and tablets for monitoring ... of the healthcare world. This may seem a tad Orwellian ... ready to adopt some of these technological opportunities into their ...
Breaking Biology News(10 mins):Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 4Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3Americans May Be Ready for a Brave New World of Healthcare 2Americans May Be Ready for a Brave New World of Healthcare 3Americans May Be Ready for a Brave New World of Healthcare 4
... 3 issue of Nature, Johns Hopkins researchers report that ... come together to turn the liver into a sugar-producing ... of sugar is a damaging problem in people with ... future drugs to fight the disease, the researchers say. ...
... Mayo Clinic researchers and conducted by the North Central Cancer ... for an incurable form of recurrent brain cancer slowed tumor ... who tried it. The same research team also developed a ... to this treatment. , Mayo researchers will present these findings ...
... by camouflage in the same way that humans are deceived, ... idea that bold contrasting colours help to break-up the body's ... as the First World War. And in biology this idea ... insects such as moths conceal themselves from predators, shaping the ...
Cached Biology News:Computational verification of protein-protein interactions by orthologous co-expression 2Computational verification of protein-protein interactions by orthologous co-expression 3'Smart drug' targets deadly brain cancer 2'Smart drug' targets deadly brain cancer 3
(Date:11/26/2014)... Bioscience, Inc. (NASDAQ: ROKA ), a molecular diagnostics ... of foodborne pathogens, today announced that Paul G. Thomas ... Annual Healthcare Conference on December 2, 2014 at 4:30pm ET. ... in New York, NY . ... operations, strategies and prospects may be discussed. To listen to ...
(Date:11/24/2014)...   First published articles now ... Elsevier , a world-leading provider of scientific, technical and medical ... of the latest title in the Current Opinion journal ... . Current Opinion in ... to keep up-to-date with the expanding volume of information published ...
(Date:11/24/2014)... November 24, 2014 The new ... from METTLER TOLEDO demonstrates how to reduce the ... analytics and sample panel design can be complicated, ... and protect against corrosion and deposition. Dedicated single ... significant amount of panel space. Additionally, installing and ...
(Date:11/22/2014)... 21, 2014 During his lifetime Richard ... need to surround himself with great people and take ... his friends often marveled at his extraordinarily courageous attitude ... life and -- even with his death impending—that’s how ... disease that would ultimately take his life. , Carrying ...
Breaking Biology Technology:Roka Bioscience to Present at the Piper Jaffray Healthcare Conference 2Elsevier Announces Launch of New Journal: Current Opinion in Food Science 2Elsevier Announces Launch of New Journal: Current Opinion in Food Science 3New Video Shows How to Simplify Cycle Chemistry Sample Panels to Save Time and Costs 2Sherry Sharp, Wife of CarMax Founder, Richard Sharp, Accepts Seat on Board of Cure Alzheimer’s Fund 2Sherry Sharp, Wife of CarMax Founder, Richard Sharp, Accepts Seat on Board of Cure Alzheimer’s Fund 3
... ... Spectrum Chemicals & Laboratory Products (Spectrum) announced the distribution launch ... productivity and lessen injuries due to repetitive hand crimping. ... engineered to improve throughput in laboratories performing chromatography, analytical testing, ...
... , , FRAZER, Pa., Aug. ... that it has completed its previously announced acquisition of all of ... As a result of the acquisition, Arana is now a ... and CEO, Frank Baldino Jr., Ph.D., said, "We are excited about ...
... BEIJING, Aug. 10 /PRNewswire-Asia-FirstCall/ -- Yongye International, Inc.,(OTC ... developer and,distributor of Shengmingsu branded plant and animal nutrient ... that the Company expanded,its research and development center in ... greenhouses and an open testing field. , ...
Cached Biology Technology:Spectrum Announces New Distribution of AC-Powered Tool for Crimping and Decapping of Laboratory Vials - The CRIMPenstein™ 2Cephalon Completes Acquisition of Arana Therapeutics 2Cephalon Completes Acquisition of Arana Therapeutics 3Yongye International Announces Expansion of Research and Development Center 2Yongye International Announces Expansion of Research and Development Center 3
... Immunogen: Synthetic peptide derived from the C ... protein This peptide sequence is downstream ... Zymed polyclonal Connexin 36 antibody Cat. No. ... 36. Reactivity: Mouse (positive control: mouse ...
...
...
...
Biology Products: