Navigation Links
Transient receptor potential channel A1 may contribute to hyperalgesia
Date:12/23/2013

Transient receptor potential channel A1 is one of the important transducers of noxious stimuli in the primary afferents, which may contribute to generation of neurogenic inflammation and hyperalgesia. However, there is no direct evidence that activation of transient receptor potential channel A1 contributes to neuropeptide release from primary afferent neurons. A recent study by Yi Dai and team from Hyogo College of Medicine in Japan demonstrated for the first time that allyl isothiocyanate (AITC; also known as mustard oil) activates transient receptor potential channel A1, resulting in calcitonin gene-related peptide release from the cultured rat dorsal root ganglion neurons. Knockdown of transient receptor potential channel A1 with an antisense oligodeoxynucleotide prevented calcitonin gene-related peptide release by allyl isothiocyanate application in cultured dorsal root ganglion neurons. Thus, the researchers concluded that transient receptor potential channel A1 activation caused calcitonin gene-related peptide release in sensory neurons. These findings were published in the Neural Regeneration Research (Vol. 8, No. 32, 2013).


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert  

Page: 1

Related biology news :

1. Stanford and Google team up to simulate key drug receptor
2. Extensive variability in olfactory receptors influences human odor perception
3. Researchers use nanoscale patches to sensitize targeted cell receptors
4. New book on Signaling by Receptor Tyrosine Kinases by Cold Spring Harbor Laboratory Press
5. Dysfunctional chemokine receptor promotes candidiasis
6. Baculovirus-recognizing human cell receptor identified for the first time
7. Blocking overactive receptor in Alzheimers recovers memory loss and more
8. OHSU scientists advance understanding of brain receptor; may help fight neurological disorders
9. Genetic and clinical factors best to predict late recurrence in estrogen receptor POS breast cancer
10. Therapies for ALL and AML targeting MER receptor hold promise of more effect with less side-effect
11. Activation of cortical type 2 cannabinoid receptors ameliorates ischemic brain injury
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Transient receptor potential channel A1 may contribute to hyperalgesia
(Date:12/17/2014)... , Dec. 16, 2014 Research and ... the addition of the "Global Chemical Sensor ... http://photos.prnewswire.com/prnh/20130307/600769 ... the increasing demand for medical sensors in biomedical ... data for quick and correct diagnosis during surgical ...
(Date:12/11/2014)... 09, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has announced the addition ... Region 2015-2019"  report to their offering. ... is advances in technology. With continuous advances in ... to the latest standard that meets the needs ...
(Date:12/11/2014)... 2014  Data Sciences International (DSI), the global ... new series of digital telemetry implants to meet ... series, part of the PhysioTel™ Digital platform, was ... physiologic data when incorporating functional endpoints into repeat-dose ... toxicology studies has evolved from short ECG strips ...
Breaking Biology News(10 mins):Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2New telemetry implants expected to change how large animal toxicology studies are conducted 2
... news release is available in German . ... remembering painful lessons in German or Latin grammar in school. Languages ... correctly makes the difference between something which "sounds good", and something ... have shown that sensitivity to very simple structural and melodic patterns ...
... list that was established by the EU Scientific ... European young investigators network for Usher syndrome (EUR-USH) ... University Mainz for funding. Out of 82 submitted ... projects that were chosen after a competitive two-step ...
... they have found ,missing heat, in the climate system, casting ... over the past decade. , Observational data on which ... the planet with Polar regions and parts of Africa ... the University of York, and Robert Way, a cryosphere specialist ...
Cached Biology News:Monkeys 'understand' rules underlying language musicality 2European young investigators network for Usher syndrome awarded E-Rare collab project 2'Missing heat' discovery prompts new estimate of global warming 2
(Date:12/22/2014)... CHAPEL HILL, N.C. , Dec. 22, 2014 ... ALNE) today announced that it has signed a ... biotechnology company that has developed and patented a ... and medical diagnostics products that enable rapid on-site ... and alcohol use/abuse and health issues in an ...
(Date:12/22/2014)... The American Journal of Hematology/Oncology, a ... editorials addressing developments and pathways related to oncological ... article exploring the role of follicle-stimulating hormone (FSH) ... prostate cancer. , The article references seminal ... there could be a connection to prostate cancer ...
(Date:12/19/2014)... Hershey, PA (PRWEB) December 19, 2014 ... a leading developer and manufacturer of needle-free injection ... an agreement with Immunomic Therapeutics, Inc. (“ITI”) for ... injection device with its LAMP™ vaccine platform. ... for an exclusive Worldwide license to the Biojector®-2000 ...
(Date:12/19/2014)... 2014 Naurex Inc., a biopharmaceutical company leveraging ... of the central nervous system, today announced that ... will present at the 33 rd annual J.P. ... at 3:00 p.m. PST on Tuesday, January 13, 2015, ... Francisco, Calif. About Naurex ...
Breaking Biology Technology:ALNE Announces Intention To Acquire BioTechPharma 2Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 2Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 3Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 4Bioject and Immunomic Therapeutics Enter into an Agreement for License of Needle-Free Technology for LAMP-vax Vaccines 2Bioject and Immunomic Therapeutics Enter into an Agreement for License of Needle-Free Technology for LAMP-vax Vaccines 3Naurex to Present at 33rd Annual J.P. Morgan Healthcare Conference 2
... and the University of Puerto Rico have granted an ... that can be designed to emit light in any ... Performance Indicator, LLC, of Lowell, Mass., acquired the ... energy absorbed by a substance is released relatively slowly ...
... , STOCKHOLM, Aug. 17 ... Representative Diana DeGette (D. Colo) will be a keynote speaker at ... 2009. Ms. DeGette, co-sponsor of the pioneering Stem Cell Research ... healthcare reform, will help open SALSS, a vital showcase for the ...
... , , ... a biotechnology company developing antiviral therapies with a focus on ... appointment of Paul Truex to its Board of Directors. , ... CEO of Anthera Pharmaceuticals - a private pharmaceutical company focused ...
Cached Biology Technology:UGA, UPR grant license for long-persistence glow materials, in any color 2UGA, UPR grant license for long-persistence glow materials, in any color 3UGA, UPR grant license for long-persistence glow materials, in any color 4Swedish-American Life Science Summit (SALSS) to Address Major Issues Including Healthcare Reform, Synthetic Biology and Innovative Financing for Biotechs 2Swedish-American Life Science Summit (SALSS) to Address Major Issues Including Healthcare Reform, Synthetic Biology and Innovative Financing for Biotechs 3Swedish-American Life Science Summit (SALSS) to Address Major Issues Including Healthcare Reform, Synthetic Biology and Innovative Financing for Biotechs 4Eiger BioPharmaceuticals Appoints Paul Truex to Board of Directors 2
... RNAi Kit is optimized for ... amounts of ready-to-use dsRNA for ... The MEGAscript RNAi Kit is ... transcription technol-ogy and includes reagents ...
... actuators as building blocks, Parker can ... ,robotic solutions that are ideal for ... base ,system, Parker can also integrate ... structures, and ,guarding., Standard or ...
... is the smallest electronic pressure controller ... mm. Parker configured this unit specifically for ... markets. Used in carrier gas flow control, ... dispensing, and hydro-dynamic focusing, the OEM-EPC offers ...
...
Biology Products: