Navigation Links
Transgenics transformed
Date:10/18/2007

e. Then they screen the gene-altered plants to find the few that might be suitable for commercial use. If they want to add two genes, they create twice as many new plants, screen for single-gene successes, then cross breed them to get both new genes, a slow and laborious process.

Instead, Preuss and colleagues have constructed MMCs that contain DNA sequences found in maize centromeres, the chromosomal regions needed for inheritance. Rather than inserting the new genes randomly into a plant's natural chromosomes, these mini-chromosomes remain separate.

As a result, the new genes can be arranged in a defined sequence, with each gene surrounded by the desired regulatory mechanisms. This results in more consistent and controlled expression. The whole cassette of genes is passed on as a group during cell division as well as to the next generation.

In their PLoS paper, the researchers characterized the behavior of the maize mini-chromosome through four generations. Using a gene for red color as a marker, they showed that the added genes are expressed "in nearly every leaf cell, indicating stability through mitosis" -- the process in which a cell duplicates its chromosomes to generate two identical daughter cells.

They also show that the MMC is efficiently passed on through meiosis, the creation of gametes, to the next generation, at ratios "approaching Mendelian inheritance."

Taken together, the authors conclude, the maize mini-chromosome, once introduced, behaves much like an ordinary chromosome. It remains distinct from the other chromosomes. Its gene cassette is structurally stable from generation to generation. The genes it carries are expressed and it is transmitted through mitosis and meiosis.

This development has not gone unnoticed. Six years ago, Preuss and two of her post-doctoral students at the University, Gregory Copenhaver and Kevin Keith, started Chromatin to refine and apply this technology. On Octobe
'/>"/>

Contact: John Easton
john.easton@uchospitals.edu
773-702-6241
University of Chicago Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra
2. Stem cells from brain transformed to produce insulin at Stanford
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2015)...  VOXX International Corporation (Nasdaq: VOXX ) ... Definitive Agreement to purchase the assets, inclusive of ... EyeLock through an acquiring entity.  Upon consummation of ... in the acquiring entity. The closing of the ...  Expanding on its existing supply chain and distribution ...
(Date:8/12/2015)... 12, 2015 As the digital ... innovation and advanced biometrics technology is accelerating beyond expectations.  ... rely on using their credit cards, the digital currency, ... for payment services led by companies in the space ... Google, Inc. (NASDAQ: GOOG ), Apple Inc. (NASDAQ: ...
(Date:8/10/2015)... The latest 364 page report from business intelligence provider ... border security market . Visiongain assesses that this ... Now: Border security is hard to achieve and harder to ... you need to know about - and more importantly, you ... this will impact your company and the border security industry ...
Breaking Biology News(10 mins):VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 2VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 3VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 4VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 2Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 4Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 6Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 2Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 3Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 4Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 5Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 6Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 7Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 8Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 9
... REDWOOD CITY, Calif., Dec. 2 DigitalPersona, Inc., a ... an agreement with IBM to deploy a new model ... 500 retail systems. The DigitalPersona U.are.U® 4500HD offering allows ... so that specific transactions can be linked to the ...
... of carbon about a nanometer in diameterhave been highly ... wires in molecular devices, or hydrogen storage components for ... at the National Institute of Standards and Technology (NIST) ... to the list: detection and destruction of an aggressive ...
... at the University of Southampton,s School of Ocean and ... (NOCS) has formally described four new species of king ... the new species in the Smithsonian Collections of the ... significance of the find, she said: "King crabs include ...
Cached Biology News:DigitalPersona Fingerprint Sensor Technology Ships on IBM SurePOS 500 Retail Systems 2Combining nanotubes and antibodies for breast cancer 'search and destroy' missions 2King crab family bigger than ever 2
(Date:8/31/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/v7fdpx/argentina ) ... Sensors Market - Growth, Trends & Forecasts (2014-2020)" ... Biomedical Sensors market is estimated at $0.17 billion by ... 2014-2020 The near future will bring Biomedical ... each individual. These sensors can be set to trigger ...
(Date:8/31/2015)... Research and Markets ( http://www.researchandmarkets.com/research/53wxp3/israel_biomedical ) has announced the ... Growth, Trends & Forecasts (2014-2020)" report to their ... is estimated at $0.19 billion by 2018 at a ... The near future will bring biomedical sensors that are ... sensors can be set to trigger alerts when unpredictable ...
(Date:8/31/2015)... -- For people with Down syndrome, news from Elixirgen, ... located in the Science + Technology Park at Johns ... yet for people with Down syndrome and other chromosome disorders ... and Edwards syndrome aneuploidies in human cell cultures, " ... plans to develop this technology into a treatment for ...
(Date:8/31/2015)... , Aug. 31, 2015  RXi Pharmaceuticals ... focused on discovering and developing innovative therapies primarily ... announced that the 30-day review period following the ... for ocular indications with the U.S. Food and ... is now active. Logo -  ...
Breaking Biology Technology:Argentina Biomedical Sensors Market Report 2015 - Growth, Trends & Forecasts 2014-2020 2Israel Biomedical Sensors Market 2015 - Growth, Trends & Forecasts to 2020 2New Down syndrome therapy discovered 2RXi Pharmaceuticals Announces Advancements in its Ophthalmology Clinical Program with RXI-109 2RXi Pharmaceuticals Announces Advancements in its Ophthalmology Clinical Program with RXI-109 3RXi Pharmaceuticals Announces Advancements in its Ophthalmology Clinical Program with RXI-109 4
... ABBOTT PARK, Ill. and SAN DIEGO , ... ) and Neurocrine Biosciences, Inc. (Nasdaq: NBIX ) ... agreement to develop and commercialize elagolix for the treatment ... gonadotropin-releasing hormone (GnRH) antagonist, which has recently completed a ...
... , ... The mother of a previously healthy 20 year old woman found dead four ... United States Supreme Court case where the Court has been asked to bar ... the Court were to bar such lawsuits, manufacturers would have a lessened incentive ...
... 11, 2010 Researchers at Texas A&M University College of ... with the successful delivery of a foal using oocytes from ... The delivery of the foal highlights Texas A&M,s long tradition ... great experience for the owner of the new foal., "I,ve ...
Cached Biology Technology:Abbott and Neurocrine Announce Global Agreement to Develop and Commercialize Elagolix for the Treatment of Endometriosis 2Abbott and Neurocrine Announce Global Agreement to Develop and Commercialize Elagolix for the Treatment of Endometriosis 3Abbott and Neurocrine Announce Global Agreement to Develop and Commercialize Elagolix for the Treatment of Endometriosis 4Abbott and Neurocrine Announce Global Agreement to Develop and Commercialize Elagolix for the Treatment of Endometriosis 5Supreme Court Amicus Brief Filed Opposing Lawsuit Protection for Manufacturers of Defectively Designed Vaccines 2Texas A&M veterinary researchers achieve cloning first 2Texas A&M veterinary researchers achieve cloning first 3
...
... the first biological reagent that ... and not just by inhibiting ... anti-mycoplasma agent that can be ... directly. The cytotoxicity of Mynox ...
... can be used to label ... covalently bound acridinium NHS ester ... presence of hydrogen peroxide. Acridinium ... used as a detection method ...
... mobility shift assay (EMSA) is a powerful ... to as gel shift or gel retardation, ... that when subjected to electrophoresis, free DNA ... The Pierce LightShift Chemiluminescent EMSA Kit is ...
Biology Products: