Navigation Links
Transgenic songbirds provide new tool to understand the brain
Date:9/29/2009

You can learn a lot from an animal. By manipulating the DNA of mice, flies, frogs and worms, scientists have discovered a great deal about the genes and molecules behind many of life's essential processes. These basic functions often work about the same in people as they do in "model" animals. But if you want to study more sophisticated cognitive processes such as humans' ability to learn language from one another, you need a more sophisticated organism. For the first time, researchers have devised a way to alter the genes of the zebra finch, one of a handful of social animals that learn to "speak" by imitating their fellows.

After decades of studying the behavior and anatomy of vocal learning, scientists will be able to use the technique to explore vocal learning at the molecular level. The new tool, reported online in the September 28 issue of PNAS Early Edition, may also reveal secrets about exactly how, when and why some neurons are replaced in the adult brain.

"The roadblock had been that you couldn't manipulate the genes," says Fernando Nottebohm, Dorothea L. Leonhardt Professor and head of the Laboratory of Animal Behavior at The Rockefeller University, where the research was conducted. "Ultimately, you have to understand how things are working at the most basic molecular level, and this will take our research there."

Nottebohm, Research Associate Robert Agate and colleagues adapted a method used to alter quail genes for use in the finch. The researchers used an HIV-based lentivirus that is able to insert attached genes into the genome of the hosts it infects. To prove the method works, the scientists inserted genes that produce green fluorescent protein in cells throughout the body. They found that they had to inject at least 10 times as much of the viral vector into finch embryos than in quail for the genes to take root. But after refining the method, they produced several birds that had incorporated the genes into th
'/>"/>

Contact: Brett Norman
bnorman@rockefeller.edu
212-327-7613
Rockefeller University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Transgenic maize is more susceptible to aphids
2. Transgenics transformed
3. Is transgenic cotton more profitable?
4. First draft of transgenic papaya genome yields many fruits
5. Risks involved with transgenic fish
6. Migrating songbirds learn survival tips on the fly
7. Songbirds may hold key to advances in treatment of brain degeneration
8. Beavers: Dam good for songbirds
9. M2SYS Partners With Gnosis Medical Services to Provide Accurate Patient Identification in Developing Countries Through Innovative Biometrics Solution
10. Improved e-jet printing provides higher resolution and more versatility
11. Canada provides $1.4M for removal of hazardous trees from provincial recreation sites
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... the leading source of biometrics industry news, interviews and thought ... "When we launched FindBiometrics 12 years ago the industry ... and CEO of FindBiometrics. "Now it,s maturing very quickly. More ... on a very broad scale.  We are known for providing ...
(Date:1/22/2015)... NXT-ID, Inc. (NASDAQ: NXTD and NXTDW) a biometric ... recent success of the Wocket™ smart wallet at CES 2015 in ... named as one of the "11 Hot Products at CES" in a ... CES So Far" by Newseveryday.com and "The top 10 gadgets from CES ...
(Date:1/22/2015)... 2015   EyeLock, Inc. , a market leader of iris-based ... Gerber to the new role of Senior Vice President ... development of mobile platforms and wearable solutions for EyeLock,s technologies. ... in the semiconductor industry to his role at EyeLock, with ...
Breaking Biology News(10 mins):Identity Industry Leading Publication Debuts New Look As Biometrics Hit Mainstream 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3EyeLock Names Steve Gerber as Senior Vice President of Mobile and Wearables 2
... today called on Congress to take legislative action that ... research to proceed, in light of U.S. District Judge ... on federally funded research using embryonic stem cells. ... Act (H.R. 4808) introduced in March 2010 by Representatives ...
... interest grows in feeding distillers dried grains with solubles (DDGS) ... digestibility of this alternative feed option. "Previous research shows ... than that of corn, pigs have lower digestibility of energy ... of I associate professor in the Department of Animal Sciences. ...
... PHILADELPHIA - University of Pennsylvania biologists studying ... major contributing factor to the maternal age-associated increase ... of chromosomes during reproductive cell division. Using ... basic fact of reproductive life is most likely ...
Cached Biology News:Research!America asks Congress to support embryonic stem cell research now 2Swine researchers seek answers to fiber's low digestibility 2Why the biological clock? Penn study says aging reduces centromere cohesion, disrupts reproduction 2
(Date:1/22/2015)... Calif. , Jan. 22. 2015  Varian Medical Systems (NYSE: ... software, has been honored for its commitment to sustainability with ... companies. Varian is the highest ranked healthcare equipment company among ... today during the World Economic Forum at Davos, ...
(Date:1/22/2015)... 2015  Derma Sciences, Inc. (Nasdaq: DSCI ... wound care, announces that AMNIOEXCEL® and AMNIOMATRIX®, amniotic ... to the Premier, Inc. Regenerative Skin Grafting contract ... AMNIOEXCEL® and AMNIOMATRIX® product lines, which continue to ...
(Date:12/24/2014)...  United Therapeutics Corporation (NASDAQ: UTHR ) announced ... has submitted a pre-market approval application to the U.S. ... Medtronic,s SynchroMed ® II implantable drug infusion system ... Therapeutics, Remodulin ® (treprostinil) Injection delivered intravenously to ...
(Date:12/24/2014)... Dec. 24, 2014  Vermillion, Inc. (Nasdaq:   VRML), ... announced today that the Company closed its previously ... Management, Jack W. Schuler , Birchview Fund ... $10.5 million, before offering expenses.  The proceeds will ...
Breaking Biology Technology:Varian Honored Among World's 100 Most Sustainable Corporations 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 3United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 4Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3
... ... directory service and website at www.TrustedLASIKSurgeons.com in order to provide ... highly qualified eye surgeon who can help them attain better vision. ... process ensuring that only those who are among the best in LASIK, ...
... ... crops offered to the biofuel industry? According to Jatro-Entrepreneur Ruud Van Eck, ... controversy in an exclusive interview with the 2nd JatrophaWorld Africa team. A ... his Jatropha cultivation project for jatropha oil in Tanzania, is now available ...
... accurate global weather forecasts and a better understanding of ... by engineers at Queen,s University Belfast,s Institute of Electronics, ... team has developed a high performance electronic device - ... - that is to be used in future European ...
Cached Biology Technology:Trusted LASIK Surgeons Welcomes Fort Lauderdale Vision Correction Surgery Expert Raymond P. Gailitis, M.D., F.A.C.S. 2Trusted LASIK Surgeons Welcomes Fort Lauderdale Vision Correction Surgery Expert Raymond P. Gailitis, M.D., F.A.C.S. 3Trusted LASIK Surgeons Welcomes Fort Lauderdale Vision Correction Surgery Expert Raymond P. Gailitis, M.D., F.A.C.S. 4Trusted LASIK Surgeons Welcomes Fort Lauderdale Vision Correction Surgery Expert Raymond P. Gailitis, M.D., F.A.C.S. 5Trusted LASIK Surgeons Welcomes Fort Lauderdale Vision Correction Surgery Expert Raymond P. Gailitis, M.D., F.A.C.S. 6Trusted LASIK Surgeons Welcomes Fort Lauderdale Vision Correction Surgery Expert Raymond P. Gailitis, M.D., F.A.C.S. 7Trusted LASIK Surgeons Welcomes Fort Lauderdale Vision Correction Surgery Expert Raymond P. Gailitis, M.D., F.A.C.S. 8Controversies on Jatropha Water-Footprint, Jatropha Cultivation for Biofuel in Tanzania and More on Jatropha Oil Shared by Jatro-Entrepreneur Ruud Van Eck. 2Controversies on Jatropha Water-Footprint, Jatropha Cultivation for Biofuel in Tanzania and More on Jatropha Oil Shared by Jatro-Entrepreneur Ruud Van Eck. 3Research breakthrough will lead to more accurate weather forecasts 2
FITC~Bovine Serum Albumin...
... provides the premium quality siRNAs you need ... can be readily ordered online by providing ... by providing the sense and antisense siRNA ... and Silencer Pre-designed siRNAs, which are already ...
, Premium quality synthesis and purification , You provide the sequence, we'll do the rest , Rigorous quality control , Your choice of purification method, amount and format , Available annealed...
Ready for formulation or direct injection into animals Provided in convenient 100, 250, 1000 and 10,000 nmol sizes HPLC purified, salt free, sterile filtered, and endotoxin tested ...
Biology Products: