Navigation Links
Training cells to perform Boolean functions? It's logical
Date:5/31/2012

Johns Hopkins scientists have engineered cells that behave like AND and OR Boolean logic gates, producing an output based on one or more unique inputs. This feat, published in the May issue of Nature Chemical Biology, could eventually help researchers create computers that use cells as tiny circuits.

Study leader Takanari Inoue, Ph.D., an assistant professor in the Department of Cell Biology and member of the Institute of Basic Biomedical Sciences' Center for Cell Dynamics at the Johns Hopkins University School of Medicine, explains that many researchers are striving to mimic devices in everyday use by engineering new qualities into biological materials, including biomolecules and cells. Several of those engaged in this relatively new field, known as synthetic biology, have tried to create biological computers.

At the heart of both the biological and the more everyday silicon-based variety of computers are Boolean logic gates, which produce responses that vary depending on what type and how many inputs they receive. For example, AND gates need two unique inputs to generate an output. In contrast, OR gates generate an output based on whether they receive one input, or another, or both.

Inoue says that previous research has shown some success in generating logic gates based on biomolecules in test tubes or petri dishes. However, he adds, developing logic gates using whole cells has proven significantly trickier. Most previous efforts have taken advantage of cells' transcriptional machinery the cellular processes that read genes to create proteins to generate an output signal. But transcription can be a slow process, taking from minutes to days to produce the desired response.

"People like to have speedy computation," Inoue says. "We were hoping to achieve computation in cells on the order of seconds, which is significantly faster than what people have achieved thus far."

To accomplish their goal, the resear
'/>"/>

Contact: Audrey Huang
audrey@jhmi.edu
410-614-5105
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Researchers develop new self-training gene prediction program for fungi
2. NC State takes lead in crime scene investigation training
3. National and international doctoral training
4. Virtual reality: Keyhole surgeons training could help meet European working time directives
5. Biophysical sciences program receives $2 million training grant
6. Building strong bones: Running may provide more benefits than resistance training, MU study finds
7. Stimulus-funded university research addressing issues from climate change to cancer, creating jobs and training a new generation of scientists
8. Concordia University to build innovative centre for health research and training
9. Kent State receives $2.7 million NSF training grant for environmental aquatic resource sensing
10. Rockefeller Foundation supports expansion, training of e-health work force in developing world
11. Less is more when restraining calories boosts immunity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2015)... -- NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the ... commerce market, reminds investors and media that  Mr. David ... CARTES SECURE CONNEXIONS AMERICA 2015, held in Washington ... three-day conference is organized into a series of nine session ... Global Fraud: Where is the Trust in Cyberspace? and ...
(Date:4/27/2015)... LAUDERDALE, Fla. , Apr. 27, 2015 ... of access control and security systems is pleased to ... the company as a consultant and member of its ... is widely known as a thought leader in ... Distance Learning Technology Group, and has published studies and ...
(Date:4/20/2015)... 20, 2015 The announcement comes ... Glenbeigh Records Management (GRM), Ireland,s foremost ... Bank. Having built up an impressive track record of clients ... player within the records management sector in Dubai ... is GCC staffbase and employ a further eight staff members ...
Breaking Biology News(10 mins):NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 2Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 4Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 2Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 3
... released today in the EarlyView of Ecology Letters ... shift in biomes caused by a warming climate. The ... Center and three other institutions based in Alaska and ... tree-ring data set. Patterns observed support current hypotheses regarding ...
... It,s a discordant note in the symphony of ... Stem cells hold enormous promise in regenerative medicine, thanks ... They have made it possible to markedly improve the ... cases of dystrophy, skin grafts for treating burn victims, ...
... breakthrough, a new blood pressure measurement device is set to ... new approach, invented by scientists at the University of Leicester ... treat their patients more effectively because it gives a more ... by measuring the pressure close to the heart the ...
Cached Biology News:New study illustrates shifting biomes in Alaska 2Reprogrammed stem cells hit a roadblock 2Groundbreaking technology will revolutionize blood pressure measurement 2Groundbreaking technology will revolutionize blood pressure measurement 3Groundbreaking technology will revolutionize blood pressure measurement 4
(Date:5/29/2015)... 2015 BerGenBio AS ("BerGenBio" or ... an abstract on the latest data on BGB324, the ... receptor tyrosine kinase, and BGB10C9, an Axl function-blocking monoclonal ... in conjunction with the 2015 American Society of Clinical ... , May 29 - June 2, 2015. ...
(Date:5/29/2015)... 29, 2015 Market Publishers Ltd ... signed a partnership agreement for quality market research ... distribute and sell research reports worked out by ... Department, commented upon the agreement: “Chem-Report is a ... petroleum and chemical markets on global and country ...
(Date:5/29/2015)... Texas , May 29, 2015  Caris ... focused on fulfilling the promise of precision medicine, ... studies that demonstrate the clinical utility of Caris ... tumor profiling service, in helping to identify targeted ... tumors. In each of the studies, results of ...
(Date:5/29/2015)... Seoul Semiconductor (CEO: Chung-hoon Lee, http://www.seoulsemicon.com ... 28th announced that it will increase the global ... efficient and high reliable LED product line-up for ... has developed efficient and reliable LED packages for ... for headlamps to global auto makers. Seoul Semiconductor’s ...
Breaking Biology Technology:BGB324 and BGB10C9 Show Promise in Models of Pancreatic Cancer 2BGB324 and BGB10C9 Show Promise in Models of Pancreatic Cancer 3Market Publishers Ltd and Chem-Report Sign Partnership Agreement 2Market Publishers Ltd and Chem-Report Sign Partnership Agreement 3Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 2Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 3Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 4Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 5Multi-Platform Tumor Profiling from Caris Life Sciences Identifies Targeted Treatment Options for Patients with Rare and/or Aggressive Tumors 6Seoul Semiconductor Increases the Global Automotive LED Market Share with its High Efficient and Reliable LEDs for Automotive Lightings 2
...  Dyadic International, Inc. (OTC Pink: DYAI), a global biotechnology ... results for the first quarter ended March 31, 2012 ... will host a conference call at 5:00 p.m. Eastern ... http://photos.prnewswire.com/prnh/20110621/CL06708LOGO ) Those wishing to ...
... announced today the launch and immediate availability of the GS GType ... variation detection in four key human genes using the company,s ... sequence-based assays offer a new solution for cancer researchers investigating the ... RUNX1 genes, which are known to be associated with ...
... research team this week will present findings that they ... and breast cancer. "Cells have different ... chemical name for alcohol, that represent a potential risk ... pharmacology and toxicology at the Universidad Autonoma del Estado ...
Cached Biology Technology:Roche Launches 454 Sequencing Assays for High Sensitivity Genetic Variant Detection in Leukemia Samples to Drive Blood Cancer Research Worldwide 2Roche Launches 454 Sequencing Assays for High Sensitivity Genetic Variant Detection in Leukemia Samples to Drive Blood Cancer Research Worldwide 3Researchers Find Potential Link Between Drinking Alcohol And Breast Cancer 2Researchers Find Potential Link Between Drinking Alcohol And Breast Cancer 3
The BD PhosFlow Fix Buffer I can be used for the simultaneous fixation and permeabilization of cells prior to intracellular staining. Applications: Intracellular Staining (Flow) Storage Temperature:...
... GenBank Accession Number : ... (C-QSQENQDTRPKVKAKK), corresponding to amino acids ... Formulation: antiserum in 0.05% sodium ... Assurance: routinely evaluated by immunoblot ...
Request Info...
...
Biology Products: