Navigation Links
Toxin detection as close as an inkjet printer
Date:7/13/2009

If that office inkjet printer has become just another fixture, it's time to take a fresh look at it. Similar technology may soon be used to develop paper-based biosensors that can detect certain harmful toxins that can cause food poisoning or be used as bioterrorism agents.

In a paper published in the July issue of Analytical Chemistry, John Brennan and his research team at McMaster University, working with the Sentinel Bioactive Paper Network, describe a method for printing a toxin-detecting biosensor on paper using a FujiFilm Dimatix Materials Printer.

The researchers demonstrated the concept on the detection of acetylcholinesterase (AChE) inhibitors such as paraoxon and aflatoxin B1 on paper using a "lateral flow" sensing approach similar to that used in a home pregnancy test strip.

The process involves formulating an ink like the one found in computer printer cartridges but with special additives to make the ink biocompatible. An ink comprised of biocompatible silica nanoparticles is first deposited on paper, followed by a second ink containing the enzyme, and the resulting bio-ink forms a thin film of enzyme that is entrapped in the silica on paper. When the enzyme is exposed to a toxin, reporter molecules in the ink change colour in a manner that is dependent on the concentration of the toxin in the sample.

This simple and cost-effective method of adhering biochemical reagents to paper is expected to bring the concept of bioactive paper a significant step closer to commercialization. The goal for bioactive paper is to provide a rapid, portable, disposable and inexpensive way of detecting harmful substances, including toxins, pathogens and viruses, without the need for sophisticated instrumentation. The research showed that the printed enzyme retains full activity for at least two months when stored properly, suggesting that such sensor strips should have a good shelf life.

Portable bio-sensing papers are expected to be extremely useful in monitoring environmental and food-based toxins, as well as in remote settings in less industrialized countries where simple bioassays are essential for the first stages of detecting disease.

Applications for bioactive paper also include clinical applications in neuroscience, drug assessment, and pharmaceutical development.


'/>"/>

Contact: Gene Nakonechny
genen@mcmaster.ca
905-525-9140 x26781
McMaster University
Source:Eurekalert  

Related biology news :

1. UNH: Pavement sealcoat a source of toxins in stormwater runoff
2. Link between unexploded munitions in oceans and cancer-causing toxins determined
3. Mycotoxin Research joins Springers life sciences journals program
4. Case Western Reserve researchers looking at light-induced toxins in air and water
5. NYU scientists discover dangerous new method for bacterial toxin transfer
6. Aerosol toxins from red tides may cause long-term health threat
7. Test of bacteria toxin delivery system could pave way for new antibiotic drugs
8. Scientists determine drug target for the most potent botulinum neurotoxin
9. Defining genes role may lead to prevention of dangerous corn toxin
10. Technology uses live cells to detect food-borne pathogens, toxins
11. Using carbon nanotubes to seek and destroy anthrax toxin and other harmful proteins
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Toxin detection as close as an inkjet printer
(Date:2/2/2017)... , Feb. 2, 2017  EyeLock LLC, a market ... new white paper " What You Should Know About ... of ensuring user authenticity is a growing concern. In ... of users. However, traditional authentication schemes such as username/password ... Biometric authentication offers an elegant solution to the ...
(Date:2/1/2017)... Massachusetts , February 1, 2017 IDTechEx ... events on emerging technology, announces the availability of a new report, ... Continue Reading ... ... in industrial and collaborative robots. Source: IDTechEx Report "Sensors for Robotics: ...
(Date:1/30/2017)... Jan. 30, 2017   Invitae Corporation (NYSE: ... genetic information companies, today announced that it will report ... provide 2017 guidance on Monday, February 13, 2017, and ... day at 4:45 p.m. Eastern / 1:45 p.m. Pacific. ... will briefly review financial results, guidance, and recent developments ...
Breaking Biology News(10 mins):
(Date:2/21/2017)... CA (PRWEB) , ... February 21, 2017 , ... ... the VTX-1 Liquid Biopsy System , a fully automated benchtop system for ... technology. The VTX-1 is being launched at the Molecular Medicine Tri Conference (Tri-Con) ...
(Date:2/21/2017)... CA (PRWEB) , ... February 21, 2017 , ... The ... prospects for their use, in multiple areas of medicine, due to their differentiating characteristics. ... division, and they have the ability to be induced to become tissue or organic-specific ...
(Date:2/21/2017)... (PRWEB) , ... February 21, 2017 , ... ... creating transformative design and manufacturing solutions for original equipment manufacturers (OEMs) , today ... 2017 marks Creation Technologies’ third consecutive year winning in its category of electronics ...
(Date:2/21/2017)... YORK , Feb. 21, 2017   Logicalis ... an international IT solutions and managed services provider ( ... – Service Desk for Epic. The new service will ... internal Epic resources by giving physicians, nurses and other ... specialists for tier-one support. This will allow hospital IT ...
Breaking Biology Technology: