Navigation Links
Toward making 'extended blood group typing' more widely available
Date:7/14/2010

Scientists are reporting an advance toward enabling more blood banks to adopt so-called "extended blood group typing," which increases transfusion safety by better matching donors and recipients. Their report on a new, automated genetic method for determining a broader range of blood types appears in ACS' Analytical Chemistry, a semi-monthly journal.

Christophe Marquette and colleagues explain that most blood banks still use a century-old blood approach to blood typing. It identifies blood group antigens on red blood cells -- proteins that must match in donor and recipient to avoid potentially serious transfusion reactions. Most blood currently is typed for only a few of the 29 known human blood groups, even though some rare blood groups can affect the outcome of a transfusion. Commercial technology does exist for extended typing with DNA tests. However, it is expensive, difficult to use, and suited more for research labs than high-volume blood centers, they state. Wide adoption of extended blood group typing, they note, requires a test that can handle the high volume of blood processed each year -- 14 million donations in the United States, for instance, and 20 million in Europe.

The study describes evaluation of the new more affordable method, called the HiFi Blood 96, which types blood with DNA testing in a high-speed automated procedure. Tests on 293 human blood samples demonstrated the performance and reliability of the new method. The report compares HiFi Blood 96 to existing commercial tests, and discusses improvements that are underway.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert  

Page: 1

Related biology news :

1. Scientists locate oil plume extending toward Dry Tortugas
2. International panel recommends redirecting the world community toward sustainable growth
3. Scientists make important step toward stopping plaque-like formations in Huntingtons disease
4. New steps toward a universal flu vaccine
5. Toward simplifying treatment of a serious eye infection
6. Toward a urine test for detecting colon cancer
7. Congress takes another stride toward public access to research
8. Metabolic fingerprints offer fresh clues and a new path toward personalized medicine
9. Toward safer plastics that lock in potentially harmful plasticizers
10. An electrifying advance toward tomorrows power suits
11. Discovery points toward anti-inflammation treatment for blinding disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Toward making 'extended blood group typing' more widely available
(Date:3/23/2017)... 2017 Research and Markets has announced the ... Trends - Industry Forecast to 2025" report to their offering. ... The Global ... of around 8.8% over the next decade to reach approximately $14.21 ... market estimates and forecasts for all the given segments on global ...
(Date:3/22/2017)... 2017 Vigilant Solutions , a vehicle ... agencies, announced today the appointment of retired FBI special ... safety business development. Mr. Sheridan brings more ... a focus on the aviation transportation sector, to his ... Mr. Sheridan served as the Aviation Liaison Agent Coordinator ...
(Date:3/16/2017)... , March 16, 2017 CeBIT 2017 - Against identity fraud ... Continue Reading ... Used combined in one project, multi-biometric solutions provide a ... Used combined ... ...
Breaking Biology News(10 mins):
(Date:4/27/2017)... ... 2017 , ... Proscia Inc., a data ... has the potential to eliminate subjectivity in the detection and classification of breast ... of the 2017 ISBI CAMELYON Digital Pathology Challenge, organized by the ...
(Date:4/27/2017)... ... April 27, 2017 , ... This month Quorum Review ... that simplifies research studies, accelerates study startup, and improves participant engagement. Developed by ... the first and only IRB-integrated eConsent solution . , “Our mission at ...
(Date:4/27/2017)... ... April 27, 2017 , ... During the course of this ... for 1,25-Dihydroxyvitamin D can enhance clinical practice. Participants will learn the medical indications ... , Dr. Gregory Plotnikoff, senior consultant with Minnesota Personalized Medicine, will be the ...
(Date:4/27/2017)... , ... April 27, 2017 ... ... announced a comprehensive rebrand and a name change to Fluence Analytics. ... and laboratory monitoring of polymer and biopharmaceutical manufacturing processes and R&D applications. ...
Breaking Biology Technology: