Navigation Links
Toward an alternative for antibiotics to fight bacterial infections?
Date:7/3/2012

VIB researcher Mohamed Lamkanfi, connected to the Ghent University, discovered that mice that do not produce the receptor protein NLRP6, are better protected against bacterial infections and can easier remove bacteria from the body. Therapeutic drugs that neutralize NLRP6 could be a possible treatment option, in addition to the use of antibiotics, for fighting bacterial infections. His research was published in the leading scientific magazine Nature.

Mohamed Lamkanfi (VIB Ghent University): "Our lab investigates the role of the innate immunity, which is of crucial importance to protect the body against bacteria and other pathogens. We started looking for genetic mutations that lead to an increased sensitivity to infections. Our research showed that mice with NLRP6 are less resistant to bacteria and have greater difficulty removing the bacteria from the body. This NLRP6 plays a disastrous role in the entire process."

New therapeutic track?

The discovery of Mohamed Lamkanfi is not insignificant. The first line treatment for bacterial infections is and will remain antibiotics, of course. However, due to the intensive use of antibiotics in the fight against infections, also the resistance of the bacteria grows against this group of medicines. Sometimes this makes it much more difficult for doctors to treat a patient efficiently.

Mohamed Lamkanfi: "Our search for products to help immune systems in the fight against bacterial infections is very important. In spite of the availability of antibiotics bacterial infections continue to pose a serious threat to public health all over the world. Now that we have exposed the role of the receptor protein NLRP6 in the immune response, we can start thinking about the clinical application thereof for the treatment of bacterial infections. A vaccine, in my opinion, seems less suitable, but a medicine that neutralizes the receptor protein NLRP6, is a possibility. Of course not in the immediate future, but it does deserve all the attention to research this further."


'/>"/>

Contact: Sooike Stoops
sooike.stoops@vib.be
32-474-289-252
VIB (the Flanders Institute for Biotechnology)
Source:Eurekalert

Related biology news :

1. A step toward minute factories that produce medicine inside the body
2. Towards an agroforestry policy in Indonesia
3. Amniotic fluid yields alternatives to embryonic stem cells
4. Scripps Research Institute Scientists Develop Alternative to Gene Therapy
5. Pasta made from green banana flour a tasty alternative for gluten-free diets
6. NIST launches new website to educate industry about alternatives to mercury thermometers
7. Hot sauce ingredient reduces beer belly fat as a weight-loss surgery alternative
8. Bacteria discovery could lead to antibiotics alternatives
9. Yeast cell reaction to Zoloft suggests alternative cause, drug target for depression
10. AZM alternatives for apple growers against codling moth
11. University of Minnesota invention helps advance reliability of alternative energy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/4/2017)... --  EyeLock LLC , a leader of iris-based identity ... and Trademark Office (USPTO) has issued U.S. Patent No. ... iris image with a face image acquired in sequence ... th issued patent. "The issuance ... multi-modal biometric capabilities that have recently come to market ...
(Date:3/30/2017)... March 30, 2017 The research team of ... three-dimensional (3D) fingerprint identification by adopting ground breaking 3D fingerprint minutiae ... realm of speed and accuracy for use in identification, crime investigation, ... cost. ... A research ...
(Date:3/28/2017)... India , March 28, 2017 ... IP, Biometrics), Hardware (Camera, Monitors, Servers, Storage Devices), Software ... Vertical, and Region - Global Forecast to 2022", published ... Billion in 2016 and is projected to reach USD ... between 2017 and 2022. The base year considered for ...
Breaking Biology News(10 mins):
(Date:4/26/2017)... Myrtle Beach, SC (PRWEB) , ... April 26, ... ... for the mind, has teamed up with NASA to showcase the future of ... NASA’s Space Launch System (SLS) rocket and Orion spacecraft and includes a guest ...
(Date:4/26/2017)... RESTON, Va. (PRWEB) , ... April 26, 2017 ... ... to make headlines and drive high-level conversations among healthcare industry stakeholders, the discussion ... Healthcare Environment – taking place May 15-18, 2017 in Los Angeles, Calif. Hosted ...
(Date:4/25/2017)... PROVIDENCE, R.I. , April 25, 2017 /PRNewswire/ ... EpiVax, Inc. ("EpiVax") has licensed its novel immune-modulating technology ... in autoimmune disease and allergy. Tregitopes, ... discovered in human immunoglobulin by EpiVax CEO ... Martin. Similar to intravenous immunoglobulin G, an autoimmune ...
(Date:4/24/2017)... Labs announced today the offer of whole genome sequencing (WGS) ... individuals have been able to access WGS at $1,000, this ... EUR 1,000. The sequencing includes bioinformatics analysis and ... informed decisions about disease monitoring, prevention, nutrition, exercise, health monitoring ... ...
Breaking Biology Technology: