Navigation Links
Toward an alternative for antibiotics to fight bacterial infections?
Date:7/3/2012

VIB researcher Mohamed Lamkanfi, connected to the Ghent University, discovered that mice that do not produce the receptor protein NLRP6, are better protected against bacterial infections and can easier remove bacteria from the body. Therapeutic drugs that neutralize NLRP6 could be a possible treatment option, in addition to the use of antibiotics, for fighting bacterial infections. His research was published in the leading scientific magazine Nature.

Mohamed Lamkanfi (VIB Ghent University): "Our lab investigates the role of the innate immunity, which is of crucial importance to protect the body against bacteria and other pathogens. We started looking for genetic mutations that lead to an increased sensitivity to infections. Our research showed that mice with NLRP6 are less resistant to bacteria and have greater difficulty removing the bacteria from the body. This NLRP6 plays a disastrous role in the entire process."

New therapeutic track?

The discovery of Mohamed Lamkanfi is not insignificant. The first line treatment for bacterial infections is and will remain antibiotics, of course. However, due to the intensive use of antibiotics in the fight against infections, also the resistance of the bacteria grows against this group of medicines. Sometimes this makes it much more difficult for doctors to treat a patient efficiently.

Mohamed Lamkanfi: "Our search for products to help immune systems in the fight against bacterial infections is very important. In spite of the availability of antibiotics bacterial infections continue to pose a serious threat to public health all over the world. Now that we have exposed the role of the receptor protein NLRP6 in the immune response, we can start thinking about the clinical application thereof for the treatment of bacterial infections. A vaccine, in my opinion, seems less suitable, but a medicine that neutralizes the receptor protein NLRP6, is a possibility. Of course not in the immediate future, but it does deserve all the attention to research this further."


'/>"/>

Contact: Sooike Stoops
sooike.stoops@vib.be
32-474-289-252
VIB (the Flanders Institute for Biotechnology)
Source:Eurekalert

Related biology news :

1. A step toward minute factories that produce medicine inside the body
2. Towards an agroforestry policy in Indonesia
3. Amniotic fluid yields alternatives to embryonic stem cells
4. Scripps Research Institute Scientists Develop Alternative to Gene Therapy
5. Pasta made from green banana flour a tasty alternative for gluten-free diets
6. NIST launches new website to educate industry about alternatives to mercury thermometers
7. Hot sauce ingredient reduces beer belly fat as a weight-loss surgery alternative
8. Bacteria discovery could lead to antibiotics alternatives
9. Yeast cell reaction to Zoloft suggests alternative cause, drug target for depression
10. AZM alternatives for apple growers against codling moth
11. University of Minnesota invention helps advance reliability of alternative energy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/1/2016)... YORK , Feb. 1, 2016  Today, the ... Association (AHA) announced plans to develop a first of ... computing power of IBM Watson. In the first application ... AHA, IBM (NYSE: IBM ), and Welltok will ... and health assessments with cognitive analytics, delivered on Welltok,s ...
(Date:1/25/2016)...  Glencoe Software, the world-leading supplier of image data ... provide the data management solution OMERO Plus for the ... Photo - http://photos.prnewswire.com/prnh/20160125/325328LOGO ... Phenotypic analysis measures the characteristics and behavior of ... states such as health and disease, the presence or ...
(Date:1/20/2016)... 2016   MedNet Solutions , an innovative SaaS-based ... clinical research, is pleased to announce the attainment of ... the result of the company,s laser focus on (and ... , it,s comprehensive, easy-to-use and highly affordable cloud-based technology ... Key MedNet growth achievements in 2015 include: ...
Breaking Biology News(10 mins):
(Date:2/10/2016)... ... February 10, 2016 , ... Benchmark Research, a fully-integrated ... of two long-standing principal investigators (PI) to the roles of Chief Medical Officer, ... , Dr. Laurence Chu, a Benchmark Research PI in the Austin office, will ...
(Date:2/10/2016)... ... 10, 2016 , ... LATHAM, NEW YORK... Marktech Optoelectronics will feature ... in San Francisco’s Moscone Center from February 16-18, 2016, and at the healthcare-focused ... latest InGaAs PIN diode standard packages feature a TO-46 metal can with active areas ...
(Date:2/10/2016)... ... February 10, 2016 , ... PatientCrossroads announces ... the secure online PatientCrossroads platform, has exceeded both its one-year and overall recruitment ... PROMPT study, which seeks to advance understanding of the hereditary risks for certain ...
(Date:2/10/2016)... ... 2016 , ... Global Stem Cells Group, a ... Stem Cells Network (GSCN) and its affiliate Global Medical Training Network to ... and bone marrow therapies. , Through the new collaboration, Global Stem Cells ...
Breaking Biology Technology: