Navigation Links
Toward a therapy to healing stroke
Date:12/14/2011

This release is available in German.

With 100 billion nerve cells, the brain is the most complex organ in the human body. "We want to understand the development program behind," says Dr. Steffen Scholpp from the ITG. "We want to find out how individual parts of the brain develop, this means, what makes precursor cells build a specialized area such as the thalamus." Scholpp's group at ITG studies the development of the thalamus. "It is the central interface between the brain and the outer world: Everything that is perceived via eyes, ears or the tactile sense has to pass the thalamus before it is routed to the cerebral cortex for further processing."

In the long term, the scientists want to be able to heal damaged brain parts by a tissue replacement therapy. If, for example, brain tissue is damaged after an infarct, is the body is not able to regenerate this tissue. "Today, stroke is the most frequent cause of disability acquired at adult age and due to its central role, damage of the thalamus is very serious," emphasizes Steffen Scholpp. "For this reason, we have to find a strategy to activate stem cells such that the damaged tissue can be replaced." Recently, an important step was made by the scientists: By studying zebrafish, they identified Lhx2 and Lhx9, the factors controlling the development of neurons in the thalamus. "Without these factors, the thalamus would accommodate undifferentiated nerve cells only this means, the precursory cells lack the information required for specialization," explains the biologist. Analysis of brain development in zebrafish allows conclusions to be drawn with respect to the development in all vertebrates, including human. The results of the group are published in the current issue of the PLoS Biology journal.

In the same study, Scholpp and his team identified another factor that acts as "adhesive
'/>"/>

Contact: Monika Landgraf
presse@kit.edu
49-721-608-47414
Helmholtz Association of German Research Centres
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Taking the next step toward advanced artificial limbs
2. Thinking it through: Scientists call for policy to guide biofuels industry toward sustainability
3. Scientists announce major progress towards historic Census of Marine Life in 2010
4. Study a step toward disease-resistant crops, sustainability
5. Genetic Engineering & Biotechnology News reports on the trend toward predictive toxicogenomics
6. Toward a systems biology map of iron metabolism
7. Attitudes towards assisted reproduction and preimplantation genetic diagnosis
8. NIST guides genetic genealogy labs toward improved accuracy
9. Scientists make strides toward defining genetic signature of Alzheimers disease
10. Milestone achieved toward production of malaria treatment using synthetic biology and fermentation
11. Oceans journey towards the center of the Earth
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Toward a therapy to healing stroke
(Date:4/17/2014)... and pathogens that devastate honeybees in Europe, Asia and ... do not appear to be impacting native honeybee populations ... researchers., The invasive pests include including Nosema microsporidia ... honeybees appear to be resilient to these invasive pests, ... control pests in Europe, Asia and the United States ...
(Date:4/17/2014)... many serious conditions such as heart disease, epilepsy and ... therapies. Unfortunately, there is still much scientists do not ... and unexpected insight into the structure of sodium channels ... - which are responsible for ,fine-tuning, the activity of ... recent edition of the Journal of Biological Chemistry ...
(Date:4/17/2014)... researchers have detected new early-warning signs of the potential ... have far-reaching implications for the diagnosis and treatment of ... million Americans. , "We had not expected to see ... stages," said Ann Elsner, professor and associate dean in ... the study. "We set out to study the early ...
Breaking Biology News(10 mins):East African honeybees are safe from invasive pests… for now 2East African honeybees are safe from invasive pests… for now 3Structure of sodium channels different than previously believed 2New technique detects microscopic diabetes-related eye damage 2New technique detects microscopic diabetes-related eye damage 3
... international consortium of 15 institutions from 12 European ... Norway, Romania, Sweden, The Netherlands, UK) has started ... The name stands for ,Biodiversity and Ecosystem Services: ... the effectiveness of arguments used for biodiversity protection ...
... the Arctic Ocean, the frozen soils within this region keep ... the Earth,s atmosphere. This sequestered carbon is more than 250 ... United States in the year 2009. As global temperatures slowly ... upon the carbon cycle when the permafrost thaws and releases ...
... metal-organic frameworks, with their nanoscopic pores and incredibly ... gas storage. But with millions of different structures ... University research team has developed a computational method ... in the discovery process. The new algorithm automatically ...
Cached Biology News:Preparing for a thaw: How Arctic microbes respond to a warming world 2Preparing for a thaw: How Arctic microbes respond to a warming world 3More promising natural gas storage? 2
(Date:1/15/2014)... Ill. , Jan. 15, 2014  Bill Jacobs Automotive, a ... , is teaming up with the Heartland Blood Center and ... blood drive. The drive takes place Saturday, Jan. 18 at ... - 2 p.m. (Photo: http://photos.prnewswire.com/prnh/20140115/MN46637 )  ...
(Date:1/15/2014)... 2014   Niagara Thermal Products is proud to ... Technologies LLC ("B3") as the critical thermal component supplier ... the Army Corps of Engineers.  B3 has developed the ... contaminants and destroys VOCs and other chemical pollutants, allergens ...
(Date:1/15/2014)... Cynvenio, a cancer diagnostics company focused ... analysis of tumor cells in the bloodstream, today announced ... decision support application powered by CollabRx, Inc. , ... test, Therapy Finder will provide breast cancer patients and ...
(Date:1/15/2014)... RedBrick Health , a fast-growing leader in consumer health ... EmblemHealth , the New York -based ... RedBrick Compass health assessment, combined with the RedBrick Journeys ... EmblemHealth is among the first health plans in the ...
Breaking Biology Technology:Join the Bill Jacobs Auto blood drive and receive a free oil change 2Niagara Thermal Products LLC Selected as Critical Supplier for Buffalo BioBlower Air Purification Systems 2Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 2Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 3EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 3
... 18 Opsona Therapeutics, a,biotechnology company focused on ... diseases, today announced the,completion of an EUR18M ($23M) ... expand both at an operational and clinical level. ... and Seroba Kernel,Life Sciences all participated in the ...
... Forschungsgemeinschaft (DFG, German Research Foundation) has announced that ... high-risk research projects. The Joint Committee of Germany,s ... approved funding for two new Reinhart Koselleck Projects. ... Professor Reinhard Drner, an atomic physicist from Frankfurt, ...
... found that tiny nanoparticles could be twice as likely ... liquids than previously believed. This opens up a ... in living cells, polymer composites, and high-tech foams, ... ways of further artificially enhancing this new found sticking ...
Cached Biology Technology:Opsona Therapeutics Closes EUR18M Funding 2Opsona Therapeutics Closes EUR18M Funding 3Opsona Therapeutics Closes EUR18M Funding 4Encouraging high-risk research: DFG approves funding for 2 new Reinhart Koselleck projects 2Encouraging high-risk research: DFG approves funding for 2 new Reinhart Koselleck projects 3Nanoparticles double their chances of getting into sticky situations 2