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Toward a systems biology map of iron metabolism
Date:4/28/2009

ciplinary approach to the study of molecular biosystems. We have been working with our partners at the Wake Forest University School of Medicine on several biomedical projects over the past few years and our scientific approach is delivering a solid platform for further discoveries. We have built a team of researchers with expertise in biology, mathematics, biochemical modeling, and metabolism that works closely with clinical scientists who understand the first-hand impact of iron metabolism on health. This work is helping us to build a comprehensive system-wide understanding of iron metabolism and its clinical ramifications."

VBI and Virginia Tech Mathematics Professor Reinhard Laubenbacher added: "We hope to use the iron metabolic networks as a starting point to identify changes that take place in healthy and diseased tissues. The addition of kinetic information to our structural network should permit the simulation of iron metabolism in different tissues as well as under conditions of health and disease. This should provide us with a much needed tool to look at the impact of such changes on the systems level network."


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Contact: Barry Whyte
whyte@vbi.vt.edu
540-231-1767
Virginia Tech
Source:Eurekalert

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