Navigation Links
Tooth loss strongly linked to risk of esophageal, head and neck, and lung cancer
Date:5/13/2008

PHILADELPHIA Studying thousands of patients, Japanese researchers have found a strong link between tooth loss and increased risk of three cancers esophageal, head and neck, and lung. They suggest that preservation of teeth may decrease risk of developing these diseases.

In the May issue of Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research, scientists from Aichi Cancer Center in Nagoya and Nagoya University Graduate School of Medicine speculate that bacterial infection and inflammation resulting from poor oral care that leads to tooth loss could also be driving development of these cancers. Periodontal disease is known to increase risk for stroke and heart disease.

Tooth loss is a common consequence of chronic bacterial infection and may, therefore, serve as a surrogate for chronic infection and inflammation, which in turn may be important to the pathogenesis of cancer, said the studys lead author, Akio Hiraki, Ph.D., a researcher at the Aichi Cancer Center.

Researchers measured rates of 14 different cancers and rates of tooth loss in 5,240 cancer patients in Japan, and compared those rates among 10,480 matched cancer-free participants. The researchers specifically found that people with tooth loss were 136 percent more likely to develop esophageal cancer, had a 68 percent increased risk of developing head and neck cancer and a 54 percent greater chance of developing lung cancer. The researchers also found that the rate of cancer increased proportionally to the number of teeth a patient had lost.

These increased risks were seen after researchers took into account a patients history of smoking and alcohol use.

Smaller studies have linked tooth loss to different cancers, but this is the largest study to date, and the first conducted within an Asian population, the researchers say. This is also the first study to show a link to lung cancer, they add.

Th
'/>"/>

Contact: Jeremy Moore
Jeremy.moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Page: 1 2

Related biology news :

1. Tooth Bank seeks milk teeth from 100,000 children
2. NYU dental professor discovers biological clock linking tooth growth to other metabolic processes
3. Oatmeals health claims strongly reaffirmed, science shows
4. Risk of common vaginal infection linked to preterm birth appears higher for blacks
5. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
6. Protein chatter linked to cancer activation
7. Western diet linked to increased risk of colon cancer recurrence
8. Sugary drinks, not fruit juice, may be linked to insulin
9. Brains timing linked with timescales of the natural visual world
10. Low vitamin D during pregnancy linked to pre-eclampsia
11. Genetic variant linked to odor perception
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... professor and Howard Hughes Medical Institute investigator, and ... recipients in the 2014 round of grants from ... BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Initiative ... September 30, provides more than $3 million in ... , The BRAIN Initiative, launched last year, is ...
(Date:9/30/2014)... available in German . ... most expensive foods in the world. Because they grow underground, ... the distinctive smell of truffles is not only of interest ... the direction of the Goethe University Frankfurt have discovered that ... bacteria which are trapped inside truffle fruiting bodies. , White ...
(Date:9/30/2014)... trouble getting pregnanteven with IVF? Here,s some hope: A ... The FASEB Journal , explains how ... known as PAWP, which induced embryo development in human ... embryo development by the sperm cell during fertilization. , ... a major paradigm shift in our understanding of human ...
Breaking Biology News(10 mins):Salk scientists receive $3 million for BRAIN Initiative grant 2On the trail of the truffle flavor 2Synthetic sperm protein raises the chance for successful in vitro fertilization 2
... counter-balance to the warming of our planet by greenhouse gases ... to have lost ground. , The thinning of Earth’s "sunscreen" ... extra push to the rise in global surface temperatures. The ... an improved understanding of recent climate change. In a related ...
... they don't react to internal signals urging them to die. ... Louis have found an efficient way to get a messenger ... signals. And they did it using one of the most ... itself into many different types of cells," says senior author ...
... light are providing insight into the complexities of the sense ... how the human brain works. , Investigators at Duke University ... a strain of mice whose olfactory brain cells "fire" when ... cells a gene naturally present in green algae that "turns ...
Cached Biology News:Global 'sunscreen' has likely thinned, report NASA scientists 2Global 'sunscreen' has likely thinned, report NASA scientists 3HIV protein enlisted to help kill cancer cells 2HIV protein enlisted to help kill cancer cells 3Scientists to track impact of Asian dust and pollution on clouds, weather, climate change 2Scientists to track impact of Asian dust and pollution on clouds, weather, climate change 3
(Date:9/30/2014)... 30, 2014 Fast, semi-automatic ... chemistry in documents ChemAxon , ... consulting services for life science research, launches ChemCurator, ... Markush structures from documents. Markush structures ... however generating and understanding Markush structures is a ...
(Date:9/30/2014)... and ROCKVILLE, Md., Sept. 30, 2014 BioHealth ... on commercializing market-relevant biohealth innovations and increasing access to ... announced today that venture capitalist, Tania Fernandez , ... advisor. Dr. Fernandez will be a member of the ... will provide up to $50 million in seed and ...
(Date:9/30/2014)... September 30, 2014 The custom stainless ... Boston Product Show 2014. The Boston Area Chapter of ... 23rd annual, day-long event for Wed., Oct. 1 at ... to be the largest in ISPE Boston’s long history, ... of 3,000 attendees expected. , HOLLOWAY AMERICA President ...
(Date:9/30/2014)... (PRWEB) September 30, 2014 On September 11, ... James Sherley in anticipation of a session that he will ... Toxicology Summit,” scheduled for February 17-18, 2015 in London. ... Pharma IQ asked Dr. Sherley to respond to several questions ... toxicity, challenges to evaluating stem cell toxicity, and future trends ...
Breaking Biology Technology:ChemAxon Introduces ChemCurator for Chemical Information Extraction and Markush Structure Creation 2Seasoned Life Sciences Venture Capitalist Tania Fernandez Joins BHI to Help Manage New BioHealth Gap Fund 2HOLLOWAY AMERICA to Exhibit at ISPE Boston Product Show 2014 2HOLLOWAY AMERICA to Exhibit at ISPE Boston Product Show 2014 3Adult Stem Cell Technology Center, LLC Director James L. Sherley Discusses Stem Cell Toxicology 2Adult Stem Cell Technology Center, LLC Director James L. Sherley Discusses Stem Cell Toxicology 3Adult Stem Cell Technology Center, LLC Director James L. Sherley Discusses Stem Cell Toxicology 4
... Vical Incorporated,(Nasdaq: VICL ) presentation at the ... at 1 p.m. Eastern Daylight Time, will be ... page at http://www.vical.com ., About Vical, ... on its,patented DNA delivery technologies for the prevention ...
... - Oncentra(R) RT Viewer* Officially to Launch ... ASTRO 2008, Boston, USA, September,21-24, Nucletron, a ... release of Oncentra RT Viewer. This unique innovation,in ... review,radiotherapy plans that are generated with a wide ...
... significant partial onset seizure reduction, proven ... - Keppra XR(TM) is ... press release, regulated information:,UCB announced today that the U.S. Food ... for use as,an add-on to other antiepileptic treatments for people ...
Cached Biology Technology:Vical to Present at UBS Global Life Sciences Conference 2Nucletron Announces Market Release of First Commercially Available Software to Review and Share Dicom-Based Treatment Plans for Radiotherapy 2Video: Keppra XR(TM) Approved in the U.S. 2Video: Keppra XR(TM) Approved in the U.S. 3Video: Keppra XR(TM) Approved in the U.S. 4