Navigation Links
Tomato pathogen genome may offer clues about bacterial evolution at dawn of agriculture
Date:2/7/2008

Blacksburg, Va. The availability of new genome sequencing technology has prompted a Virginia Tech plant scientist to test an intriguing hypothesis about how agricultures early beginnings may have impacted the evolution of plant pathogens.

Boris Vinatzer, assistant professor of plant pathology, physiology, and weed science in the College of Agriculture and Life Sciences, has received a $1 million, five-year Faculty Early Career Development (CAREER) award from the National Science Foundation (NSF) to investigate the pathogen that causes bacterial speck disease of tomatoes and to develop a new undergraduate course in microbial genomics.

Little is known about how plant pathogens, which were adapted to natural mixed-plant communities in pre-agriculture times, evolved into todays highly aggressive pathogens of crops cultivated in monoculture, Vinatzer said. To fill this void, this project aims at identifying the molecular evolutionary mechanisms that allow pathogens to specialize to specific plant species and to become more aggressive.

In 2007, Vinatzer sequenced the genome of a Pseudomonas syringae pv. tomato strain using technology from the Virginia Bioinformatics Institute (VBI) at Virginia Tech and funding from the universitys Institute for Biomedical and Public Health Sciences. The tomato pathogen was the first genome to be sequenced on the new Roche GS-FLX machine, which VBI had just purchased with Virginias Commonwealth Research Initiative funding.

That sequence, in addition to other preliminary data, allowed me to develop a hypothesis on the evolution of plant pathogenic bacteria since the beginning of agriculture, Vinatzer said. The hypothesis is that plant pathogenic bacteria evolved from relatively weak pathogens that caused disease in many plants to specialized highly virulent pathogens of single crops after entire fields of the same plant species became available to them in agricultural fields. Importantly, understanding the mechanisms pathogens used to adapt to crops in the past will help us predict how they might change again in the future and allow us to breed or engineer crops for long-lasting disease resistance.

Vinatzers approach combines comparative evolutionary genomics, population genetics, and microbial genetics and leverages the latest advances in the biological sciences and the computer sciences. He is collaborating with Joo Setubal, associate professor and deputy director at VBI.


'/>"/>

Contact: Michael Sutphin
msutphin@vt.edu
540-231-6975
Virginia Tech
Source:Eurekalert

Related biology news :

1. Breakthrough research turns the tide on water-borne pathogen
2. Can interacting pathogens explain disease patterns?
3. Pathogens use previously undescribed mechanism to sabotage host immune system
4. K-State specialist in tick-borne pathogens receives $1.8 million grant
5. New system would use rotating magnetic field to detect pathogens
6. New magnetic separation technique might detect multiple pathogens at once
7. Understanding, combating foodborne pathogens E. coli 0157 and salmonella
8. DOE JGI releases soybean genome assembly to enable worldwide bioenergy research efforts
9. Moss genome shows how plants invaded the land and learned to survive heat and drought
10. WUSTL researchers spearhead key genome initiative
11. DOE JGI Community Sequencing Program delivers first moss genome
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/16/2017)... , May 16, 2017   Bridge ... health organizations, and MD EMR Systems , ... development partner for GE, have established a partnership ... Portal product and the GE Centricity™ products, including ... EMR. These new integrations will ...
(Date:4/24/2017)... Janice Kephart , former 9/11 ... Partners, LLP (IdSP) , today issues the following ... March 6, 2017 Executive Order: Protecting the ... be instilled with greater confidence, enabling the reactivation ... applications are suspended by until at least July ...
(Date:4/18/2017)... 2017  Socionext Inc., a global expert in SoC-based imaging and ... the M820, which features the company,s hybrid codec technology. A demonstration ... Probe, Inc., will be showcased during the upcoming Medtec Japan at ... the Las Vegas Convention Center April 24-27. ... Click here for an ...
Breaking Biology News(10 mins):
(Date:6/27/2017)... ... June 27, 2017 , ... According to a recent report ... do not have negative short- or long-term effects on benthic communities. , ... (PCBs) located at the Puget Sound Naval Shipyard & Intermediate Maintenance Facility in ...
(Date:6/26/2017)... ... 26, 2017 , ... The Workgroup for Electronic Data Interchange (WEDI) , ... in healthcare information exchange and a statutory advisor to the U.S. Department of Health ... Office of the National Coordinator for Health Information Technology, will deliver the keynote at ...
(Date:6/23/2017)... ... June 23, 2017 , ... ... all six of their healthcare job boards. As the largest network of ... therapists, and biotechnicians, DocCafe.com and the MedJobCafe.com Health Network work to match ...
(Date:6/22/2017)... Germany (PRWEB) , ... June 22, 2017 , ... ... is taking over the allergy specialists DST Diagnostische Systeme & Technologien GmbH, thereby ... all know someone who suffers from hay fever, urticaria, asthma, atopic eczema or ...
Breaking Biology Technology: