Navigation Links
Tissue engineering, imaging neuronal circuits featured in Cold Spring Harbor Protocols
Date:4/1/2010

COLD SPRING HARBOR, N.Y. (Thurs., April 1, 2010) The goal of tissue engineering is to recapitulate healthy human organs and tissue structures in culture, and then transplant them into patients, where they are fully integrated. This is a complicated process, and the use of high-throughput imaging systems that allow researchers to directly monitor transplanted tissues in live animals over time is important for improving the culturing and implantation techniques, as well as the design of artificial tissue scaffolds. By using transgenic animals with cell-specific fluorescent reporters, parameters such as tissue perfusion, donor cell survival, and donor-host cell interaction/integration can be observed. In the April issue of Cold Spring Harbor Protocols (http://www.cshprotocols.org/TOCs/toc4_10.dtl), Mary Dickinson and colleagues from the Baylor College of Medicine (http://www.bcm.edu/star/?PMID=3157) present a protocol for the use of "The Mouse Cornea as a Transplantation Site for Live Imaging of Engineered Tissue Constructs." This is a modified version of the classical corneal micropocket angiogenesis assay, which employs it as a live imaging "window" to monitor angiogenic hydrogel tissue constructs. As one of April's featured articles, it is freely available on the journal's website (http://cshprotocols.cshlp.org/cgi/content/full/2010/4/pdb.prot5416).

Neurons are organized into anatomical and functional groups called "circuits". The activity of these circuits is traditionally monitored using conventional electrophysiological techniques. But some cells, such as the submandibular ganglia, are difficult to impale for intracellular recordings. Instead, viral vectors can be used to deliver fluorescent calcium sensors for detecting activity in a living ani
'/>"/>

Contact: David Crotty
crotty@cshl.edu
516-422-4007
Cold Spring Harbor Laboratory
Source:Eurekalert

Page: 1 2

Related biology news :

1. NYSCF fellow lead author on study that derives floor plate tissue from embryonic stem cells
2. Brain tumors: Tissue stem cell turning into tumor stem cell
3. New tissue-hugging implant maps heart electrical activity in unprecedented detail
4. USC researchers identify key mechanism that guides cells to form heart tissue
5. Offering hope for tissue regeneration
6. Scientists discover molecular pathway for organ tissue regeneration and repair
7. UT-Battelle licenses tissue regeneration technologies to NellOne Therapeutics, Inc.
8. $3.75 million grant advances tissue engineering partnership
9. New pathway discovered that may prevent tissue damage resulting from inflammation
10. Supportive materials will help regenerate heart tissue
11. Bioreactor for bone tissue engineering wins professor venture fair
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... what they eat, the Food and Drug Administration (FDA) ... Facts label found on nearly every food product in ... News (C&EN), the weekly news magazine of the ... the fight that has ensued. , Britt Erickson, a ... Nutrition Facts label has remained largely the same for ...
(Date:7/30/2014)... been awarded the Scientific Committee on Antarctic Research,s ... , SCAR, an inter-disciplinary international science body, initiates, ... in the Antarctic region, and on the role ... The organisation also provides scientific advice about Antarctica ... the region. , The medal is open internationally ...
(Date:7/30/2014)... multitude of cells types. Researchers would like to understand how ... cells that make up the organs and other structures of ... chains of sugars that dangle from proteins on surfaces of ... San Diego, has created synthetic molecules that can stand in ... to direct the process, they report in the Journal ...
Breaking Biology News(10 mins):
... day die from breast cancer in the United States. ... taking hormone replacement therapy to avoid the effects of ... Hyder may lead to treatments for breast cancers associated ... international team, found that hormone-therapy-related breast cancer cells have ...
... extensive joint research project among two American Indian tribes ... A. Fulton Schools of Engineering at Arizona State University ... the Phoenix Metropolitan area has received a national environmental ... was awarded a 2013 National Environmental Excellence Award by ...
... new study raises concerns about possible health impacts of very ... international aid agencies are promoting to replace open-fire cooking in ... Science & Technology . Brian Just and colleagues ... on stoves or open fires that burn wood, animal dung ...
Cached Biology News:Joint air toxics research project among tribes, agencies recognized for partnership 2Joint air toxics research project among tribes, agencies recognized for partnership 3
(Date:7/30/2014)...  Decision Resources Group finds that the majority ... the United States believe that ... be the level of savings achievable by their ... cost to patients. Payers plan to leverage preferential ... expectations in order to encourage physician prescribing of ...
(Date:7/30/2014)... Switzerland (PRWEB) July 30, 2014 ... technologies for biologic drug discovery and mammalian cell line ... SURE CHO-Mplus Libraries ™ will be presented at the ... being held, September 8 – 10, 2014 at ... California. , The following abstract will be presented ...
(Date:7/30/2014)... MA (PRWEB) July 30, 2014 BCC ... Global Markets for Enzymes in Industrial Applications , ... reach to nearly $7.1 billion by 2018, registering a ... growth is estimated to be recorded in the detergent ... forecast period. , Enzyme technology has influenced almost every ...
(Date:7/30/2014)... Md. , July 30, 2014 ... components to interrogate biology, but such devices can ... As such, researchers have looked ... in vitro metabolic engineering to characterize ... a chip. New devices are envisioned to recreate ...
Breaking Biology Technology:Surveyed U.S. Payers Expect Cost Savings to MCOs and Patients to be the Strongest Drivers of Biosimilar Uptake 2Surveyed U.S. Payers Expect Cost Savings to MCOs and Patients to be the Strongest Drivers of Biosimilar Uptake 3Selexis SA to Present New Data and a Case Study at IBC’s Cell Line Development and Engineering Conference 2Selexis SA to Present New Data and a Case Study at IBC’s Cell Line Development and Engineering Conference 3Global Market for Industrial Enzymes to Reach Nearly $7.1 Billion by 2018; Detergent Enzyme Market to Record Maximum Growth 2Global Market for Industrial Enzymes to Reach Nearly $7.1 Billion by 2018; Detergent Enzyme Market to Record Maximum Growth 3UMD Researchers Bridge Gap between Microelectronics, Biological Systems 2UMD Researchers Bridge Gap between Microelectronics, Biological Systems 3UMD Researchers Bridge Gap between Microelectronics, Biological Systems 4
... Outcomes in Diabetic Patients, NATICK, Mass. and ... BSX ) today announced one-year results,from the ... OLYMPIA,registry. The first 7,124 patient cohort of the ... TAXUS(R) Liberate(TM) coronary stent,system in complex, real-world patients, ...
... A vaccine against anthrax that is more effective and ... effective in tests in mice and guinea pigs, report University ... Infection and Immunity. , The scientists were able to ... the animals noses with a nanoemulsion a suspension of ...
... NASA clean rooms, where scientists and engineers assemble ... deep mines as unlikely places where scientists have ... species of bacteria uncovered in a recent NASA ... According to Dr. Kasthuri Venkateswaran, who led the ...
Cached Biology Technology:Safety Profile of TAXUS(R) Liberte(TM) Stent System Highlighted in World's Largest Stent Registry 2Safety Profile of TAXUS(R) Liberte(TM) Stent System Highlighted in World's Largest Stent Registry 3Safety Profile of TAXUS(R) Liberte(TM) Stent System Highlighted in World's Largest Stent Registry 4Anthrax vaccine produces immunity with nanoparticles, not needles 2Anthrax vaccine produces immunity with nanoparticles, not needles 3NASA study will help stop stowaways to Mars 2
... V, is used for protein separation and ... system includes both the mini (18 ml) ... harvesting apparatus, cooling finger, electrode chambers, 10 ... syringe, colored protein sample, 2 vent buttons, ...
...
... Labeling Kit - NH2 is primarily used ... immunostaining and cellular proteins for tracing. NH2-Reactive ... succinimidyl group (NHS), and can easily make ... IgG or other proteins without any activation ...
... Lines ,High Quality, Functionally-Validated, Ion Channel Cell ... for having a critical role in nerve ... key function in pain, CNS and the ... been investigated in therapeutic areas, such as ...
Biology Products: