Navigation Links
Tissue engineering, imaging neuronal circuits featured in Cold Spring Harbor Protocols
Date:4/1/2010

COLD SPRING HARBOR, N.Y. (Thurs., April 1, 2010) The goal of tissue engineering is to recapitulate healthy human organs and tissue structures in culture, and then transplant them into patients, where they are fully integrated. This is a complicated process, and the use of high-throughput imaging systems that allow researchers to directly monitor transplanted tissues in live animals over time is important for improving the culturing and implantation techniques, as well as the design of artificial tissue scaffolds. By using transgenic animals with cell-specific fluorescent reporters, parameters such as tissue perfusion, donor cell survival, and donor-host cell interaction/integration can be observed. In the April issue of Cold Spring Harbor Protocols (http://www.cshprotocols.org/TOCs/toc4_10.dtl), Mary Dickinson and colleagues from the Baylor College of Medicine (http://www.bcm.edu/star/?PMID=3157) present a protocol for the use of "The Mouse Cornea as a Transplantation Site for Live Imaging of Engineered Tissue Constructs." This is a modified version of the classical corneal micropocket angiogenesis assay, which employs it as a live imaging "window" to monitor angiogenic hydrogel tissue constructs. As one of April's featured articles, it is freely available on the journal's website (http://cshprotocols.cshlp.org/cgi/content/full/2010/4/pdb.prot5416).

Neurons are organized into anatomical and functional groups called "circuits". The activity of these circuits is traditionally monitored using conventional electrophysiological techniques. But some cells, such as the submandibular ganglia, are difficult to impale for intracellular recordings. Instead, viral vectors can be used to deliver fluorescent calcium sensors for detecting activity in a living ani
'/>"/>

Contact: David Crotty
crotty@cshl.edu
516-422-4007
Cold Spring Harbor Laboratory
Source:Eurekalert

Page: 1 2

Related biology news :

1. NYSCF fellow lead author on study that derives floor plate tissue from embryonic stem cells
2. Brain tumors: Tissue stem cell turning into tumor stem cell
3. New tissue-hugging implant maps heart electrical activity in unprecedented detail
4. USC researchers identify key mechanism that guides cells to form heart tissue
5. Offering hope for tissue regeneration
6. Scientists discover molecular pathway for organ tissue regeneration and repair
7. UT-Battelle licenses tissue regeneration technologies to NellOne Therapeutics, Inc.
8. $3.75 million grant advances tissue engineering partnership
9. New pathway discovered that may prevent tissue damage resulting from inflammation
10. Supportive materials will help regenerate heart tissue
11. Bioreactor for bone tissue engineering wins professor venture fair
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... Shenzhen, July 10, 2014---A team of researchers from The ... have identified a gene of wild soybean linked to ... to grow in saline soil. This study published online ... to unveil novel genomic information for crop improvement. , ... to domestication and human selection, cultivated soybeans have less ...
(Date:7/11/2014)... group members to reduce aggression and gain access to ... grooming activities shows a certain pattern across the day. ... Biology Letters . , Grooming between individuals in ... motives. To be groomed has hygienic benefits and is ... can provide access to infants, mating opportunities and high ...
(Date:7/11/2014)... Sweden, have explored two different ways that allow ... to the formation of oxygen molecules in photosynthesis. ... scientific journal Nature Communications . , "The ... catalysts for water oxidation, which are key components ... storage of solar energy in fuels like hydrogen, ...
Breaking Biology News(10 mins):BGI reports a novel gene for salt tolerance found in wild soybean 2Baboons groom early in the day to get benefits later 2Molecular snapshots of oxygen formation in photosynthesis 2
... team has brought powerful software to the never-ending arms ... and biochemists have developed and laboratory-tested a computer program ... that bacteria use to make natural antibiotics. ... known as the algorithm "K*" (pronounced K Star)-- is ...
... dioxide (CO2) distinguishes itself as the fastest growing greenhouse ... of CO2 emissions depends on our ability to measure ... of the increase. Until the late 1950s ... many questioned whether the industrial revolution and the associated ...
... gene variants associated with an increased incidence of hypertension ... and kidney failure. The report receiving early online release ... in genes for proteins involved with cardiovascular response to ... an association previously seen in animals but not demonstrated ...
Cached Biology News:Duke software dramatically speeds enzyme design 2Duke software dramatically speeds enzyme design 3Carbon accounting from atmospheric measurements -- the aircraft perspective 2Common gene variants increase risk of hypertension, may lead to new therapies 2
(Date:7/10/2014)... On July 9 Prime Minister ... Russia,s first national "Industry" award ... is developing a unique project called MabNext . ... number of innovative drugs based on monoclonal antibodies for ... place at the International Exhibition "Innoprom 2014" in Ekaterinburg. ...
(Date:7/10/2014)... , July 10, 2014 Research ... addition of the "International Photonic Integrated Circuit ... Forecasts to 2019" report to their offering. ... The concept of photonic integration traces its ... century. The promise of photonic integration went unexplored ...
(Date:7/10/2014)... research may help in the fight against terrorism with ... quantities of explosives with the use of light and ... Sensors and Actuators B: Chemical , the researchers describe ... in concentrations as low as 6.3 ppm (parts per ... few minutes. , "Traditionally explosives detection has involved looking ...
(Date:7/10/2014)... the basis of psychiatric disorders has been extremely challenging ... risk but are insufficient to cause disease. Now investigators ... Press journal Cell Stem Cell describe a ... risks interact with other risk factors or environmental exposures ... research pinpoints a genetic variant that may predispose individuals ...
Breaking Biology Technology:Dmitry Medvedev Presented BIOCAD the First National "Industry" Award 2International Photonic Integrated Circuit (Monolithic Integration, Hybrid Integration, Module Integration) Market - Forecasts to 2019 2Detecting trace amounts of explosives with light 2New strategy could uncover genes at the root of psychiatric illnesses 2
... Inc. (Xennex) announced today that it is collaborating ... with access to GeneCards(R) and associated proprietary tools, ... the advanced prototype of GeneCards(R) version 3.0, which ... utilizing GeneCards and the related technology for research ...
... in German . , The enzyme ... able to rapidly ,and efficiently detoxify chemical warfare agents ... subway attacks in 1995. A detailed understanding ,of the ... for efforts aiming to improve their properties. A group ...
... Pharmaceuticals, Inc. (Nasdaq: ANDS ) announced today ... on Thursday, April 23, 2009, after the U.S. financial ... on Thursday, April 23, 2009 at 5:00 p.m. Eastern ... results and highlights and to provide an update on ...
Cached Biology Technology:Xennex Inc. Providing Satoris Inc. with Latest GeneCards(R) Tools for Characterization of Protein Biomarkers Associated With Neurological Conditions 2Xennex Inc. Providing Satoris Inc. with Latest GeneCards(R) Tools for Characterization of Protein Biomarkers Associated With Neurological Conditions 3Structure of enzyme against chemical warfare agents determined 2Anadys Pharmaceuticals to Report First Quarter 2009 Financial Results 2
Rabbit monoclonal [EP881Y] to EEF2K ( Abpromise for all tested applications). Antigen: Synthetic peptide corresponding to residues in the C-terminal of human EEF2K. Entrez GeneID: 29904 S...
Weinreb Linker...
Anti-Human Factor XIII HRPO (Polyclonal) (sheep IgG)...
Request Info...
Biology Products: