Navigation Links
Tissue engineering, imaging neuronal circuits featured in Cold Spring Harbor Protocols
Date:4/1/2010

COLD SPRING HARBOR, N.Y. (Thurs., April 1, 2010) The goal of tissue engineering is to recapitulate healthy human organs and tissue structures in culture, and then transplant them into patients, where they are fully integrated. This is a complicated process, and the use of high-throughput imaging systems that allow researchers to directly monitor transplanted tissues in live animals over time is important for improving the culturing and implantation techniques, as well as the design of artificial tissue scaffolds. By using transgenic animals with cell-specific fluorescent reporters, parameters such as tissue perfusion, donor cell survival, and donor-host cell interaction/integration can be observed. In the April issue of Cold Spring Harbor Protocols (http://www.cshprotocols.org/TOCs/toc4_10.dtl), Mary Dickinson and colleagues from the Baylor College of Medicine (http://www.bcm.edu/star/?PMID=3157) present a protocol for the use of "The Mouse Cornea as a Transplantation Site for Live Imaging of Engineered Tissue Constructs." This is a modified version of the classical corneal micropocket angiogenesis assay, which employs it as a live imaging "window" to monitor angiogenic hydrogel tissue constructs. As one of April's featured articles, it is freely available on the journal's website (http://cshprotocols.cshlp.org/cgi/content/full/2010/4/pdb.prot5416).

Neurons are organized into anatomical and functional groups called "circuits". The activity of these circuits is traditionally monitored using conventional electrophysiological techniques. But some cells, such as the submandibular ganglia, are difficult to impale for intracellular recordings. Instead, viral vectors can be used to deliver fluorescent calcium sensors for detecting activity in a living ani
'/>"/>

Contact: David Crotty
crotty@cshl.edu
516-422-4007
Cold Spring Harbor Laboratory
Source:Eurekalert

Page: 1 2

Related biology news :

1. NYSCF fellow lead author on study that derives floor plate tissue from embryonic stem cells
2. Brain tumors: Tissue stem cell turning into tumor stem cell
3. New tissue-hugging implant maps heart electrical activity in unprecedented detail
4. USC researchers identify key mechanism that guides cells to form heart tissue
5. Offering hope for tissue regeneration
6. Scientists discover molecular pathway for organ tissue regeneration and repair
7. UT-Battelle licenses tissue regeneration technologies to NellOne Therapeutics, Inc.
8. $3.75 million grant advances tissue engineering partnership
9. New pathway discovered that may prevent tissue damage resulting from inflammation
10. Supportive materials will help regenerate heart tissue
11. Bioreactor for bone tissue engineering wins professor venture fair
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... the fish world, are the ideal animal in which ... moved from the ocean into tens of thousands of ... changing their skeleton to adapt to the new environment. ... sticklebacks now have turned up one of the genes ... change in that gene,s regulation in a freshwater population ...
(Date:9/17/2014)... health care to reproductive technologies, the justice and ... of people to identify key issues, articulate their ... find the most defensible ways forward. But what ... societal conversations?, The Hastings Center and the Presidential ... teamed up to publish a series of essays ...
(Date:9/17/2014)... started in 2000 as an EC-FP5 four-year project, delivering ... steady progress and successful participations in several EC projects, ... Observation Network project (EU BON), to increase the ... and to extend the general dissemination of the Fauna ... has applied its novel e-Publishing tools to prepare ...
Breaking Biology News(10 mins):Counting fish teeth reveals regulatory DNA changes behind rapid evolution, adaptation 2Counting fish teeth reveals regulatory DNA changes behind rapid evolution, adaptation 3Why bioethics literacy matters 2Why bioethics literacy matters 3Contributions on Fauna Europaea: Data papers as innovative model on expert involvement 2
... Mich.---In the mating game, some female mites are mightier than ... the Russian Academy of Sciences suggests. The evidence comes, in ... In a paper published March 1 in the ... and Ekaterina Sidorchuk describe an extinct mite species in which ...
... look at possible health effects of the Gulf of Mexico,s ... begins today in towns across Louisiana, Mississippi, Alabama, and Florida. ... the largest health study of its kind ever conducted among ... comprehensive federal response to the Deepwater Horizon oil spill. The ...
... University of Maryland School of Medicine researchers have ... open doors to new, more effective treatments for excessive ... in the brain, GABA receptors and toll-like receptor 4 ... weeks in rodents that had been bred and trained ...
Cached Biology News:Mating mites trapped in amber reveal sex role reversal 2NIH launches largest oil spill health study 2University of Maryland School of Medicine study identifies genes associated with binge drinking 2University of Maryland School of Medicine study identifies genes associated with binge drinking 3University of Maryland School of Medicine study identifies genes associated with binge drinking 4
(Date:9/18/2014)... YARDLEY , Pennsylvanie, 18 septembre 2014 ... Lyon en 1974, a été ... à compléter les évaluations cliniques traditionnelles par ... Reported Outcomes) et sur les impacts économiques ... http://photos.prnewswire.com/prnh/20140618/119365 A cours ...
(Date:9/18/2014)... , Sept. 18, 2014   Sigma-Aldrich ... it has entered into a new gene editing ... School,s Vector Core. Under the partnership, Sigma-Aldrich will ... experimental design consultation, and dedicated gene editing bioinformaticians. ... gene editing-based research at the U-M Medical School. ...
(Date:9/18/2014)... September 18, 2014 OMICS Group ... globe to participate in the ‘Open Access Week’ ... to OMICS Group Pharma Journals from ... of the fastest emerging Sciences, accelerating with a ... services across the globe. The industry is gearing ...
(Date:9/18/2014)... MA (PRWEB) September 18, 2014 ... Molecule Sequencing (tSMS™) technology, announced today the closing ... of investment, led by Genomic Diagnostic Technologies, will ... and diagnostic applications. , Founded in March 2013 ... and Bioinformatics Analyst at Helicos BioSciences, SeqLL has ...
Breaking Biology Technology:1974 - 2014 - Mapi fête ses 40 ans 2Sigma-Aldrich, University of Michigan Medical School Establish CRISPR Core Lab Partnership 2Sigma-Aldrich, University of Michigan Medical School Establish CRISPR Core Lab Partnership 3Sigma-Aldrich, University of Michigan Medical School Establish CRISPR Core Lab Partnership 4Pharma and Omics Journals to Address Global Challenges during Open Access Week 2Pharma and Omics Journals to Address Global Challenges during Open Access Week 3SeqLL Closes Series-A Funding Round for Expansion of Single Molecule Sequencing 2
... Berkeley -- Scientists who dream of shrinking computers to ... building block for both processor and memory, yet setting ... has been a challenge. , Now, University of California, ... a single atom, moving one step closer to quantum ...
... Sept. 13 Halozyme Therapeutics,Inc. (Nasdaq: HALO ), ... extracellular matrix, today announced,that Jonathan Lim, MD, Halozyme,s President ... Global Life Sciences Conference to be held at,the Grand ... 2007 at 9:00,a.m. Eastern time (6:00 a.m. Pacific time). ...
... 13 Cadence Pharmaceuticals,Inc. (Nasdaq: CADX ... and commercializing proprietary product candidates principally,for use ... Malvina Laudicina has,joined Cadence,s management team as ... will lead the regulatory and quality assurance,activities ...
Cached Biology Technology:Physicists pin down spin of surface atoms 2Physicists pin down spin of surface atoms 3Halozyme Therapeutics to Present at UBS 2007 Global Life Sciences Conference 2Cadence Pharmaceuticals Names Malvina Laudicina Vice President of Regulatory Affairs and Quality Assurance 2Cadence Pharmaceuticals Names Malvina Laudicina Vice President of Regulatory Affairs and Quality Assurance 3
... PCR Purification Kits provide rapid and efficient ... PCR products, and salts from PCR products ... provides two Binding Buffer options for ... can be performed in either single column ...
Mus musculus junctophilin 2 (Jph2) Antigen: Recombinant Protein...
... Cloning Kits for Sequencing allow 5-minute cloning and ... TOPO Cloning vectors with primer sites located as ... product insertion site. This minimizes the amount of ... reaching the sequence of your insert.vectors are available. ...
2.0 GHz Compaq Computer with 512 MB RAM, 32 MB AGP Graphics Card, 40 GB Hard Drive, 1 Serial Port & Open PCI Slot, Windows 2000 OS, MS Office, CD Read/Writer and 18 Flat Panel Monitor...
Biology Products: