Navigation Links
Tips on how to build a better home for biological parts
Date:7/16/2008

raduate students engineer novel biological systems starting from BioBricks, the parts documented in the Registry of Standard Biological Parts. The BioBrick is an emerging standard for DNA fragments that facilitates the assembly of biological parts into more complex devices and systems by using a standardized fabrication process. The entire collection of parts associated with the Registry is distributed to all teams enrolled in the iGEM competition. The iGEM participants are expected to return the designs they made to the Registry at the end of the competition.

The new study by VBI researchers not only examined the information content of the Registry database but also the collection of publicly available DNA sequences or clones (BioBricks) that are used to make the biological devices and systems. The analysis of the Registry database and the associated DNA clones identified several key needs where improvements could be made. These included the following: (a) to distinguish basic parts and composite parts that can be broken down into smaller parts; (b) to set curation standards to document the sequences of basic parts by associating them with entries in bioinformatic or bibliographic databases; (c) to define and implement quality control standards that ensure the integrity of DNA clones; and (d) to provide editorial policies that could help build registries of biological parts with high-value and high-quality content.

Peccoud concluded: "The Registry of Standard Biological Parts has been a pioneering experiment for the synthetic biology community and lessons should be learned to improve this resource and design the next-generation registries of biological parts. This bottom-up approach to biology raises a number of challenging theoretical questions. Defining what is a biological part, for example, remains a problem that the entire synthetic biology community needs to solve. In this respect, recent initiatives led by the BioBrick foundation and oth
'/>"/>

Contact: Barry Whyte
whyte@vbi.vt.edu
540-231-1767
Virginia Tech
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Building blocks of life
2. Researchers create system to build transplant tissue
3. New approach builds better proteins inside a computer
4. Rebuilding the evolutionary history of HIV-1 unravels a complex loop
5. Building blocks of life formed on Mars
6. Building disease-beating wheat
7. CSIC and UAB will build the most advanced superconductor cable for electricity network
8. GM, Coskata partnership builds on Oklahoma State University biofuels research
9. Building the future -- 21st century nano tools to repair the nervous system
10. Scientists rebuild ancient proteins to reveal primordial Earths temperature
11. International workshop to address capacity building for rainforest leaders
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... seedless watermelon, salmon, and strawberries all have in common? ... sets of chromosomes and are diploid, these organisms are ... of chromosomesseedless watermelon and salmon have 3 and 4 ... While this might seem surprising, in fact most plant ... discovered over a century ago, but only recently, with ...
(Date:9/30/2014)... environmental scientists and engineers, led by Clemson University ... $5.25 million grant from the U.S. Department of ... make a direct positive impact on South Carolina ... of radioactive contaminants. , "Understanding the scientific and ... environmental aspects of nuclear technologies is imperative if ...
(Date:9/30/2014)... release is available in German . ... among the most expensive foods in the world. Because they ... them. But the distinctive smell of truffles is not only ... scientists under the direction of the Goethe University Frankfurt have ... by soil bacteria which are trapped inside truffle fruiting bodies. ...
Breaking Biology News(10 mins):Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 2Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 3Gene doubling shapes the world: Instant speciation, biodiversity, and the root of our existence 4Researchers get $5.25 million to advance nuclear technologies in South Carolina 2On the trail of the truffle flavor 2
... altitude isn,t the only thing that dropstheir blood pressure ... in up to half of those astronauts on short-term ... astronauts after long-term missions (four to six months). A ... Journal ( http://www.fasebj.org ) solves the biological mystery ...
... Elbe are not a common sight. Yet 1.8 million years ... mega-fauna such as woolly mammoths and giant cave bears bestrode ... that the changing climate during the Pleistocene Era may have ... them to warmer climes. "Species of hippo ranged across ...
... Data publishers should have the option of submitting ... discussion paper commissioned by the Global Biodiversity Information Facility ... of recommendations made by Mark Costello and co-authors in ... advancing biodiversity data publication , freely available for ...
Cached Biology News:Why astronauts experience low blood pressure after returning to Earth from space 2Did the changing climate shrink Europe's ancient hippos? 2Peer review option proposed for biodiversity data 2
(Date:10/1/2014)... 1, 2014 Pfanstiehl has announced the ... manufactured in the USA ... been recognized for playing a key role in ... of evidence that media supplementation with mannose can ... glycosylation," according to Dr. Christopher Wilcox , ...
(Date:10/1/2014)... 2014 The participants committed to not ... spending their own time adjusting, tweaking and testing virtual ... were ready for judging. , “I enjoyed being involved ... leader. “The entries showed a commendable range exploring ... of the print medium and the creativity of the ...
(Date:10/1/2014)... CA (PRWEB) September 30, 2014 ... user-friendly, cost-effective tools to address sales, training and ... has developed innovative mobile applications to turn ... outlining the agency’s latest customized mobile app creations, ... http://www.studiopmg.com/work . , In partnership with Toyota, StudioPMG ...
(Date:10/1/2014)... MA (PRWEB) September 30, 2014 ... SoundConnect announces four new-hosted collaboration bundles ... bundles deliver high quality conferencing experiences for low, ... packages to choose from, businesses have optimized solutions ... bundled solutions include audio only minutes (1K, ...
Breaking Biology Technology:Pfanstiehl Launches cGMP-produced Mannose for Cell Culture Media Optimization & Glycoprotein Biosynthesis 2Array Architects Challenges Staff to Create with 3D Printer 2Digital Agency Studio PMG Launches New Case Studies on Website 2SoundConnect Launches New Audio, Web and Video Bundles 2
... heard about the merits of electronic medical records and other healthcare ... make of the industry's electronic push? Marty Preizler, president and CEO ... much the same way and he explains why in Part I ... of the interview are as follows: , , WTN: ...
... - Jan Eddy, an entrepreneur who built and rebuilt ... Seize the Day award, which will be presented June 13 ... ,Eddy, who has overcome business and personal health challenges in ... conference luncheon at the Milwaukee Hyatt Regency. , ,Eddy, who ...
... the Milwaukee Brewers have used their minor-league system ... to join the major leagues of venture investing by building ... milestone with the news that Wisconsin has surpassed the $100 ... new report compiled by NorthStar Economics , the ...
Cached Biology Technology:Visions: Preizler offers insurer's perspective on healthcare IT 2Visions: Preizler offers insurer's perspective on healthcare IT 3Visions: Preizler offers insurer's perspective on healthcare IT 4Visions: Preizler offers insurer's perspective on healthcare IT 5Visions: Preizler offers insurer's perspective on healthcare IT 6Visions: Preizler offers insurer's perspective on healthcare IT 7Wisconsin building toward the major leagues of venture capital 2Wisconsin building toward the major leagues of venture capital 3
The PxE Thermal Cycler (PxE) is a licensed 96 well PCR machine, developed to provide all fundamental features for value for money thermal cycling....
PxE thermal Cycler. 0.5ml block holds 48 0.5 ml tubes or 96 0.3 ml tubes. Adjustable height heated lid. Outstanding uniformity. Advanced control algorithms for reduced reaction times. User frien...
0.2ml Gradient Block MBSR. Robot compatible block ejection mechanism. Stackable. (96 well block - holds 1 plate 0.2ml x 96 well plate)...
A Highly Purified, Cost-Effective Taq DNA Polymerase...
Biology Products: