Navigation Links
Tips on how to build a better home for biological parts
Date:7/16/2008

raduate students engineer novel biological systems starting from BioBricks, the parts documented in the Registry of Standard Biological Parts. The BioBrick is an emerging standard for DNA fragments that facilitates the assembly of biological parts into more complex devices and systems by using a standardized fabrication process. The entire collection of parts associated with the Registry is distributed to all teams enrolled in the iGEM competition. The iGEM participants are expected to return the designs they made to the Registry at the end of the competition.

The new study by VBI researchers not only examined the information content of the Registry database but also the collection of publicly available DNA sequences or clones (BioBricks) that are used to make the biological devices and systems. The analysis of the Registry database and the associated DNA clones identified several key needs where improvements could be made. These included the following: (a) to distinguish basic parts and composite parts that can be broken down into smaller parts; (b) to set curation standards to document the sequences of basic parts by associating them with entries in bioinformatic or bibliographic databases; (c) to define and implement quality control standards that ensure the integrity of DNA clones; and (d) to provide editorial policies that could help build registries of biological parts with high-value and high-quality content.

Peccoud concluded: "The Registry of Standard Biological Parts has been a pioneering experiment for the synthetic biology community and lessons should be learned to improve this resource and design the next-generation registries of biological parts. This bottom-up approach to biology raises a number of challenging theoretical questions. Defining what is a biological part, for example, remains a problem that the entire synthetic biology community needs to solve. In this respect, recent initiatives led by the BioBrick foundation and oth
'/>"/>

Contact: Barry Whyte
whyte@vbi.vt.edu
540-231-1767
Virginia Tech
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Building blocks of life
2. Researchers create system to build transplant tissue
3. New approach builds better proteins inside a computer
4. Rebuilding the evolutionary history of HIV-1 unravels a complex loop
5. Building blocks of life formed on Mars
6. Building disease-beating wheat
7. CSIC and UAB will build the most advanced superconductor cable for electricity network
8. GM, Coskata partnership builds on Oklahoma State University biofuels research
9. Building the future -- 21st century nano tools to repair the nervous system
10. Scientists rebuild ancient proteins to reveal primordial Earths temperature
11. International workshop to address capacity building for rainforest leaders
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... A new study from UC San Francisco is the ... stressors accumulate overtime and accelerate cellular aging, these negative ... exercising and sleeping well. , "The study participants ... telomere shortening than the ones who didn,t maintain healthy ... said lead author Eli Puterman, PhD, assistant professor in ...
(Date:7/28/2014)... team of researchers led by the University of Arizona ... The genetic information will enhance scientists, and agriculturalists, understanding ... as enable the development of new rice varieties that ... to help solve global hunger challenges. , The paper, ... ) and evidence for independent domestication," was published online ...
(Date:7/28/2014)... have pinpointed a mechanism in part of the brain that ... it to both type 1 and type 2 diabetes. The ... Proceedings of the National Academies of Sciences . , ... a part of the hypothalamus known as the ventromedial nucleus ... glucose levels in the blood," said lead author Sabrina Diano, ...
Breaking Biology News(10 mins):Healthy lifestyle may buffer against stress-related cell aging, study says 2Generating a genome to feed the world: UA-led team sequences African rice 2Generating a genome to feed the world: UA-led team sequences African rice 3Generating a genome to feed the world: UA-led team sequences African rice 4Glucose 'control switch' in the brain key to both types of diabetes 2
... LA JOLLA, CA October 29, 2010 For ... has revealed the first-ever pictures of the formation of cells, ... on its own, the work could open new pathways for ... in ribosome formation. In addition, the techniques developed in the ...
... (NTU) and Imperial College London today signed an official ... initiative was previously announced by Prime Minister Lee Hsien ... Presently, the working name for the school is "Imperial ... To start in 2013, ICNMS will be positioned to ...
... A new study by University of North Carolina at ... anorexia nervosa are much more likely to have both unplanned ... serious eating disorder. These results may be driven by ... get pregnant because they are either not having menstrual periods ...
Cached Biology News:Scripps Research team 'watches' formation of cells' protein factories for first time 2Scripps Research team 'watches' formation of cells' protein factories for first time 3Imperial and NTU's new medical school aspires to be global health care role model 2Imperial and NTU's new medical school aspires to be global health care role model 3Imperial and NTU's new medical school aspires to be global health care role model 4Women with anorexia nervosa more likely to have unplanned pregnancies 2
(Date:7/29/2014)... 2014 Quorum Review IRB, the ... awarded accreditation by the International Association of ... Six Sigma Deployment Program. The citation recognizes robust ... , Quorum’s Lean Six Sigma program was evaluated ... designation. The designation is a public statement of ...
(Date:7/29/2014)... San Diego, CA (PRWEB) July 29, 2014 ... added to Pipette.com’s centrifugation product selection. Eppendorf 5427 R ... reverse engineering, and DNA – it is targeted towards ... the Eppendorf Centrifuge 5427 R as it compliments their ... as their Eppendorf line of microcentrifuge tubes, PCR tubes, ...
(Date:7/29/2014)... Lehigh Acres, FL (PRWEB) July 29, 2014 ... (FIB) ex situ lift out specimen preparation solutions, has ... and Trademark Office for specimen manipulation methods incorporating a ... Patent 8,740,209. This is the second company patent ... Lucille A. Giannuzzi. , These complementary patents ...
(Date:7/28/2014)... The Workgroup for Electronic Data Interchange (WEDI), ... health IT to create efficiencies in healthcare information exchange, ... has developed an issue brief titled, “What is ... HPID Workgroup, a part of WEDI’s Strategic National HPID ... and Medicaid Services (CMS) to identify common misuse of ...
Breaking Biology Technology:Quorum Review IRB Accredited by IASSC for Lean Six Sigma Deployment Program 2Quorum Review IRB Accredited by IASSC for Lean Six Sigma Deployment Program 3International Pipette Distributor, Pipette.com Announces the Addition of the Eppendorf Centrifuge 5427 R to Their Product Portfolio 2EXpressLO LLC Granted Second U.S. Patent for Innovative Specimen Preparation Methods 2WEDI’s HPID Workgroup Announces Release of Issue Brief: “What is the Difference Between a Health Plan and Payer?” 2
... May 15 Senetek PLC (OTC Bulletin Board: SNKTY), ... technologies that target the science of healthy aging, announced ... developments is now available by calling 877-SENETEK in the ... "We are pleased to provide this service to our ...
... Genetics, Inc. (NYSE Amex: ILI ) announced today ... Forum on Wednesday, May 20, 2009, at 2:40 p.m. EDT ... GA. Lewis H. Bender, Chief Executive Officer, will present an ... available genetic tests and recent milestones. "Genetic testing and personalized ...
... N.C., May 15 PRA International, a ... the annual meeting for the International Society for Pharmacoeconomics ... Experts from PRA,s Late Phase Services group will ... PRA,s capabilities. PRA,s Late Phase Services group supports ...
Cached Biology Technology:Senetek PLC Investor Hotline Goes Live 2Interleukin Genetics to Present at the 2009 BIO Business Forum 2PRA International Participating in Pharmacoeconomics and Outcomes Research Conference 2
... is most widely used in combination ... differentially stain nucleic acids following polyacrylamide ... solution, Pyronin Y stains RNA red, ... Chem comp: Dye content ...
... The loxP-cm-loxP cassette is ... prokaryotic cells. The prokaryotic promoter ... resistance is a slightly modified version ... higher transcription efficiency than the generally ...
... Agencourt AMPure is a ... that requires no sample transfer, ... efficiently purifies small and large ... or 384-well microplates. Agencourt AMPure ...
... is a magnetic bead-based PCR ... sample transfer, centrifugation or filtration ... and large PCR extension products ... Agencourt AMPure can easily be ...
Biology Products: