Tips from the journals of the American Society for Mi... (however they lack the RNA required for v...)

Tips from the journals of the American Society for Microbiology

Date:6/19/2009

however, they lack the RNA required for virus replication.

In this study researchers generated VLPs from the structural proteins of the 1918 H1N1 virus and compared their ability to protect mice and ferrets against a reconstructed 1918 virus and the highly pathogenic avian H5N1 virus that was isolated from a fatal human case. When immunized twice intranasally with H1N1 VLPs mice were highly protected against a lethal challenge with both the 1918 and H5N1 virus. In contrast, mice receiving two intramuscular immunizations of 1918 VLPs were only protected against the 1918 viral challenge. Mucosal vaccination with 1918 VLPs induced higher levels of cross-reactivity in mice and complete survival in ferrets challenged with a lethal dose of the H5N1 virus. Only a 50% survival rate was noted in intramuscularly immunized animals.

"These results suggest a strategy of VLP vaccination against a pandemic virus and one that stimulates heterotypic immunity against an influenza virus strain with threatening pandemic potential," say the researchers.

(L.A. Perrone, A. Ahmad, V. Veguilla, X. Lu, G. Smith, J. M. Katz, P. Pushko, T.M. Tumpey. 2009. Intranasal vaccination with 1918 influenza virus-like particles protects mice and ferrets from lethal 1918 and H5N1 influenza virus challenge. Journal of Virology, 83. 11: 5726-5734.)

'/>"/>

Contact: Carrie Slijepcevic
cslijepcevic@asmusa.org
American Society for Microbiology
Source:Eurekalert

0

GOOD

Page: 1 2 3 4
Related biology news :

1. Tips from the Journals of the American Society for Microbiology
2. ESA celebrates 100 years of insect science journals
3. Springer and the New York Botanical Garden Press join forces to publish botanical journals
4. 200 journals join in theme issues on poverty and human development
5. Tips from the Journals of the American Society for Microbiology
6. Humana Press journals now available on SpringerLink
7. Tips from the Journals of the American Society for Microbiology
8. Tips from the Journals of the American Society for Microbiology
9. Mycotoxin Research joins Springers life sciences journals program
10. Oxford Journals and the International Society for Computational Biology announce new partnership
11. Springer and Senckenberg society to collaborate on life sciences and geosciences journals

Post Your Comments:

(Date:12/16/2009)... Va., Dec. 9 CSC (NYSE: ... the American Association for Laboratory Accreditation awarded ... (ISO/IEC) 17025:2005 accreditation to the company,s Test ... Identity Labs located in Fairmont, W.Va. The ... laboratory in the world to achieve this ...

(Date:12/15/2009)... The 2009 Frost & Sullivan European Border ... Sagem Securite (Safran Group) for its innovative ... the company,s expertise in advanced biometric technology ... value-added products to end users. ,, ... Securite has been involved in delivering identification ...

(Date:12/15/2009)... When treating devastating brain diseases such as Alzheimer,s ... to find something to help a patient. , But ... the vast majority of patients with ataxia disabling ... , University of Florida neurologists are trying to change ... grant from the National Institute of Neurological Disorders and ...

[0] CSC's Identity Management and Biometric Test Lab Achieves ISO/IEC 17025 Accreditation [0] Frost & Sullivan Recognises Sagem Securite for its Innovative Automated Border Control Systems [0] UF to lead national effort to help patients with rare brain disease

... Vegetables , Protozoa found on lettuce and ... to their survival on produce surfaces say researchers ... Safety and Microbiology Research Unit, Albany, California. ... issue of the journal Applied and Environmental Microbiology. ...

... Papers presented at the 1st European Lung Cancer Conference, ... (ESMO) and the International Association for the Study of ... that common viruses may contribute to the development of ... by far the most important factor that contributes to ...

... The vaccinia virus has a problem: it is a giant ... infiltrate a cell and reproduce. Professor Ari Helenius and Postdoc ... discovered what this strategy is. In the process, they stumbled ... , In order to infiltrate a cell, the ...

Other Biology News:Tips from the Journals of the American Society for Microbiology 2 Tips from the Journals of the American Society for Microbiology 3 Tips from the Journals of the American Society for Microbiology 4 Viruses may play a role in lung cancer development 2 A step forward in virology 2 A step forward in virology 3

Tips from the Journals of the American Society for Microbiology Viruses may play a role in lung cancer development A step forward in virology

(Date:12/15/2009)... WILMINGTON, Del. and CHARLOTTESVILLE, Va., Dec. 15 ... ) and the University of Virginia (UVa) ... entered into a strategic research collaboration to ... coronary artery disease (CAD) with a secondary ... (Logo: http://www.newscom.com/cgi-bin/prnh/20091027/PH99766LOGO ) ,, The ...

(Date:12/15/2009)... The International Society for Medical Publication Professionals (ISMPP) ... to accept abstracts for its 6th Annual Meeting, ... 19-21, 2010. This marks the first time that ... organization to submit an abstract to this increasingly ... EST, January 15, 2010. For submission details, please ...

(Date:12/15/2009)... PHILADELPHIA and LONDON, Dec. 15 ... Thomson Pharma ® has become the first ... trial protocol and outcome information. This highly anticipated ... Pharma customers this month. ,, ... trial intelligence from registries, publications, press releases, conferences, ...

(Date:12/14/2009)... Dec. 14 Array BioPharma Inc. (Nasdaq: ... ) today announced that they entered into an ... small-molecule glucokinase activator program, including ARRY-403, currently being ... patients with Type 2 diabetes. ,, ... receive an upfront payment of $60 million and ...

Breaking Biology Technology:AstraZeneca and the University of Virginia Sign Strategic Research Collaboration to Develop Novel Treatments for Cardiovascular Disease 2 AstraZeneca and the University of Virginia Sign Strategic Research Collaboration to Develop Novel Treatments for Cardiovascular Disease 3 The International Society for Medical Publication Professionals Announces Call for Abstracts for Its 6th Annual Meeting 2 The International Society for Medical Publication Professionals Announces Call for Abstracts for Its 6th Annual Meeting 3 Thomson Reuters is First to Offer Fully Integrated Pipeline and Clinical Trials 2 Array BioPharma and Amgen Partner in Type 2 Diabetes 2 Array BioPharma and Amgen Partner in Type 2 Diabetes 3 Array BioPharma and Amgen Partner in Type 2 Diabetes 4 Array BioPharma and Amgen Partner in Type 2 Diabetes 5 Array BioPharma and Amgen Partner in Type 2 Diabetes 6 Array BioPharma and Amgen Partner in Type 2 Diabetes 7

[0] AstraZeneca and the University of Virginia Sign Strategic Research Collaboration to Develop Novel Treatments for Cardiovascular Disease [0] The International Society for Medical Publication Professionals Announces Call for Abstracts for Its 6th Annual Meeting [0] Thomson Reuters is First to Offer Fully Integrated Pipeline and Clinical Trials [0] Array BioPharma and Amgen Partner in Type 2 Diabetes

... S*BIO Pte Ltd, a cancer therapeutics,company, today announced ... led by Bio*One Capital and new investor Aravis ... Fund advised by,Adamant Biomedical Investments AG and Zurcher ... fund the development efforts of its,two lead compounds, ...

... SYDNEY, Australia, Oct. 19 /Xinhua-PRNewswire-FirstCall/ --,Pharmaceutical company ... it had received approval to market Aridol ... Aridol is indicated for measuring airway hyperresponsiveness ... countries - Denmark, Finland, France, Germany,Greece, Ireland, ...

... Mattel Children,s Hospital UCLA today announced the launch ... explore the future of personalized medicine for children, ... is one of the world,s first dedicated solely ... , "Why develop a nanopediatrics program? Because children ...

Other Biology Technology:S*BIO Completes US$26 Million Equity Financing 2 S*BIO Completes US$26 Million Equity Financing 3 S*BIO Completes US$26 Million Equity Financing 4 Pharmaxis Aridol Approved for Sale in Switzerland 2 Mattel Children's Hospital UCLA launches program in nanopediatrics 2

S*BIO Completes US$26 Million Equity Financing Pharmaxis Aridol Approved for Sale in Switzerland Mattel Children's Hospital UCLA launches program in nanopediatrics

... Technology's family of light scattering instruments. The ... chromatograph and enables you to get multi-angle ... HTmD is easily installed in the oven ... 2000 device and enables you to get ...

...

... White solid. PROTECT FROM LIGHT. PACKAGED ... compound that acts as a selective, ... PTP1B (IC 50 = 4 ... 403 and PTP1B 298 , ...

... White walled plates enhance luminescent signals ... fluorescence,• Not treated (or medium binding) ... and binds biomolecules through passive interactions,• ... of large molecules, such as antibodies, ...

Biology Products:

High Temperature miniDAWN (HTmD) for 150C, PL220C, Alliance 2000 from Wyatt Technology Sf21 Insect Cells from BD Biosciences Pharmingen PTP1B Inhibitor from Calbiochem CORNING 1536 WELL PLATE,2UL,WHITE,NON-TREATED,NON STERILE from Sigma-Aldrich

Tips from the journals of the American Society for Mi...(however they lack the RNA required for v...)