Navigation Links
Tips from the Journals of the American Society for Microbiology
Date:11/19/2009

One of the main contributing factors to dental cavities is overpopulation of acid-producing bacteria in the oral cavity that causes localized destruction of compromised dental hard tissue. Due to the episodic nature of cavities, long-term benefits of periodic treatments administered during routine office visits are minimal. Other delivery systems developed to maintain drug concentrations, including bioadhesive tablets, patches, films, and gels, aren't very effective on the tooth surface and often cause irritation resulting in poor patient compliance. Emphasis on the need for therapeutic strategies that target the bacterial aspect of the disease and a delivery platform that would maintain the drug concentration on the tooth surface is warranted.

In the study tooth-binding micelles (molecular particles) were developed and encapsulated with farnesol, an antimicrobial recently found to be effective against the cavity causing bacterium Streptococcus mutans UA159. When tested on a model tooth surface the micelles were able to swiftly bind and gradually release the encapsulated farnesol. Additionally, biofilm inhibition studies of the farnesol-containing tooth-binding micelles demonstrated that they were able to inhibit S. mutans UA159 at much higher levels than untreated blank control micelles.

"A tooth-binding micelle delivery platform for the prevention and treatment of dental carries has been designed and prepared in this study," say the researchers. "It is anticipated that the tooth-binding micelles have the potential to be formulated into mouth rinses that may have the merits of simple application, cultural acceptance, and improved patient compliance."

(F. Chen, X.M. Liu, K.C. Rice, X. Li, F. Yu, R.A. Reinhardt, K.W. Bayles, D. Wang. 2009. Tooth-binding micelles for dental carries prevention. Antimicrobial Agents and Chemotherapy, 53. 11: 4898-4902.)


'/>"/>

Contact: Carrie Slijepcevic
cslijepcevic@asmusa.org
American Society for Microbiology
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Tips from the Journals of the American Society for Microbiology
2. ESA celebrates 100 years of insect science journals
3. Springer and the New York Botanical Garden Press join forces to publish botanical journals
4. 200 journals join in theme issues on poverty and human development
5. Tips from the Journals of the American Society for Microbiology
6. Humana Press journals now available on SpringerLink
7. Tips from the Journals of the American Society for Microbiology
8. Tips from the Journals of the American Society for Microbiology
9. Mycotoxin Research joins Springers life sciences journals program
10. Oxford Journals and the International Society for Computational Biology announce new partnership
11. Springer and Senckenberg society to collaborate on life sciences and geosciences journals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2015)... JOSE, Calif. , June 24, 2015 /PRNewswire/ ... developer of human interface solutions, today announced that ... sensor to provide secure authentication for its latest ... recently reached more than 200 million shipments of ... with Sharp reinforces Synaptics, strength, scalability and leadership ...
(Date:6/23/2015)... 23, 2015   MedNet Solutions , an ... entire spectrum of clinical research, is pleased to ... , the company,s intuitive, flexible and affordable cloud-based ... 2015 Stevie® Award by the American Business ... Website category.  The American Business Awards are considered ...
(Date:6/23/2015)... Fla. , June 23, 2015 /PRNewswire/ ... management and authentication solutions, today announced enhanced functionality ... multi-factor authentication solution.  The enhancements build on ... of the DigitalPersona Altus platform and provide ... compatibility. In today,s environment of ...
Breaking Biology News(10 mins):Synaptics Brings Natural ID Technology to Sharp's Newest Flagship Smartphone 2MedNet Solutions' iMedNet eClinical Wins Silver Stevie Award 2Crossmatch Releases Enhanced DigitalPersona Altus Advanced Authentication Functionality 2
... Medical Center scientists have demonstrated a new technology that ... E. coli bacteria. , The unique technology uses a ... sensing system that also includes a silicon chip and ... published an article on the technology in its February ...
... caused by agricultural run-off and pollution, could spark the development ... species with extinction, according to a study published today on ... Environmental Science & Technology . The study is scheduled to ... , The finding, by Rudolf Wu, Ph.D., and colleagues at ...
... Chemical Senses Center have succeeded in growing mature taste receptor ... been able to successfully keep the cells alive for a ... model opens a range of new opportunities to increase scientists' ... in nutrition, health and disease. , "We have an important ...
Cached Biology News:Rochester scientists develop fast-working biosensor 2Ocean 'dead zones' trigger sex changes in fish, posing extinction threat 2Living taste cells produced outside the body 2Living taste cells produced outside the body 3
(Date:7/1/2015)... BANGALORE, India , July 1, 2015 /PRNewswire/ ... uses next generation sequencing technology to empower cancer care, ... as chief executive officer. In his expanded role ... for all strategy, business expansion and worldwide operations effective ... as Strand,s chairman and CEO since its founding in ...
(Date:7/1/2015)... , July 1, 2015 InferMed ... technology will ... evidence-based clinical s olutions suite   ... and medical information products and services, announced today the acquisition ... decision support (CDS) technology company. InferMed,s Arezzo technology ...
(Date:6/30/2015)... ... 2015 , ... Students and faculty from Beijing City University ... “Integrative Biotechnology,” an applied biotechnology course team-taught by faculty members from both institutions. ... from both universities and is taught on both continents. , “Our alliance with ...
(Date:6/30/2015)... Americord Registry, one of the fastest growing cord blood banks ... at Kirkland & Ellis LLP, as the newest member of ...   "We are thrilled about Andrew Horne,s ... , CEO of Americord. "He brings a wealth of knowledge ... growth and vision." Andrew Horne is ...
Breaking Biology Technology:Strand Life Sciences Names Scott A. Storrer CEO as Company Continues Global Expansion with Focus on Precision Medicine Product 2Strand Life Sciences Names Scott A. Storrer CEO as Company Continues Global Expansion with Focus on Precision Medicine Product 3Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 2Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 3Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 4Rivier University and Beijing City University Academic and Cultural Exchanges Begin 2Americord Registry Announces Andrew Horne as Advisory Board Member 2
... the financial technology subsidiary of Milwaukee-based Marshall & Ilsley ... Brasfield Corp. The company will become a Metavante subsidiary ... , ,Brasfield provides core banking processing and customer service ... from Kirchman Corp., a Metavante company. Brasfield also provides ...
... trademark rights by failing to meet the technical filing ... the Trademark Trial and Appeal Board, as demonstrated by ... the case, In re Borlind Gesellschaft for kosmetische ... (TTAB) denied a request for an extension of time ...
... Wis. -- Despite being forced to idle in the ... Oshkosh Truck Corp. and several partners completed a 132-mile course ... computer-controlled vehicle technology. , , TerraMax , one of five ... 12 hours and 51 minutes, according to Oshkosh Truck ...
Cached Biology Technology:Ruling enforces international trademark electronic filing requirements 2Ruling enforces international trademark electronic filing requirements 3Oshkosh's TerraMax rolls across finish line 2Oshkosh's TerraMax rolls across finish line 3
Consists of 4 separate 100mM solutions (ATP,GTP,CTP and UTP pH 7.5) as sodium salts. 98% Pure by HPLC...
Collected from sexually mature, mixed sex, mixed breed cats. Physiochemical constituents are measured to ensure lot-to-lot consistency....
Tracker Datamatrix TRxD reads any 1D and 2D barcodes within 0.5 seconds....
Donor feline serum and plasma...
Biology Products: