Navigation Links
Tips from the Journals of the American Society for Microbiology
Date:11/19/2009

One of the main contributing factors to dental cavities is overpopulation of acid-producing bacteria in the oral cavity that causes localized destruction of compromised dental hard tissue. Due to the episodic nature of cavities, long-term benefits of periodic treatments administered during routine office visits are minimal. Other delivery systems developed to maintain drug concentrations, including bioadhesive tablets, patches, films, and gels, aren't very effective on the tooth surface and often cause irritation resulting in poor patient compliance. Emphasis on the need for therapeutic strategies that target the bacterial aspect of the disease and a delivery platform that would maintain the drug concentration on the tooth surface is warranted.

In the study tooth-binding micelles (molecular particles) were developed and encapsulated with farnesol, an antimicrobial recently found to be effective against the cavity causing bacterium Streptococcus mutans UA159. When tested on a model tooth surface the micelles were able to swiftly bind and gradually release the encapsulated farnesol. Additionally, biofilm inhibition studies of the farnesol-containing tooth-binding micelles demonstrated that they were able to inhibit S. mutans UA159 at much higher levels than untreated blank control micelles.

"A tooth-binding micelle delivery platform for the prevention and treatment of dental carries has been designed and prepared in this study," say the researchers. "It is anticipated that the tooth-binding micelles have the potential to be formulated into mouth rinses that may have the merits of simple application, cultural acceptance, and improved patient compliance."

(F. Chen, X.M. Liu, K.C. Rice, X. Li, F. Yu, R.A. Reinhardt, K.W. Bayles, D. Wang. 2009. Tooth-binding micelles for dental carries prevention. Antimicrobial Agents and Chemotherapy, 53. 11: 4898-4902.)


'/>"/>

Contact: Carrie Slijepcevic
cslijepcevic@asmusa.org
American Society for Microbiology
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Tips from the Journals of the American Society for Microbiology
2. ESA celebrates 100 years of insect science journals
3. Springer and the New York Botanical Garden Press join forces to publish botanical journals
4. 200 journals join in theme issues on poverty and human development
5. Tips from the Journals of the American Society for Microbiology
6. Humana Press journals now available on SpringerLink
7. Tips from the Journals of the American Society for Microbiology
8. Tips from the Journals of the American Society for Microbiology
9. Mycotoxin Research joins Springers life sciences journals program
10. Oxford Journals and the International Society for Computational Biology announce new partnership
11. Springer and Senckenberg society to collaborate on life sciences and geosciences journals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... Wildlife Conservation Society shows that no-take zones in ... such as lobster, conch, and fish recover from ... areas. , The reporttitled "Review of the Benefits ... literature from no-take areas around the world. The ... recognized expert in marine protected areas and fisheries ...
(Date:7/11/2014)... July 11, 2014--Researchers at the Department of Energy,s ... 100 awards, presented by R&D Magazine in recognition ... "These awards recognize the tremendous value of our ... "Research and development at the National Labs continues ... and pursue the scientific and technological innovations necessary ...
(Date:7/11/2014)... South Wales, Australia when NASA,s Aqua satellite passed overhead ... 11 (12:35 p.m. local time/11:35 p.m. EDT on July ... (NSW), the Moderate Resolution Imaging Spectroradiometer (MODIS) aboard captured ... smoke (light brown) from various fires. Actively burning areas, ... , The New South Wales, Australia Government website "NSW ...
Breaking Biology News(10 mins):Belize's lobster, conch, and fish populations rebuild in no-take zones 2ORNL wins eight R&D 100s 2ORNL wins eight R&D 100s 3ORNL wins eight R&D 100s 4
... Health has named researchers at Baylor College of Medicine ... and only recipients of the inaugural Quantum Grant for ... and blood vessels for the treatment of stroke. , ... Institute of Biomedical Imaging and Bioengineering (NIBIB), part of ...
... two candidate vaccines that may eventually be used together ... are published in the December 15 issue of The ... S. Graham, MD, PhD, and colleagues from the National ... the Fred Hutchinson Cancer Research Center in Seattle, and ...
... heart muscle ?even though it was grown in the ... the goal of creating replacement parts for damaged human ... just a spoonful of loose heart cells. , This ... in growing bioengineered heart muscle, or BEHM, with organized ...
Cached Biology News:First Quantum Grant to fund stem cell repair of damage from stroke 2Progress made in HIV vaccine development 2A new approach to growing heart muscle 2A new approach to growing heart muscle 3A new approach to growing heart muscle 4
(Date:7/13/2014)... (PRWEB) July 13, 2014 2014 Deep ... is a professional and in-depth study on the current ... China. , The report provides a basic overview of ... Global market analysis and Chinese domestic market analysis are ... competitive landscape of the market. A comparison between the ...
(Date:7/12/2014)... July 12, 2014 This ... reagents used in the life science industry. ... life science reagents market towards remarkable growth. ... and providers of life science reagents. , ... http://www.transparencymarketresearch.com/life-sciences-reagents-analytical-reagents.html . , The global life ...
(Date:7/11/2014)... 2014 /PRNewswire-iReach/ -- Maxim Peptide, a website that features ... solely in scientific experiments, is currently celebrating its second ... Maxim Peptide, which was created by the founders of ... updated website that now features a special deals section. ... with fascinating articles about peptide research, including a new ...
(Date:7/11/2014)... , Not for release, publication or ... any jurisdiction where to do so would constitute a violation ... plc ("Shire" or the "Company") (LSE: SHP, NASDAQ: ... it has held a meeting with representatives of AbbVie. ... prior agreement or approval of AbbVie. A further ...
Breaking Biology Technology:2014 Nano Silver Industry in Global and China Regions Development Proposals Analysis Available at DeepResearchReports.com 22014 Nano Silver Industry in Global and China Regions Development Proposals Analysis Available at DeepResearchReports.com 3Transparency Market Research: Life Science Reagents Market- PCR Reagent Kits, Cell and Tissue Culture, Flow Cytometry, Electrophoresis and Chromatography 2Transparency Market Research: Life Science Reagents Market- PCR Reagent Kits, Cell and Tissue Culture, Flow Cytometry, Electrophoresis and Chromatography 3Maxim Peptide Celebrates Second Anniversary Online with an Updated Website and Special Deals Section 2Shire plc - Statement re: Media Speculation 2
... Minds, Establishes New Company to Commercialize ... Novel Technology from UC ... investment,firm specializing in early stage university business ventures, has,established RF ... technology invented at UC Davis., The newly formed RF ...
... TAIAN CITY, Shandong, China, June 30 /Xinhua-PRNewswire-FirstCall/ --,China ... or "the,Company"), one of the leading plasma-based pharmaceutical ... announced that the Company,received the approval from the ... new plasma collection station in Pu Bei County, ...
... Cellumen, Inc., the Cellular,Systems Biology Company, announced today ... Center for Toxicology Research (NCTR), a,research center of ... Cellumen will use its proprietary CellCiphr(R) toxicity risk,assessment ... toxicity,compounds including both failed and marketed drugs for ...
Cached Biology Technology:Allied Minds Launches Novel Disinfectant/Disinfestant Technology Start-up With UC Davis 2China Biologic Products Announces Approval for Setting Up a New Plasma Collection Station in Pu Bei County, Guangxi Province 2China Biologic Products Announces Approval for Setting Up a New Plasma Collection Station in Pu Bei County, Guangxi Province 3Cellumen to Collaborate With the NCTR of the FDA to Apply Cellular Systems Biology (CSB(TM)) to Predictive Toxicology 2
3'-O-Methylguanosine 5'-Triphosphate, Sodium, 1 umol. Category: Nucleotides & Enzymes & Biochemicals, Nucleotides, Additional Nucleotide Products....
Porcine Serum Available Anticoagulants: N-02: Citrate N-04: Heparin (Na) N-06: K2EDTA N-08: Potassium Oxalate N-10: EDTA (Na) N-03: Alsevers N-05: ACD N-07: CPD N-09: K3EDTA N-11...
... Rat adult normal paraffin tissue ... genes or proteins of interest in ... tissues. Rat brain, heart, kidney, ... tissues are arrayed on positively charged ...
GENOMIPHI V2 DNA AMP KIT 25RXN, 1 EA. Category: Genomics DNA Amplification....
Biology Products: