Navigation Links
Tips from the American Journal of Pathology
Date:3/24/2009

Tracking Acute Kidney Injury

Dr. Eisei Noiri and colleagues at the University of Tokyo, Japan identified a novel biomarker to monitor acute kidney injury. They present their data in the April 2009 issue of The American Journal of Pathology.

Acute kidney injury may be reversible if treated promptly and appropriately. Novel biomarkers therefore need to be developed to identify injury at early time points as well as to estimate the severity of the damage.

Negishi et al examined whether levels of urinary L-type fatty acid-binding protein (L-FABP), a protein found in the kidney that is secreted in the urine upon kidney injury, could be used to monitor acute kidney injury. Levels of L-FABP correlated with the level of acute kidney injury at significantly earlier time points than levels of conventional renal markers such as blood urea nitrogen (BUN) or urinary N-acetyl-D-glucosaminidase (NAG). In addition, L-FABP showed better correlation than BUN or NAG with final histological injury scores, especially at early time points.

L-FABP thus represents a better choice than conventional renal markers for evaluating early acute kidney injury. Future studies will "evaluat[e] various human AKI populations to confirm the significance of urinary L-FABP as a forecasting biomarker of pathological and functional damage."

Negishi K, Noiri E, Doi K, Maeda R, Sugaya T, Portilla D, Fujita T : Monitoring of urinary L-type fatty acid binding protein predicts histological severity of acute kidney injury. Am J Pathol 2009, 174: 1154-1159


New Target for Alzheimer's Disease Therapy

Researchers at the VU University Medical Center, Amsterdam and the University of Amsterdam, The Netherlands discovered that the unfolded protein response contributes to nerve cell death in Alzheimer's Disease. This report can be found in the April 2009 issue of The American Journal of Pathology.'/>"/>

Contact: Angela Colmone
acolmone@asip.org
301-634-7953
American Journal of Pathology
Source:Eurekalert

Page: 1 2 3 4 5

Related biology news :

1. The American Association for Cancer Research congratulates Margaret Hamburg, M.D.
2. American Chemical Societys weekly PressPac -- March 11, 2009
3. American carnivores evolved to avoid each other, new study suggests
4. News from the March 2009 Journal of the American Dietetic Association
5. Many middle-aged and older Americans not getting adequate nutrition
6. American Institute of Physics announces awards for best science writing
7. Honest crabs, power to the hungry, nice mice and clever meerkats: News from the American Naturalist
8. Carnegies Doug Koshland elected Fellow of the American Academy of Microbiology
9. African-Americans aware and accepting, but often do not receive, the HPV vaccine
10. Statement by the Egg Nutrition Center and American Egg Board on Diabetes Care study on egg consumption
11. News from the February 2009 Journal of the American Dietetic Association
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... LAFAYETTE, Ind. - Regulated deer hunts in Indiana state ... from decades of damage caused by overabundant populations of ... team led by Michael Jenkins, associate professor of forest ... Resources policy of organizing hunts in state parks has ... and wildflowers rendered scarce by browsing deer. , ...
(Date:7/9/2014)... Sexual selection refers to species, selection for traits ... type of natural selection enhances opportunities to mate, the ... Biologists at the University of California, Riverside have now ... of a placenta are linked. Describing the life ... the family Poeciliidae, the researchers found that species with ...
(Date:7/9/2014)... NY, July 9, 2014Biofuels derived from the oils produced ... fossil fuels. To achieve this goal, optimization of cost ... open pond systems, is needed. Sapphire Energy has developed ... open pond algae cultivation systems, described in Industrial ... Inc., publishers. The article is available on the ...
Breaking Biology News(10 mins):Hunting gives deer-damaged forests in state parks a shot at recovery 2Biologists link sexual selection and placenta formation 2Biologists link sexual selection and placenta formation 3Biologists link sexual selection and placenta formation 4Controlling contamination in open algae ponds for biofuels 2
... Improperly applied fertilizer to newly placed sod may result ... is the best time to apply fertilizer and what kind ... those questions is a team of scientists from Texas A&M ... and water management; Dr. Ben Wherley, assistant professor of turfgrass ...
... creatures called rhabdopleurids reside on the ocean floor, building homes ... are small, and the critters are by no means the ... way -- and survived -- for more than 500 million ... species that also descended from a common ancestor, according to ...
... Researchers in Aalto University have developed a new concept ... information. This was enabled by the discovery that upon ... two water droplets rebound like billiard balls. In ... , the researchers experimentally determined the conditions for rebounding ...
Cached Biology News:Turf study to monitor runoff, establish fertilizer management practices 2Ancient, bottom-dwelling critter proves: Newer isn't always better 2Towards computing with water droplets -- superhydrophobic droplet logic 2
(Date:1/15/2014)... 2014 TaiGen Biotechnology Company, Limited ("TaiGen") today announced ... a leading Russian pharmaceutical company, to develop and commercialize ... Federation , Turkey and ... a novel antibiotic for the treatment of bacterial infections ...
(Date:1/14/2014)... 2014 Carahsoft and CDS Federal Services ... 2014 at 2pm EST (11am PST), “Natural Language Processing: ... on how technology can turn raw, heterogeneous data into ... agencies. The online webinar will last approximately one hour. ...
(Date:1/14/2014)...  3D Communications, a leading provider of strategic communications services to corporations ... in the United States and ... , JD, is returning to the firm,s Washington, D.C. ... after more than two years of service as Associate Commissioner for ...
(Date:1/14/2014)... 2014 EquitiesIQ, a leading informational research ... Alliqua is an emerging biomedical company acquiring, developing, manufacturing, ... market. , Free report download: http://equitiesiq.com/reports/alliqua/ , ... management team and Board, which launched the company’s new ...
Breaking Biology Technology:TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2Former FDA Associate Commissioner Returns To 3D Communications 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3
... $215 million , , Acquisition will ... , CARLSBAD, Calif. and ABBOTT PARK, Ill., ... and Abbott (NYSE: ABT ) announced today that Abbott ... Ibis Biosciences, Inc., an Isis subsidiary, for a closing purchase price ...
... Trusted LASIK Surgeons directory service and website at ... consumers seeking to improve their vision. What sets the ... process ensuring that only those who are among the ... in the United States are listed. Refractive eye surgeons, ...
... retina cells or other tissues can be tracked by ... record of movement and gene expression. The new technique, ... , will allow detailed analyses of correlations between behavior, ... team of researchers from the University of Southern California, ...
Cached Biology Technology:Abbott Exercises Its Option to Acquire Ibis Biosciences, a Subsidiary of Isis 2Abbott Exercises Its Option to Acquire Ibis Biosciences, a Subsidiary of Isis 3Abbott Exercises Its Option to Acquire Ibis Biosciences, a Subsidiary of Isis 4Abbott Exercises Its Option to Acquire Ibis Biosciences, a Subsidiary of Isis 5Hawaii LASIK Eye Surgery Expert Dr. John D. Olkowski Qualifies and Lists with Trusted LASIK Surgeons 2Hawaii LASIK Eye Surgery Expert Dr. John D. Olkowski Qualifies and Lists with Trusted LASIK Surgeons 3Hawaii LASIK Eye Surgery Expert Dr. John D. Olkowski Qualifies and Lists with Trusted LASIK Surgeons 4Hawaii LASIK Eye Surgery Expert Dr. John D. Olkowski Qualifies and Lists with Trusted LASIK Surgeons 5Hawaii LASIK Eye Surgery Expert Dr. John D. Olkowski Qualifies and Lists with Trusted LASIK Surgeons 6Hawaii LASIK Eye Surgery Expert Dr. John D. Olkowski Qualifies and Lists with Trusted LASIK Surgeons 7
No description available in Ensembl. Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
15(S)-HETE-d8 is used as an internal standard for the quantification of 15(S)-HETE by stable isotope dilution mass spectrometry....
5(S)-HETE-d8 is used as an internal standard for the quantification of 5(S)-HETE by stable isotope dilution mass spectrometry....
...
Biology Products: