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Tip sheet for journalists: Equol, soy, menopause and bone health research published in Journal of Nutrition
Date:7/8/2010

, also called pharmacokinetics, and their biological actions. The authors note that if the theory that health benefits of soy-based diets are greater in equol-producers can be substantiated in studies, then for those adults who are unable to produce S-equol due to a lack of equol-producing bacteria in the intestine or some other factors, one option is to eat equol in the form of a nutraceutical.

" Equol: Pharmacokinetics and Biological Actions," Kenneth D. R. Setchell, of Pathology and Laboratory Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center in Ohio, and Carlo Clerici of Clinica di Gastroenterologia ed Epatologia, at the Universita` degli Studi di Perugia University of Perugia in Italy

4. Equol Review by an Epidemiologist

Lampe reviews the very limited body of a subset of research about equol, which includes animal studies involving S-equol, a mix of S- and R-equol or their "parental" compound, daidzein, and human epidemiologic studies of soy intake and equol production.

"Emerging Research on Equol and Cancer," Johanna W. Lampe, of the Cancer Prevention Program, Division of Public Health Sciences at the Fred Hutchinson Cancer Research Center in Seattle

5. Equol and Bone in Women and Mice

Soybean isoflavones, including daidzein and genistein, can inhibit bone loss, depending on the dosage, according to a number of studies using animal model with osteoporosis, without causing notable effects on reproductive organs. Ishimi reports in this article data from a year-long study in postmenopausal Japanese women, in which 25 received a daily dose of daidzein and the isoflavone genistein , and 29 received a placebo. In the women in the isoflavone group who could produce S-equol, the percent change in bone loss at the total hip (a decrease of 0.46 percent) and at the hip intertrochanteric region (a decrease of 0.04 percent) was significantly lower (P< 0.05 for both) than that of the
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Contact: Stephen McCauley
smccauley@porternovelli.com
202-973-3615
Porter Novelli
Source:Eurekalert

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