Navigation Links
Tiny tool to control growing blood vessels opens new potential in tumor research
Date:2/20/2009

Researchers at Uppsala University have developed a new tool that makes it possible to study the signals in the body that control the generation of blood vessels. The researchers' findings, published in the new issue of Lab on a Chip, enable scientists to determine what signals in the body attract or repel blood vessels, knowledge that is extremely interesting in tumor research.

The new invention is a tiny cell cultivation chamber of silicon plastic in which researchers can cultivate blood-vessel-rich tissue and simultaneously create targeted signals that instruct the vessels to go in a certain direction. This is of great interest to the international research world.

Angiogenesis is the process in the body that forms new blood cells, a process that is vital for life but can also be fatal in the worst case. Angiogenesis is desirable, for instance, in connection with wound healing, when new tissue needs to be grown. Undesirable angiogenesis, on the other hand, often occurs in connection with tumor growth. Through the newly generated blood vessels in the vicinity of the tumor, tumor cells receive nourishment and oxygen, which creates the conditions for tumor growth. One way to limit tumor growth may therefore be to counteract the new formation of blood vessels in the tumor, thereby cutting off the supply of nourishment and oxygen to the diseased area.

The scientists Irmeli Berkefors and Johan Kreuger's research is geared toward understanding the signals that control both normal and pathological angiogenesis. To understand this, it is important to construct experimental model systems in which they can study how concentration gradients of various signal proteins affect the direction in which a vessel grows.

"Our new method enables us to recreate and study gradients that control how blood vessels grow in the body. This is something of a research breakthrough. Now we can systematically evaluate newly identified signal
'/>"/>

Contact: Johan Kreuger
johan.kreuger@imbim.uu.se
46-018-471-4366
Uppsala University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Forget the freezer: Research suggests novel way to control water behavior
2. Controlling cucumber beetles organically
3. Nanotubes tapestry controls its growth
4. Control of blood vessels a possible weapon against obesity
5. Vitamins C and E and beta carotene again fail to reduce cancer risk in randomized controlled trial
6. Organic plant waste proves effective weed control for citrus trees
7. Motor nerve targeting to limb muscles is controlled by ephrin proteins
8. New satellite data reveal impact of Olympic pollution controls
9. Brain enzyme may play key role in controlling appetite and weight gain
10. Fractional dose of scarce meningitis vaccine may be effective in outbreak control
11. New control knobs for stem cells identified
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Tiny tool to control growing blood vessels opens new potential in tumor research
(Date:9/16/2014)... (17 September, 2014)More than $100 trillion in cumulative ... annual carbon dioxide (CO2)a 40 percent reduction of ... if the world expands public transportation, walking and ... released by the University of California, Davis, and ... , Further, an estimated 1.4 million early ...
(Date:9/16/2014)... us that we inherit certain traits from our parents ... how these genes play out by taking certain drugs ... exactly what a team of researchers at the Boston ... research of epigenetics research. , Epigenetics regulates gene ... and histone proteins, which prevent permanent mutations or alterations ...
(Date:9/16/2014)... that spelled doom for the dinosaurs 66 million years ... a much greater extent than their deciduous peers, according ... are published in the journal PLOS Biology . ... of thousands of fossilized leaves of angiosperms ... to reconstruct the ecology of a diverse plant community ...
Breaking Biology News(10 mins):Global shift away from cars saves US$100 trillion, eliminates 1,700 MT of CO2 pollution 2Global shift away from cars saves US$100 trillion, eliminates 1,700 MT of CO2 pollution 3Global shift away from cars saves US$100 trillion, eliminates 1,700 MT of CO2 pollution 4Global shift away from cars saves US$100 trillion, eliminates 1,700 MT of CO2 pollution 5Epigenetic drugs: A hope to treat cancer resistance and reduce cancer relapse? 2Epigenetic drugs: A hope to treat cancer resistance and reduce cancer relapse? 3Meteorite that doomed dinosaurs remade forests 2Meteorite that doomed dinosaurs remade forests 3Meteorite that doomed dinosaurs remade forests 4
... Louis, MO, USA, February 1, 2009 A special ... Journal of the American Dietetic Association presents findings ... Study (SNDA-III), conducted by Mathematica Policy Research, Inc., as ... Sponsored by the Food and Nutrition Service of the ...
... leaders in tropical biology and conservation, William F. Laurance, ... and Thomas E. Lovejoy, research associate at the Institute ... Center for Science, Economics and the Environment, have won ... in Ecology and Conservation Biology, announced on 30 Jan. ...
... LA Huijing Xia, PhD, a postdoctoral research associate ... of Pharmacology at LSU Health Sciences Center New Orleans, ... a recently identified enzyme in the brain plays a ... pressure. The LSUHSC research team showed that Angiotensin-converting enzyme ...
Cached Biology News:Results of the third school nutrition dietary assessment study published 2Results of the third school nutrition dietary assessment study published 3Results of the third school nutrition dietary assessment study published 4Smithsonian scientists receive coveted BBVA Ecology and Conservation Award 2LSUSHC researchers find potential new target for hypertension treatment 2
(Date:9/17/2014)... VIENNA , Sept. 17, 2014 ... compelling, quantitative data from a study of the cost ... at the 50 th Annual Meeting of the ... a poster session today, Christian Frois , Ph.D., ... in a series of planned Intarcia-sponsored, retrospective studies to ...
(Date:9/17/2014)... SAN FRANCISCO, Calif. , Sept. 17, 2014 /PRNewswire/ ... ), a molecular diagnostics company pioneering the field of ... Hall to chief operating officer. Mr. Hall ... spearhead the company,s commercial entry into endocrinology. Since 2012, ... operations, as well as managed care and billing functions. ...
(Date:9/17/2014)... (PRWEB) September 17, 2014 Escape Alert, LLC ... pets which will alert owners if their pet has escaped ... from an implanted microchip in the pet’s body. This is ... for pets have been around for many years, they are ... not able to track a pet’s location or alert the owner ...
(Date:9/17/2014)... MA (PRWEB) September 17, 2014 ... Safety (ACRES) , a multi-stakeholder non-profit collaborative building ... efficiency in clinical research, today announced Phase 3 ... , Amir H. Kalali, Vice-President, ... and Arti Bajpai, President, Compliance and Quality Integration ...
Breaking Biology Technology:Intarcia Reveals New Insights At EASD Meeting Characterizing The Burden Of Poor Control And Non-Adherence To Anti-Diabetic Therapies 2Intarcia Reveals New Insights At EASD Meeting Characterizing The Burden Of Poor Control And Non-Adherence To Anti-Diabetic Therapies 3Intarcia Reveals New Insights At EASD Meeting Characterizing The Burden Of Poor Control And Non-Adherence To Anti-Diabetic Therapies 4Intarcia Reveals New Insights At EASD Meeting Characterizing The Burden Of Poor Control And Non-Adherence To Anti-Diabetic Therapies 5Veracyte, Inc. Announces Promotion of Christopher M. Hall To Chief Operating Officer 2Veracyte, Inc. Announces Promotion of Christopher M. Hall To Chief Operating Officer 3Veracyte, Inc. Announces Promotion of Christopher M. Hall To Chief Operating Officer 4Implantable Microchip for Pets with GPS Tracking - Patent Filed by Escape Alert, LLC. 2Implantable Microchip for Pets with GPS Tracking - Patent Filed by Escape Alert, LLC. 3Global Standards Initiative for Clinical Research Sites Advances 2Global Standards Initiative for Clinical Research Sites Advances 3Global Standards Initiative for Clinical Research Sites Advances 4
... 17 Initial public offerings for LinkedIn and Dunkin Donuts, takeovers of Mead Johnson Nutrition and Harley-Davidson, and a Cold Stone Creamery sale are among the 10 deals predicted by ... ... ... ...
... , March 17 Valeritas, Inc., a medical technology company committed to the development and commercialization of innovative drug delivery solutions, announced today that it has hired James ... ... ... ...
... ... Converting to 3D Imaging , ... Thornwood, N.Y. (PRWEB) March 17, 2010 -- Carl Zeiss, a leading provider ... recently announced two exciting online promotions. For a limited time, and only available online, ...
Cached Biology Technology:From Donuts To Hogs - Which Brand Icons Might Be In Play? 2From Donuts To Hogs - Which Brand Icons Might Be In Play? 3From Donuts To Hogs - Which Brand Icons Might Be In Play? 4From Donuts To Hogs - Which Brand Icons Might Be In Play? 5From Donuts To Hogs - Which Brand Icons Might Be In Play? 6From Donuts To Hogs - Which Brand Icons Might Be In Play? 7From Donuts To Hogs - Which Brand Icons Might Be In Play? 8Valeritas Announces Appointment of New CFO 2Valeritas Announces Appointment of New CFO 3Carl Zeiss Offers Online Promotions 2
... that it uses a deep-UV deuterium bulb, which ... with a shutter (controlled via a TTL signal ... DH-2000 Deuterium Tungsten Halogen Light Source combines ... light sources in a single optical path. The ...
One controller two vessel system suitable for early stage of fermentation, and small scale, Application : cultivation of microorganisms and human or animal cells...
... These handy dispensers save space and ... and other garb. They are the ... parts used in labs, processing and ... charges and the particles they attract. ...
... used to reveal two distinct antigens in ... a Zymed polymer double staining detection method ... same human cell or tissue sample with ... using two different primary antibodies from mouse ...
Biology Products: