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Tiny molecules protect from the dangers of sex
Date:11/14/2010

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Through deep sequencing of the small RNAi pieces which mediate the silencing in C. neoformans, the team also identified abundant small RNAs which map to repetitive transposable elements that could cause mutations if not silenced.

These small RNAs were absent in mutant strains (rdp1) that were studied. One group of transposable elements was greatly expressed during mating of rdp1 mutant strains and these fungi showed an increased transposition and mutation rate in the next generation, leading the researchers to conclude that the RNAi pathway squelches transposon activity during the sexual cycle.


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Contact: Mary Jane Gore
mary.gore@duke.edu
919-660-1309
Duke University Medical Center
Source:Eurekalert

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