Navigation Links
Tiny amounts of alcohol dramatically extend a worm's life, but why?
Date:1/20/2012

rke said. "The cholesterol did nothing. We found that not only does ethanol work at a 1-to-1,000 dilution, it works at a 1-to-20,000 dilution. That tiny bit shouldn't have made any difference, but it turns out it can be so beneficial."

How little ethanol is that?

"The concentrations correspond to a tablespoon of ethanol in a bathtub full of water or the alcohol in one beer diluted into a hundred gallons of water," Clarke said.

Why would such little ethanol have such an effect on longevity?

"We don't know all the answers," Clarke acknowledged. "It's possible there is a trivial explanation, but I don't think that's the case. We know that if we increase the ethanol concentration, they do not live longer. This extremely low level is the maximum that is beneficial for them."

The scientists found that when they raised the ethanol level by a factor of 80, it did not increase the life span of the worms.

The research raises, but does not answer, the question of whether tiny amounts of ethanol can be helpful for human health. Whether this mechanism has something in common with findings that moderate alcohol consumption in humans may have a cardiovascular health benefit is unknown, but Clarke said the possibilities are intriguing.

In follow-up research, Clarke's laboratory is trying to identify the mechanism that extends the worms' life span.

About half the genes in the worms have human counterparts, Clarke said, so if the researchers can identify a gene that extends the life of the worm, that may have implications for human aging.

"It is important for other scientists to know that such a low concentration of the widely used solvent ethanol can have such a big effect in C. elegans," said lead author Paola Castro, who conducted the research as an undergraduate in Clarke's laboratory before earning a bachelor's degree in biochemistry from UCLA in 2010 and joining the Ph.D. p
'/>"/>

Contact: Stuart Wolpert
swolpert@support.ucla.edu
310-206-0511
University of California - Los Angeles
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Why bats, rats and cats store different amounts of fat
2. Scalable amounts of liver and pancreas precursor cells created using new stem cell production method
3. New study links excessive amounts of vitamin D to onset of atrial fibrillation
4. UCLA researchers engineer E. coli to produce record-setting amounts of alternative fuel
5. Recipe for family mealtimes calls for 3 ingredients in the right amounts
6. Large amounts of nitrogen stored beneath selected agricultural areas
7. Scientists identify seamounts as significant, unexplored territory
8. Breakthrough reveals blood vessel cells are key to growing unlimited amounts of adult stem cells
9. Seamounts reach a pinnacle in upcoming issue of Oceanography
10. Moderate amounts of protein per meal found best for building muscle
11. Will large amounts of soil carbon be released if grasslands are converted to energy crops?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/15/2014)... from digestion to disease resistance. Despite the fact that ... the planet, more is known about belly-button bacteria than ... colleagues working on Panama,s Barro Colorado Island discovered that ... to more than 400 different kinds of bacteria. The ... 7,000 different kinds. , Bacteria in tropical forests may ...
(Date:9/15/2014)... 2014) The so-called central dogma of molecular ... provided a simplified explanation for how genetic information ... , In reality, of course, the process is ... nearly 60 years ago by Nobel Laureate Francis ... one, there are multiple types of RNA, three ...
(Date:9/15/2014)... study indicates that lowland tapir populations may continue to ... Researchers from the Office National de la Chasse ... San Diego Zoo Global reviewed data retrieved from camera ... four years and compared this data to current harvest ... on hunting tapirs in French Guiana," said Matthias Tobler, ...
Breaking Biology News(10 mins):Smithsonian scientists discover tropical tree microbiome in Panama 2Scientists discover RNA modifications in some unexpected places 2
... Ireland Cancer Center of University Hospitals Case Medical Center ... breast cancers express the MUC-1 target. This first-of-its-kind finding, ... has paved the way for an upcoming vaccine trial ... that could potentially prevent recurrence of this aggressive type ...
... from the effects of acid rain, as wet weather counteracts ... The research, by Professor Steve Ormerod and Dr Isabelle Durance ... year period around Llyn Brianne in mid-Wales. Their findings are ... of Applied Ecology . Carried out in 14 streams, ...
... PULLAUP, WA This Christmas season, think twice about ... Christmas tree. The good, old-fashioned methodkeeping your tree in ... to keep your tree green and healthy. Researchers have ... Christmas trees; in fact, in several cases the chemical ...
Cached Biology News:Ireland Cancer Center researcher finds most triple-negative breast cancers express muc-1 target 2Climate-change set-back for acidified rivers 2Flame retardants prove ineffective on fresh-cut Christmas trees 2
(Date:9/15/2014)... 15, 2014   Global Science & Technology, ... products and services for satellite and weather systems, ... Integrated Services (OASIS) from the General Services Administration ... to provide the government best-value solutions for complex ... category in Pool 4. The OASIS SB award ...
(Date:9/15/2014)... Things can go downhill fast when a patient has ... multiply in a patient,s blood -- often too fast ... the human spleen and developed by a team at ... transform the way doctors treat sepsis. , "Even ... in intensive care units at least 30 percent of ...
(Date:9/15/2014)... , Sept. 15, 2014  iVinci Health LLC, ... comprehensive Patient Revenue Management system, branded as VisitPay®, has ... also announced the launch of a new extension to ... provides an easy and convenient way for patients to ... balances owed by them and their families. ...
(Date:9/15/2014)... 15 septembre 2014 La deuxième édition ... (semaine internationale sur la sensibilisation au plasma) ... conjointe de la Plasma Protein Therapeutics Association ... , l,IPAW vise à : , ... la collecte du plasma-aphérèse , Reconnaître la ...
Breaking Biology Technology:Global Science & Technology, Inc. Awarded GSA OASIS Small Business Contract 2Global Science & Technology, Inc. Awarded GSA OASIS Small Business Contract 3Blood-cleansing biospleen device developed for sepsis therapy 2Blood-cleansing biospleen device developed for sepsis therapy 3Blood-cleansing biospleen device developed for sepsis therapy 4iVinci Health Raises $5M to Fuel National Expansion, Announces Launch of Personal Finance Portal for Healthcare 2iVinci Health Raises $5M to Fuel National Expansion, Announces Launch of Personal Finance Portal for Healthcare 3L' International Plasma Awareness Week célébrera les donneurs et braquera les projecteurs sur les maladies rares 2L' International Plasma Awareness Week célébrera les donneurs et braquera les projecteurs sur les maladies rares 3
... N.J., May 30, 2012  Today, leading events organizer ... to showcase the latest developments and opportunities across a ... by the same team as InformexUSA, North America,s leading ... chemistry, and managed in conjunction with the UBM team ...
... California Institute for Nursing & Health Care (CINHC) released ... pilot New Graduate Nurse Transition to Practice Programs (RN ... San Francisco, found that the programs are making a ... graduates and increasing their employment opportunities in hospitals and ...
... 2012 Sequenom, Inc. (NASDAQ: SQNM ), a ... the Company,s participation at the Jefferies 2012 Global Healthcare Conference ... 4-7, 2012. Harry F. Hixson, Jr., Ph.D., ... beginning at 11:00 a.m. ET, to provide an overview of ...
Cached Biology Technology:Informex Returns To India In 2012 2Informex Returns To India In 2012 3Study Shows Transition to Practice Programs Get Nurses Employed 2
... locus encodes two unrelated proteins both of ... the cell cycle in a p53-dependent manner. ... rapid degradation of mdm2 proteinrequired for mdm2 ... This interaction is mediated by the ...
human Exodus-2 Research Focus: cytokine/growth factor Storage Temperature: -20C Shipping Temperature: 4C...
...
Gel Loading Buffer contains a precipitant to ensure that the samples sink into the wells and a tracking dye to allow the user to follow the progress of electrophoresis....
Biology Products: