Navigation Links
Timely technology sees tiny transitions
Date:6/23/2010

Scientists can detect the movements of single molecules by using fluorescent tags or by pulling them in delicate force measurements, but only for a few minutes. A new technique by Rice University researchers will allow them to track single molecules without modifying them -- and it works over longer timescales.

In the current issue of Nanotechnology, a team led by Jason Hafner, an associate professor of physics and astronomy and of chemistry, has shown that the plasmonic properties of nanoparticles can "light up" molecular interactions at the single-molecule limit in ways that will be useful to scientists.

Hafner's method takes advantage of the ability of metal nanoparticles to focus light down to biomolecular scales through an effect called localized surface plasmon resonance (LSPR). The gold nanoparticles ultimately used in the experiment scatter light in visible wavelengths, which can be detected and spectrally analyzed in a microscope.

"The exact peak wavelength of the resonance is highly sensitive to small perturbations in the nearby dielectric environment," said graduate student Kathryn Mayer, the lead student on the experiment. "By tracking the peak with a spectrometer, we can detect molecular interactions near the surface of the nanoparticles."

Hafner first discussed their progress at a 2006 conference after a presentation on gold nanostars his lab had developed. "We had extremely preliminary data, and I said, 'Maybe we've got it.' I thought we were close," he recalled.

What took time was finding the right particle. "We started with nanorods, which don't scatter light well, at least not the small nanorods we produce in my lab. Then we tried nanostars and found they were very bright and sensitive, but each was a different shape and had a different peak wavelength."

The team settled on bipyramids, 140-nanometer-long, 10-sided gold particles that focus light at their sharp tips, creating a halo-
'/>"/>

Contact: David Ruth
druth@rice.edu
713-348-6327
Rice University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Gold Standard/Elsevier offers timely, reliable drug pricing data, including average wholesale price
2. Free Webinar to Focus on Commercializing University Technology
3. Conference to discuss sensing technology developments and opportunities
4. Michael Graetzel wins the Millennium Technology Prize
5. Success with cisgenics in forestry offers new tools for biotechnology
6. Massive resources now directed at sustainable animal waste technology
7. Field Museum technology project wins prestigious award
8. Cutting-edge vaccine research to be showcased at AAPS National Biotechnology Conference
9. Biotherapeutic Innovations on Display at AAPS National Biotechnology Conference
10. Space technology revolutionizes archaeology, understanding of Maya
11. New LLNL detection technology identifies bacteria, viruses, other organisms within 24 hours
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... Spanish National Cancer Research Centre (CNIO) have discovered that ... regulates cell division in stratified epitheliathose that form part ... oesophagus or the vaginain adult organisms. According to the ... Nature Communications , this factor could also play a ... epithelia of the oesophagus and skin. , The pluripotency ...
(Date:7/9/2014)... 9, 2014Biofuels derived from the oils produced by algae ... To achieve this goal, optimization of cost effective strategies ... systems, is needed. Sapphire Energy has developed an innovative ... algae cultivation systems, described in Industrial Biotechnology , ... The article is available on the Industrial Biotechnology ...
(Date:7/9/2014)... the prevalence of antibiotic-resistant illness, Case Western Reserve ... disabling disease: blocking bacteria,s access to iron in ... siderophore, a small molecule, captures iron from two ... as well as how the body launches a ... appear in a recent edition of The ...
Breaking Biology News(10 mins):CNIO scientists discover that pluripotency factor NANOG is also active in adult organisms 2Controlling contamination in open algae ponds for biofuels 2Bacteria hijack plentiful iron supply source to flourish 2
... by intestinal worms a condition that affects more than ... immune system is more versatile than has long been thought. ... exploration in the search for treatments against autoimmune diseases like ... tissues. The findings, reported by scientists who performed the ...
... Forest Service Southern Research Station (SRS) scientists and partners ... faster than expected in the southern Appalachians and rapidly ... and cooperators from the University of Georgia published the ... Ecosystems . "The study marks the ...
... has found that modern lifestyle habits may play a bigger ... A review of the scientific evidence over the ... good oral hygiene and health education, may override the effects ... online in a Supplement to the journal Obesity Reviews ...
Cached Biology News:A worm-and-mouse tale: B cells deserve more respect 2A worm-and-mouse tale: B cells deserve more respect 3Study finds hemlock trees dying rapidly, affecting forest carbon cycle 2
(Date:1/15/2014)... Toronto, ON (PRWEB) January 15, 2014 ... an experimental new therapy for the treatment of tinnitus. ... unique tinnitus frequency, and over a period of weeks to ... Notched Sound Therapy in two forms: Notched Music and Notched ...
(Date:1/14/2014)... CA (PRWEB) January 14, 2014 Histogen, ... the products of cells grown under simulated embryonic conditions, ... license agreement with Suneva Medical, Inc. for physician-dispensed aesthetic ... , This agreement is an amendment to ...
(Date:1/14/2014)... Texas , Jan. 14, 2014 The ... and research medicinal plants and therapeutic derivatives thereof ... health professionals, and researchers about the challenges of ... http://photos.prnewswire.com/prnh/20100430/DC95601LOGO ) The Society ...
(Date:1/14/2014)... , Jan. 14, 2014  RXi Pharmaceuticals Corporation (OTCQX: ... and commercializing innovative therapies addressing major unmet medical ... received the Notice of Allowance from the United ... self-delivering RNAi compounds (sd-rxRNA®), for the treatment of ...
Breaking Biology Technology:Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 2Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3
... Mich., May 3, 2011 Adeona Pharmaceuticals, Inc. (AMEX: ... for serious central nervous system diseases, announced today that ... Trimesta™ (oral estriol) drug candidate for multiple sclerosis (MS) ... the National Institutes of Health/National Institute of Neurological Disorders ...
... Inc. (NYSE: LDR ), a recognized global ... domestic provider of outsourced medical physics services, today reported financial ...   Fiscal 2011 Second Quarter Highlights ... contribution from Medical Physics segment and international growth. Gross ...
... Verenium Corporation (NASDAQ: VRNM ), a pioneer ... today announced that Jeff Black, Senior Vice President and Chief ... Bright Lights Conference.  The presentation is scheduled to begin at ... take place at the Le Parker Meridien Hotel in New ...
Cached Biology Technology:Adeona's Multiple Sclerosis Clinical Trial Receives $1,594,553 Grant 2Adeona's Multiple Sclerosis Clinical Trial Receives $1,594,553 Grant 3Adeona's Multiple Sclerosis Clinical Trial Receives $1,594,553 Grant 4Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 2Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 3Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 4Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 5Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 6Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 7Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 8Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 9Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 10Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 11Landauer, Inc. Reports Fiscal 2011 Second Quarter Results 12Verenium to Present at MDB Capital Group's Bright Lights Conference 2Verenium to Present at MDB Capital Group's Bright Lights Conference 3
... The mycobacteria in Complete Freund's adjuvant attract ... site which enhances the immuneresponse. For this ... for the initial injections; Incomplete Freund's adjuvant ... (preferably in saline) are typically mixed with ...
The ELISA Kit for Hepatitis B Surface Antigen (HBsAg) is an in vitro enzyme immunoassay for the detection of HBsAg in human serum or plasma....
2,4-Dinitrophenyl hapten is conjugated to Keyhole Limpet (KLH) protein through lysine....
Alexa Fluor 350/488/594 Filter Set (Semrock Brightline) *mounted* *Zeiss Axio AF...
Biology Products: