Navigation Links
Tilted acoustic tweezers separate cells gently
Date:8/25/2014

of rows and columns form in a checkerboard pattern. In this case, the team from Penn State, MIT and Carnegie Mellon University used simulation programs to determine the angle the sound sources should be tilted at to produce the best separation. They report their results today (Aug. 25) online in the Proceedings of the National Academies of Science.

By tilting the sound source so that it is not perpendicular, the researchers created better separation distance and could more efficiently sort cells.

The acoustic tweezers are made by manufacturing an interdigital transducer, which creates the sound, onto the piezoelectric chip surface. Standard photolithography creates microchannels in which the liquid containing the cells flow.

The researchers created the separator, which can run continuously. The device separated 9.9-micrometer particles from 7.3-micrometer particles so efficiently that 97 percent of the 7.3-micrometer particles went to the correct location. The device can also separate cancer cells from white blood cells with high efficiency and purity. It is simple and inexpensive to fabricate and does not need strict alignment to achieve this separation.

"The method we describe in this paper is a step forward in the detection and isolation of circulating tumor cells in the body," said Subra Suresh, one of the study's authors and president of Carnegie Mellon University. "It has the potential to offer a safe and effective new tool for cancer researchers, clinicians and patients."

The researchers see devices like this one separating cancer cells from other cells, bacteria from blood, white blood cells from red blood cells and malaria parasites from blood, to name a few uses.


'/>"/>

Contact: A'ndrea Elyse Messer
aem1@psu.edu
814-865-9481
Penn State
Source:Eurekalert  

Page: 1 2

Related biology news :

1. How nerve cells flexibly adapt to acoustic signals
2. Passive acoustic monitoring reveals clues to minke whale calling behavior and movements
3. Aspirin intake may stop growth of vestibular schwannomas/acoustic neuromas
4. Elsevier launches new open access journal: Photoacoustics
5. Acoustic monitoring of Atlantic cod reveals clues to spawning behavior
6. Acoustic tweezers capture tiny creatures with ultrasound
7. Optical nano-tweezers take over the control of nano-objects
8. Green photon beams more agile than optical tweezers
9. New optical tweezers trap specimens just a few nanometers across
10. Newly demonstrated capabilities of low-powered nanotweezers may benefit cellular-level studies
11. A single gene separates aggressive and non-aggressive lymphatic system cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Tilted acoustic tweezers separate cells gently
(Date:8/12/2015)... 2015  Synaptics Inc. (NASDAQ: SYNA ), ... announced that four of its fingerprint ID products, ... been named FIDO Certified™ by the Fast IDentity ... Synaptics, Natural ID™ fingerprint solutions are fully compliant ... standard and are interoperable among other products and ...
(Date:8/6/2015)... REDWOOD CITY, Calif. , Aug. 6, 2015 ... (D-Silicon Valley) will visit Crossmatch ™ to ... secure networks and protect data. Crossmatch is a ... solutions whose technologies and expertise are helping federal ... operational efficiency and security.   "The ...
(Date:8/5/2015)... , August 5, 2015 Transparency ... "Facial Recognition Market - Global Industry Analysis, Size, Share, ... market for facial recognition is forecast to reach US$ ... increased demand for surveillance systems by civil and government ... of crimes and terrorist activities across the globe that ...
Breaking Biology News(10 mins):Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 2Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 3Rep. Honda to Visit Crossmatch in Redwood City 2Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 2Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 3Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 4Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 5Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 6
... upset by a social snubbing? Your genetics, not your friends, ... opium-like painkillers, called opioids, relieve not only physical pain, but ... reviewed by Faculty of 1000 Biology member Markus Heilig shows ... receptor can determine the intensity of people,s responses to social ...
... low in Antarctic snowmelt that occurred during the 2008-09 austral ... two main climate drivers, ENSO (El Nio - Southern Oscillation) ... Tedesco, Assistant Professor of Earth & Atmospheric Sciences at The ... who is also on the doctoral faculty at the CUNY ...
... within minutes after waking up have much higher levels of ... than those who wait to smoke, regardless of the number ... appear to reflect the risk of lung cancer, our results ... especially at risk for lung cancer," said researcher Joshua E. ...
Cached Biology News:CCNY professor foresees rising Antarctic snowmelt 2Increased nicotine levels detected in those who light-up earlier 2
(Date:8/28/2015)... -- According to a new market research ... Thawing Equipment, Alarms), by Biospecimen (Human Tissue, Stem Cells, ... - Global Forecast to 2020", published by MarketsandMarkets, the ... Million by 2020 from USD 2,150.48 Million in 2015, ... 2020. Browse 74 Tables and 95 ...
(Date:8/28/2015)... ... August 28, 2015 , ... Since the initial launch of FireflySci Inc. (FFS) in early ... excellent customer service. Images such as the Fonz in a lab coat and Large ... to the humdrum spectroscopy field. , FireflySci is proud to be the only ...
(Date:8/27/2015)... The National Necrotizing Fasciitis Foundation ... by doctors at Vanderbilt University Hospital in ... and Dr. John Crew , director of the ... Center in Daly City, CA. ... pioneered by Dr. Crew, that had previously saved the ...
(Date:8/27/2015)... ... 27, 2015 , ... Inc. Magazine released its annual list of the 5,000 ... in growth for the three years through 2014. Being named to the Inc. 5000 ... in the country. , “We are thrilled to make the Inc. 5000 list ...
Breaking Biology Technology:Biopreservation Market Worth 3,731.03 Million USD by 2020 2Biopreservation Market Worth 3,731.03 Million USD by 2020 3Biopreservation Market Worth 3,731.03 Million USD by 2020 4Biopreservation Market Worth 3,731.03 Million USD by 2020 5Cuvette Manufacturer FireflySci Launches Back to School Deals with Complimentary Shipping On All Orders 2Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 2Patient's Life and Eyes Saved from Gruesome Flesh-Eating Infection Consuming Her Face 3iLab Solutions Named to 2015 Inc. 5000 List 2iLab Solutions Named to 2015 Inc. 5000 List 3
... Joseph Fox 1 , Joanne B. Connolly ... 1 Shimadzu Scientifi c Inc., Columbia, US; ... , Introduction , ... no separation) acquisitions for the analysis of complex peptide mixtures. These include (i) ...
... Introduction , ... serial,dilution of reagents or compounds. IC 50 assays,are commonly used to ... the serial dilution,of proteins, compounds, or other detection,agents. These processes can be ... , , ...
... Introduction , ... ODS-100V and TSKgel ODS-100Z, excellent chromatographic performance and , ... sample types. TSKgel ODS-100Z , and TSKgel ODS-100V ... with 100 angstrom pores; each material is derivatized with difunctional , ...
Cached Biology Technology:LC-MALDI and MALDI-MS/MS for the Analysis of Complex Peptide Mixtures 2LC-MALDI and MALDI-MS/MS for the Analysis of Complex Peptide Mixtures 3LC-MALDI and MALDI-MS/MS for the Analysis of Complex Peptide Mixtures 4Serial Dilution with the Bravo Liquid Handling Platform 2Serial Dilution with the Bravo Liquid Handling Platform 3Serial Dilution with the Bravo Liquid Handling Platform 4Serial Dilution with the Bravo Liquid Handling Platform 5Serial Dilution with the Bravo Liquid Handling Platform 6Serial Dilution with the Bravo Liquid Handling Platform 7Serial Dilution with the Bravo Liquid Handling Platform 8Unique Surface Treatment of Novel TSK-GEL ODS Columns Provide Separation of Aqueous and Fat Soluble Vitamins 2Unique Surface Treatment of Novel TSK-GEL ODS Columns Provide Separation of Aqueous and Fat Soluble Vitamins 3
... CYCLES. An assay kit designed to detect ... PARP is an enzyme implicated in DNA ... is cleaved by caspase-3. Cleavage of PARP ... kDa is a hallmark of apoptosis. Each ...
... The Digital Clamp One can operate as ... as a Conductance (Dynamic) Clamp in electrophysiology research ... good as conventional analog equipment. • ... by very recent advances in the capabilities of ...
... but comes with a shutter (controlled via a ... The DH-2000 Deuterium Tungsten Halogen ... and tungsten halogen light sources in a single ... powerful, stable output from 215-200 nm. In addition, ...
... expressed in g per ml and is determined ... 6.8, of a 1 mg per ml solution. ... to agglutinate a 2% suspension of human blood ... 25 C. Preparation Note: Affinity purified ...
Biology Products: