Navigation Links
Third generation map of human genetic variation published
Date:9/1/2010

An international consortium today published a third-generation map of human genetic variation, called the HapMap, which includes data from an additional seven global populations, increasing the total number to 11 populations. The improved resolution will help researchers interpret current genome studies aimed at finding common and rarer genetic variants associated with complex diseases.

Any two humans are more than 99 percent the same at the genetic level. But, the small fraction of genetic material that varies among people can help explain individual differences in susceptibility to disease, response to drugs or reaction to environmental factors. Variation in the human genome is organized into local neighborhoods called haplotypes, which usually are inherited as intact blocks of DNA sequence information. Consequently, researchers refer to the map of human genetic variation as a haplotype map, or HapMap.

"The generated HapMap provides an important foundation for studies aiming to find genetic variation related to human diseases. It is now routinely used by researchers as a valuable reference tool in our quest to use genomics for improving human health," said Eric D. Green, M.D., Ph.D., director of the National Human Genome Research Institute (NHGRI), a part of the National Institutes of Health, which provided major funding for the HapMap Project.

The most common genetic differences among people are SNPs, single-nucleotide polymorphisms. Each SNP reflects a specific position in the genome where the DNA spelling differs by one letter in different people. SNPs serve as landmarks across the genome. The initial version of the HapMap contained approximately 1 million SNPs, and the second-generation map brought that total to more than 3.1 million SNPs. Over the last few years, researchers conducting genome-wide association studies have relied on publicly available data from the HapMap to discover hundreds of common genetic variants ass
'/>"/>

Contact: Geoff Spencer
301-402-0911
NIH/National Human Genome Research Institute
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. BIO-key(R) Announces Additional $245,000 in Third Quarter Public Safety Orders
2. Communication Intelligence Corporation Reports Third Quarter 2008 Financial Results
3. Orchid Cellmark Reports Third Quarter 2008 Financial Results
4. Results of the third school nutrition dietary assessment study published
5. CWRU receives $5 million from Ohio Third Frontier Commission
6. Discovery to aid in future treatments of third-world parasites
7. Quest Diagnostics Reports Strong Performance in Third Quarter 2009
8. Aware, Inc. Reports Third Quarter 2009 Financial Results
9. Aware, Inc. Reports Third Quarter 2009 Financial Results
10. Quest Diagnostics Reports Strong Performance in Third Quarter 2009
11. SCM Microsystems Reports Third Quarter 2009 Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... researchers have identified a gene that could help scientists ... protein in the cell membrane of plants that senses ... conservation machinery accordingly. , "It,s similar to a ... at Duke. , The findings, which appear Aug. ... it easier to feed the world,s growing population in ...
(Date:8/27/2014)... requires nerve cells to rearrange existing patterns of activity ... patterns, a study of monkeys has found. The scientists ... electrical activity of brain cell networks. The study was ... "We looked into the brain and may have seen ... said Aaron Batista, Ph.D., an assistant professor at the ...
(Date:8/27/2014)... invasive grass species frequently found in forests has created ... on American toads, a new University of Georgia study ... to the U.S. in the early 1900s, is one ... to more than a dozen states in the past ... and in forests, it can survive in widely diverse ...
Breaking Biology News(10 mins):Water 'thermostat' could help engineer drought-resistant crops 2Scientists plug into a learning brain 2Scientists plug into a learning brain 3More wolf spiders feasting on American toads due to invasive grass, UGA study shows 2More wolf spiders feasting on American toads due to invasive grass, UGA study shows 3
... One fifth of the standard dose of a commonly ... the full dose. This new finding should allow scarce ... in Africa. In a study initiated by the ... research arm of Doctors Without Borders/Mdecins Sans Frontires), and ...
... Institute,s Linheng Li Lab has identified the precise location of ... today in the Advance Online Publication of Nature . ... Institute,s support facilities to develop a new technology ex ... the dynamic behavior of stem cells. This technology enabled the ...
... University,s School of Biomedical Engineering and Science,s Center for Injury ... 2008. The Office of the Deputy Chief of ... the award for research that could ultimately help save eyesight ... The center was selected from 57 applicants from around ...
Cached Biology News:Stowers Institute's Linheng Li Lab expands understanding of bone marrow stem cell niche 2New dummy design and development wins US Department of Defense award 2
(Date:8/27/2014)... 27, 2014 Budding Biomedical Scientists ... University School participated in the Scientific Enrichment ... University’s School of Medicine . , ... unparalleled professional experience in the sciences and brings ... faculty and students for both academic and career ...
(Date:8/26/2014)... , Aug. 26, 2014  NeuroSigma, Inc., a ... to develop bioelectronic technologies, today announced that it has ... U.S. Securities and Exchange Commission relating to a proposed ... of shares to be offered and the price range ... Jefferies LLC will act as the book-running ...
(Date:8/26/2014)... Aug. 26, 2014 An analysis by Replikins, ... all Mers CoV virus strains has revealed ... to 2012.  This conservation and sharing of specific Replikin ... CoV Blocker-Vaccine™ candidate, as it did for the H5N1 ... of which have been found to be effective (1,2). ...
(Date:8/26/2014)... engineers from Singapore has successfully piloted the world,s ... communications. , With the weight of payloads being ... lightweight, low power-consuming, wireless communication system to do ... been a challenge for system designers. , The ... Nanyang Technological University in Singapore launched VELOX-I, which ...
Breaking Biology Technology:Students at Cleveland's University School Conduct Biomedical Research at Case Western Reserve University’s School of Medicine 2ZigBee in the Sky 2
... /PRNewswire/ - Cytochroma today announced that it,has appointed ... Affairs and Quality Assurance. Dr. Engel brings to ... and quality assurance,and will be responsible for directing ... that the Company has appropriate quality,systems in place. ...
... VLP vaccines gains momentum with launch of a Phase ... IIa study of Seasonal Influenza Vaccine, ... ) announced today vaccination of healthy volunteers in a Phase,II ... The Phase IIa randomized, placebo controlled clinical trial will,evaluate the ...
... Sept. 16 Accuray,Incorporated (Nasdaq: ARAY ), a ... its president and chief executive officer, Euan S.,Thomson, Ph.D., ... Sciences,Conference in New York City, on Thursday, September 25, ... live webcast of the presentation will be available online ...
Cached Biology Technology:Cytochroma appoints Steven I. Engel as Vice President of Regulatory Affairs and Quality Assurance 2Novavax Commences Clinical Testing of its Seasonal Influenza VLP Vaccine Candidate 2Novavax Commences Clinical Testing of its Seasonal Influenza VLP Vaccine Candidate 3Novavax Commences Clinical Testing of its Seasonal Influenza VLP Vaccine Candidate 4Novavax Commences Clinical Testing of its Seasonal Influenza VLP Vaccine Candidate 5Accuray Incorporated's CEO to Speak at UBS Global Life Sciences Conference 2
...
... Digital Sight DS-U2 camera controller is the successor ... designed to interface any of the cameras in ... computer through a USB2.0 interface. The DS-U2 transmits ... cumbersome installation by equipping both hub and mass ...
This unique buffer provides a gentle method for removal of primary and secondary antibodies to allow several reprobings on the same membrane. Gentle buffer will not alter the antigen for subsequent i...
...
Biology Products: