Navigation Links
Think zinc: Molecular sensor could reveal zinc's role in diseases
Date:8/30/2009

gth, and altered the second protein to collect that light. When the proteins attached to zinc ions, the proteins became pushed apart and the transmission of light between them became weaker. The researchers used a fluorescence microscope to detect the wavelengths of light emitted by the proteins. This revealed zinc in the cell, with coloured patches visible where the proteins detected zinc.

The researchers used their new sensor to look for zinc in pancreatic cells, where insulin is packaged around zinc ions. Previous research had suggested that in people with type 2 diabetes, the gene that controls the packaging process is often defective, affecting the way insulin is stored. The researchers found a high concentration of zinc ions inside certain parts of the cells where insulin is found. They hope their new sensor could help scientists look more closely at this to find out exactly how zinc is involved in diabetes.

"We can now measure very accurately the concentration of zinc in cells and we can also look at where it is inside the cell, using our molecular measuring device. This sort of information will help us to see what is going on inside different tissues, for example in the brain in Alzheimer's disease, where we also suspect zinc may be involved. We hope this new sensor will help researchers learn more about zinc-related diseases and potentially identify new ways of treating them," added Professor Rutter.

The researchers would now like to develop their new sensor to look at zinc in a living mouse model, so they can observe the movement of zinc in different tissues, for example in diabetes.


'/>"/>

Contact: Lucy Goodchild
lucy.goodchild@imperial.ac.uk
44-207-594-6702
Imperial College London
Source:Eurekalert

Page: 1 2

Related biology news :

1. MSU discoveries upend traditional thinking about how plants make certain compounds
2. 100 reasons to change the way we think about genetics
3. After a few drinks, older adults more impaired than they think
4. Stress disrupts human thinking, but the brain can bounce back
5. Rethinking the genetic theory of inheritance
6. Diverse landscapes are better: Policymakers urged to think broadly about biofuel crops
7. Diverse landscapes are better: Policymakers urged to think broadly about biofuel crops
8. Carnegie Mellons Philip LeDuc participates in think tank forums
9. Wetlands expert: China should think outside the flooding box with Three Gorges Dam
10. New book rethinks the relationship between sulfur and crops
11. Thinking it through: Scientists call for policy to guide biofuels industry toward sustainability
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2014)... NEW YORK , Dec. 8, 2014 You,ve been here ... but can,t remember your password, site key or the answer to ... grade teacher? Today, Hoyos Labs , a ... finally put an end to the frustration that comes with usernames, ...
(Date:12/10/2014)... N.C. , Dec. 9, 2014  Wake Forest Baptist Medical ... for its School of Medicine. Funding for this $50 million ... will be publicly launched next summer. The ... series R.J. Reynolds Tobacco Company complex, adjacent to 525@vine in ...
(Date:12/10/2014)... Markets ( http://www.researchandmarkets.com/research/xclcvw/biometrics_market ) has announced the ... report to their offering. ... and smart cards for projects such as rural banking ... the major trends witnessed in the market. Besides the ...
Breaking Biology News(10 mins):The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 4Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2
... WI, NOVEMBER 17, 2008 Global land use patterns ... urban stormwater management. Traditional stormwater management focuses on ... generally does little to restore the hydrologic cycle ... with low permeability. The lack of infiltration opportunities ...
... Mellon University,s Robotics Institute have received a total of ... Agriculture (USDA) to build automated farming systems. One is ... but both are designed to improve fruit quality and ... autonomous robotic vehicles or at fixed sites within the ...
... team of researchers led by investigators at the Albert ... that certain commonly-prescribed medications may have the unintended consequence ... finding could alter the way doctors prescribe migraine medicines. ... Headache , the Einstein-led study of more than ...
Cached Biology News:Urban trees enhance water infiltration 2Carnegie Mellon developing automated systems to enable precision farming of apples, oranges 2Carnegie Mellon developing automated systems to enable precision farming of apples, oranges 3Overuse of narcotics and barbiturates may make migraine worse 2
(Date:1/22/2015)... 2015 Dr. Greg Leyer of UAS Labs ... Natural Supplements Pre-Conference seminar on probiotics in San Diego, CA. ... continuing education conference for health care professionals. This year’s pre-conference ... of probiotics in health. Dr. Leyer spoke about the emerging ...
(Date:1/22/2015)... 2015 Selexis SA, a serial innovation ... Banks (RCBs) used for drug discovery to commercial manufacturing, ... include Next-Generation Sequencing (NGS) data packages. The ... manufacturing by ensuring the integrity of the gene, validation ...
(Date:1/22/2015)... 22 de enero de 2015  El Dr. Paul ... llamada a nominaciones para 2015. Este prestigioso premio reconoce ... tiene el potencial para hacer, contribuciones destacadas para la ... hasta el 15 de marzo de 2015 a través ...
(Date:1/22/2015)... PALO ALTO, Calif. , Jan. 22. 2015  Varian Medical ... equipment and software, has been honored for its commitment to ... most sustainable companies. Varian is the highest ranked healthcare equipment ... ranking, announced today during the World Economic Forum at ...
Breaking Biology Technology:Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4Varian Honored Among World's 100 Most Sustainable Corporations 2
... April 3, 2008 Alba Therapeutics Corporation,today announced ... Chief Executive,Officer (CEO) and a member of its ... with SV Life Sciences Advisors, LLC. Previously, he ... the senior management team for several,successful entrepreneurial healthcare ...
... A policy comment in Science,today quotes Genelex out ... claims about the utility of CYP450,testing for particular ... testing is "required to effectively prescribe Paxil",( http://www.healthanddna.com/professional/paxil.html ... (paroxetine) is metabolized through CYP2D6. Pharmacogenetic,testing of this ...
... Term Development Agreement to Produce Reference Standard Reagents to ... ... 2008 Strategic,Diagnostics Inc. (Nasdaq: SDIX ) -- a ... sciences industry announced that it has,been selected by Science Applications ...
Cached Biology Technology:Alba Therapeutics Announces Appointment of Bruce A. Peacock as its Chief Executive Officer 2Science Fuels DNA Testing Controversy with Prejudicial Misquote 2Strategic Diagnostics Inc. Selected as Key Supplier to SAIC-F and the National Cancer Institute for the Development of a Comprehensive Portfolio of Antibodies for Use in Cancer Research 2Strategic Diagnostics Inc. Selected as Key Supplier to SAIC-F and the National Cancer Institute for the Development of a Comprehensive Portfolio of Antibodies for Use in Cancer Research 3