Navigation Links
The sweet mysteries of the nervous system
Date:5/10/2011

The antibody 5750 recognises a specific sugar residue on the cell surface, which is called LewisX. The research group lead by Prof. Dr. Andreas Faissner has now been able to use LewisX for the first time to separate different types of stem cells. The researchers report on their results in the Journal of Biological Chemistry.

Unexpected sugar diversity

Antibodies that recognise the LewisX sugar residue are used routinely to identify so-called neural stem cells from which the various cells of the nervous system originate. Prof. Faissner's team has now shown that the designation "LewisX" does not just cover a single sugar motif, but a whole range of different sugar residues. Different types of neural stem cells are equipped with individual combinations of LewisX sugar residues on their cell surface. The new Bochum antibody 5750 recognises a different LewisX sugar residue to the antibodies previously used. "This sugar diversity could also be interesting for cancer diagnosis" Prof. Faissner explained, "because LewisX sugars have also been detected on tumour cells".

Identifying properties of stem cells

With the aid of the new antibody 5750, certain types of neural stem cells can be isolated from a mixture of different cell types. The aim of Prof. Faissner's research group is now to examine the properties of the stem cells which carry the LewisX sugar residues. The researchers have already found out that the LewisX motif on the cell surface changes when the stem cells develop further for example into oligodendrocytes, which form the insulation layer of the nerve cells, or into nerve cells themselves.


'/>"/>

Contact: Dr. Andreas Faissner
andreas.faissner@rub.de
49-234-322-3851
Ruhr-University Bochum
Source:Eurekalert  

Page: 1

Related biology news :

1. TB bacterium uses its sugar coat to sweeten its chances of living in lungs
2. Johns Hopkins researchers detect sweet cacophony while listening to cellular cross-talk
3. Bumblebees learn the sweet smell of foraging success
4. Honey adds health benefits, is natural preservative and sweetener in salad dressings
5. Sweetened beverage consumption increases in the US
6. New standard for popular stevia-based sweetener to assure products quality
7. Spun-sugar fibers spawn sweet technique for nerve repair
8. Liking sweets makes sense for kids
9. Red pandas reveal an unexpected (artificial) sweet tooth
10. Quality and purity of popular stevia sweetener strengthened by new reference standards
11. The bitter side of sweeteners
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
The sweet mysteries of the nervous system 
(Date:8/4/2015)... (NASDAQ: AMRI ) today reported financial and operating results for ... , Second quarter contract revenue of $ 85.2 ... Adjusted contract margins of 26 % , ... in EPS from royalties in the current quarter , ... are very pleased to present another strong financial quarter, with all ...
(Date:7/31/2015)... , 31 de julio de 2015 ... (ICG-10,  www.icg-10.org ) del 22 al 25 de octubre ... La conferencia celebra su décimo aniversario este ... convertido en una de las reuniones anuales más influyentes ... es una de las conferencias científicas más dinámicas, entusiastas ...
(Date:7/31/2015)... La 10 th International Conference on Genomics ... 22 al 25 de octubre de 2015 en ... conferencia celebra su décimo aniversario. Desde su inauguración en el ... reuniones anuales más influyentes del mundo en el campo ,ómico, ... y mejores a nivel científico. ICG-10 se ...
Breaking Biology News(10 mins):AMRI Announces Second Quarter 2015 Results 2AMRI Announces Second Quarter 2015 Results 3AMRI Announces Second Quarter 2015 Results 4AMRI Announces Second Quarter 2015 Results 5AMRI Announces Second Quarter 2015 Results 6AMRI Announces Second Quarter 2015 Results 7AMRI Announces Second Quarter 2015 Results 8AMRI Announces Second Quarter 2015 Results 9AMRI Announces Second Quarter 2015 Results 10AMRI Announces Second Quarter 2015 Results 11AMRI Announces Second Quarter 2015 Results 12AMRI Announces Second Quarter 2015 Results 13AMRI Announces Second Quarter 2015 Results 14AMRI Announces Second Quarter 2015 Results 15AMRI Announces Second Quarter 2015 Results 16AMRI Announces Second Quarter 2015 Results 17AMRI Announces Second Quarter 2015 Results 18AMRI Announces Second Quarter 2015 Results 19AMRI Announces Second Quarter 2015 Results 20AMRI Announces Second Quarter 2015 Results 21AMRI Announces Second Quarter 2015 Results 22AMRI Announces Second Quarter 2015 Results 23AMRI Announces Second Quarter 2015 Results 24La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 3La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 2La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 3
... A fixable error in the way carbon is counted in ... undermine efforts to reduce greenhouse gas emissions by using biofuels, ... scientists. "The promise of biofuels made from biomass is ... Robertson, Michigan State University professor of crop and soil sciences ...
... the expansion of oxygen-deficient or oxygen minimum zones (OMZs), also ... carbon is captured and sequestered on the seafloor and alter ... ocean carbon sequestration. Despite the importance of these effects, very ... how they respond to environmental changes. In the Oct. ...
... bioethicist who specializes in moral dilemmas families face when making ... March of Dimes Distinguished Lectureship in Perinatal Bioethics. ... Lantos, MD, a nationally-recognized pediatrician and ethicist, delivered his lecture ... American Society of Bioethics and Humanities, 11th annual meeting here ...
Cached Biology News:Miscounting bioenergy benefits may increase greenhouse gas release 2Model microbial community for studying expanding dead zones characterized 2Model microbial community for studying expanding dead zones characterized 3March of Dimes establishes 2 new perinatal bioethics awards 2
(Date:8/26/2015)... San Bruno, CA. (PRWEB) , ... August 26, 2015 , ... ... three major conferences to develop new business relationships with local sponsors in southern California. ... services to facilitate their drug development processes and regulatory pathways., , ...
(Date:8/25/2015)... Aug. 25, 2015   WuXi PharmaTech (Cayman) Inc. ... and technology platform company serving the pharmaceutical, biotechnology, and ... Pharm," Hong Kong Exchange Stock Code: 0950), a research-based ... with 20 years of operations in ... have signed an agreement whereby WuXi,s Laboratory Testing Division ...
(Date:8/25/2015)... Menomonie, Wis. (PRWEB) , ... August 25, 2015 ... ... and fermentor at its research facility in Knapp, Wis. The company has added ... Biostat C15 Fermentor allows detailed data collection during bacterial or fungal fermentation process ...
(Date:8/25/2015)... ... 25, 2015 , ... One of the world’s foremost authorities on supply chain ... has been on a mission for the past two weeks. She’s been scrambling to ... from the two massive explosions that occurred on August 12 at the Ruihai International ...
Breaking Biology Technology:PRC Clinical To Attend Major Industry Conferences And Meet Sponsor Companies In The San Diego Biotech Hub 2PRC Clinical To Attend Major Industry Conferences And Meet Sponsor Companies In The San Diego Biotech Hub 3WuXi PharmaTech to Be Exclusive Supplier of Laboratory Testing Services to Lee's Pharm 2WuXi PharmaTech to Be Exclusive Supplier of Laboratory Testing Services to Lee's Pharm 3New centrifuge and fermentor expand product development capacity at Vets Plus 2Resilinc Supply Chain Expert Warns: Impact of Tianjin Chemical Explosions Will be Far Worse than Reported 2Resilinc Supply Chain Expert Warns: Impact of Tianjin Chemical Explosions Will be Far Worse than Reported 3Resilinc Supply Chain Expert Warns: Impact of Tianjin Chemical Explosions Will be Far Worse than Reported 4
... understood condition that, in the two years since its discovery, ... as many as half a million bats. Now researchers have ... save the affected bats: providing localized heat sources to the ... spreading so rapidly," says Justin Boyles, a graduate student in ...
... SANTA CLARA, Calif., March 5 Finesse Solutions, ... and control solutions for bioprocess applications, and Nova ... process monitoring announced the release of a TruBio(TM) ... and Nova FLEX(TM) analyzers. OPC is the de ...
... Announced Ergonomics Programs Prove Vital in a Slow Economy ... Annual National Ergonomics Conference and Exposition (NECE) will be held ... As of today, nearly a year prior, a remarkable ... including Sherry Rose, Ergonomics Product Manager for AliMed, are already ...
Cached Biology Technology:Ecologists propose first prevention for white-nose syndrome death in bats 2Ecologists propose first prevention for white-nose syndrome death in bats 3OPC Connectivity Between TruBio Software and Nova FLEX Analyzers 2National Ergonomics Conference and Expo Reaches 94% Exhibitor Renewal Rate 2
... PBL's bioassays for interferons are cytopathic effect ... assays. Sample types include; tissue culture supernatents; ... In these assays, one unit is defined as ... reduce the cytopathic effect of viral infection by ...
... PBL's bioassays for interferons are cytopathic effect ... assays. Sample types include; tissue culture supernatents; ... In these assays, one unit is defined as ... reduce the cytopathic effect of viral infection by ...
OmniSlide thermal Cycler for slide applications. 20 slide capacity. Humidity Chamber. Slide Rack can be transferred directly to Wash Module to avoid handling individual slides....
... The BioPrime Plus Array CGH Genomic Labeling ... enable reproducible labeling of genomic DNA samples ... in both indirect and direct labeling formats, ... Systems provide a flexible solution to your ...
Biology Products: