Navigation Links
The sound of melanoma can help doctors find cancer

COLUMBIA, Mo. Knowing the stage of a patient's melanoma is important when choosing the best course of treatment. When the cancer has progressed to the lymph nodes, a more aggressive treatment is needed. Examining an entire lymph node for cancer takes much effort and time; a new technique might help make the process more efficient. University of Missouri researchers in the Christopher S. Bond Life Sciences Center are studying how photoacoustics, or a laser-induced ultrasound, could help scientists locate the general area of the lymph node where melanoma cells could be residing. This new technology could help doctors identify the stage of melanoma with more accuracy.

"This method can be used to determine if the cancer has spread from stage 2, where the melanoma is still just in the skin lesion, to stage 3, where the melanoma has spread to the lymph nodes," said John Viator, assistant professor in the Department of Biological Engineering and Department of Dermatology . "If the cancer is still at stage 2, a simple procedure can remove that lesion. If the cancer has progressed from the initial skin lesion into the lymphatic region and possibly the bloodstream, doctors have to make serious decisions about patient care. The cancer may have possibly spread to other organs, such as the liver, lungs or brain."

Currently, pathologists must perform several specific and detailed tests to determine if there is cancer in the lymph nodes. This new technology could make the search less time-consuming by identifying a general area of the lymph node that might contain cancer.

"It's very similar to identifying a prize inside a cake," Viator said. "Instead of looking through the entire cake, we can use our ultrasound to pinpoint a slice or two that might contain the 'prize.' In the case of the lymph nodes, when you get a signal, this alerts the pathologist that this is an area of the node that might contain cancer cells. At that point, a pathologist would be able to narrow down the search, saving time and money."

In the photoacoustic method, a tabletop device scans a lymph node biopsy with laser pulses. About 95 percent of melanoma cells contain melanin, the pigment that gives skin its color, so they react to the laser's beam, absorbing the light. The laser causes the cells to heat and cool rapidly, which makes them expand and contract. This produces a popping noise that special sensors can detect. This method would examine the entire biopsy and identify the general area of the node that has cancer, giving pathologists a better idea of where to look for the cancer.

"This method is quicker and simpler and could be used to improve the efficiency of how doctors determine if the cancer has spread from the original skin lesion into the lymphatic system," Viator said. "This technology could be an important tool in our fight against cancer."

In the study, Viator took human cancer cells and placed them inside canine lymph nodes. Then, using the laser, he determined the best ways to locate the cancer cells. The next step is to try the procedure using human lymph nodes.


Contact: Kelsey Jackson
University of Missouri-Columbia

Related biology news :

1. Seeing the brain hear reveals surprises about how sound is processed
2. Bubble physicist counts bubbles in the ocean to answer questions about climate, sound, light
3. Ecologists sound out new solution for monitoring cryptic species
4. National Science Foundation Fellow uses ultrasound to research bog turtles
5. The sound of light: Innovative technology shatters the barriers of modern light microscopy
6. Laughing hyenas, wailing levees, the sound of cheese and blaring bagpipes
7. Ultrasound imaging now possible with a smartphone
8. Study compares sound from exploding volcanoes with jet engines
9. Sea Grant awards $820,000 for research under EPAs Long Island Sound study
10. Musicians have biological advantage in identifying emotion in sound
11. Timetable for Puget Sound restoration suffers setback
Post Your Comments:
Related Image:
The sound of melanoma can help doctors find cancer
(Date:11/26/2015)... 26, 2015 Research and Markets ( ... Fingerprint Sensors - Technology and Patent Infringement Risk Analysis" ... --> --> Fingerprint sensors using capacitive ... The fingerprint sensor vendor Idex forecasts an increase of ... mobile devices and of the fingerprint sensor market between ...
(Date:11/20/2015)... November 20, 2015 NXTD ) ... on the growing mobile commerce market and creator of ... Pereira , was recently interviewed on The RedChip ... on this weekend on Bloomberg Europe , Bloomberg ... --> NXTD ) ("NXT-ID" or the "Company"), ...
(Date:11/19/2015)...  Based on its in-depth analysis of the biometric ... the 2015 Global Frost & Sullivan Award for Product ... this award to the company that has developed the ... the market it serves. The award recognizes the extent ... customer base demands, the overall impact it has in ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... CITY , Nov. 25, 2015 /PRNewswire/ - Aeterna ... affirms that its business and prospects remain fundamentally ... , Zoptrex™ (zoptarelin doxorubicin) recently received DSMB recommendation ... to completion following review of the final interim ... Phase 2 Primary Endpoint in men with heavily ...
(Date:11/25/2015)... SAN DIEGO , Nov. 25, 2015 ... that management will participate in a fireside chat discussion ... New York . The discussion is ... Time. .  A replay will ... Contact:  Media Contact:McDavid Stilwell  , Julie NormartVP, Corporate ...
(Date:11/25/2015)... ... November 25, 2015 , ... Jessica Richman and ... early in their initial angel funding process. Now, they are paying it forward ... make early stage investments in the microbiome space. In this, they join ...
(Date:11/24/2015)... ... 2015 , ... The United States Golf Association (USGA) today announced Dr. Bruce ... Presented annually since 1961, the USGA Green Section Award recognizes an individual’s distinguished service ... , Clarke, of Iselin, N.J., is an extension specialist of turfgrass pathology in the ...
Breaking Biology Technology: