Navigation Links
The smell of danger
Date:6/28/2011

e able to detect?

In Liberles's lab at Harvard Medical School, graduate student David Ferrero began a search for other natural compounds that were detected by the TAARs. Working with commercially available predator and prey urine (used by gardeners to keep pests out of their crops and by hunters to mask their own scent or as lures for prey), Ferrero discovered that one of the 14 TAARs, TAAR4, detected the odor of several carnivores.

It seemed they had found a kairomone, a chemical that works like a pheromone, except that it communicates between members of different species instead of members of the same species. Prior to this discovery, the only known rodent-carnivore kairomones were a volatile compound produced by foxes, but not in that of other predators, and two non-volatile compounds produced by cats and rats (which prey on mice). Volatile compounds aerosolize and can be smelled at great distances; non-volatile compounds need to be sniffed more directly, something that would not be helpful in avoiding a predator directly but rather their terrain.

"One of the things that's really new here is that this is a generalized predator kairomone that's volatile," said Ferrero.

For rodents, it's the smell of danger.

Ferrero identified the compound that activates TAAR4 as 2-phenylethylamine, a product of protein metabolism. He then obtained specimens from 38 species of mammals and found elevated levels of 2-phenylethylamineby 18 of 19 species of carnivores, but not by non-carnivores (including rabbits, deer, primates, and a giraffe).

"It's been known so long that predator odors are great rodent deterrents, but we've discovered one molecule that's a key part of this ecological relationship," Ferrero said.

In a series of behavior tests, rats and mice showed a clear, innate avoidance to the smell of 2-phenylethylamine. The behavioral studies were repeated using a carnivore samples that had been depleted of 2-pheny
'/>"/>

Contact: David Cameron
david_cameron@hms.harvard.edu
617-432-0441
Harvard Medical School
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Clubbers can smell a good nightspot
2. Smell and taste experts at international conference -- April 13-17, 2011
3. Researchers unlock new secret to how smells are detected
4. The brain knows what the nose smells, but how? Stanford researchers trace the answer
5. Study shows pregnant mothers diet impacts infants sense of smell
6. Mice that smell light could help us better understand olfaction
7. New findings on taste and smell
8. Could smell play a role in the origin of new bird species?
9. Smelling the scenery in stereo
10. Monell Center joins with CAS to host Beijing meeting on taste and smell research
11. How the 100th protein structure solved at Diamond impacts our understanding of how insects smell
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/1/2015)... , April 1, 2015   Medisafe ™, ... million users across iOS and Android ... begun integrating biofeedback into the platform to allow patients ... outcomes. For the first time, patients will be able ... a dose impacts important biometrics, such as glucose levels ...
(Date:3/26/2015)... March 26, 2015 The Granite ... recreation and athletic club, today announced it has implemented ... freedom of movement for members and staff, while restricting ... comprehensive process, we selected FST,s IMID Access system because ... for our members and staff, in addition to unparalleled ...
(Date:3/24/2015)... , March 24, 2015   Crossmatch ™, ... today announced that its U.are.U ® 4500 ... Goorin Bros . to achieve PCI compliance ... secures access to the POS terminal, protecting the ... of data breaches. With one-third ...
Breaking Biology News(10 mins):Medisafe Announces Launch of Biometric Integration, Enabling Patients to Stay Adherent to Their Meds and See Tangible Health Results 2Granite Club First Private Club in North America to Implement FST Biometrics Secure Access Solution, as Part of Multi-million Dollar Expansion 2Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2
... Pixelplus Co.,Ltd. (Nasdaq: PXPL ), a ... and markets CMOS image sensors for various ... the "PM1002", the Company,s,new ,System-On-A-Chip, ("SoC") processor ... integrates a 32-bit RISC microprocessor and on-chip ...
... pinkish-purple ornamental flower, just patented by Cornell, can last for ... garden, it blooms all summer long in the cooler, northern ... new hybrid of the Inca lily ( Alstroemeria ), which ... that is set apart by its lavender-lilac flower color (which ...
... Sciences (SBS) WHAT: Latest Findings and Research on ... April 6-10, 2008 WHERE: SBS 14th Annual ... More than 2,500 researchers and professionals in the ... attend the 14th Annual Conference & Exhibition of the Society ...
Cached Biology News:Pixelplus Unveils Its PM1002 as A Practical Biometric Solution for Iris, Facial and Fingerprint Recognition 2Pixelplus Unveils Its PM1002 as A Practical Biometric Solution for Iris, Facial and Fingerprint Recognition 3Cornell patents a pink lily look-alike that blooms all summer long 2
(Date:4/23/2015)... MN (PRWEB) April 24, 2015 Ralco ... with Advanced Birthright Nutrition® (ABN) for the exclusive worldwide ... Cup. The new technology is a new in-line milk ... producers by allowing them to move supplementation milk cups ... , “This technology lets producers get Birthright™ ...
(Date:4/23/2015)... (PRWEB) April 23, 2015 The ... intends to conduct a groundbreaking pilot study to ... be reversed in as little as three to ... of metabolic and nutritional medicine—will aggressively target and ... and destroy our aging brain. These include oxidative ...
(Date:4/23/2015)... -- BioTE Medical President and Founder Gary Donovitz ... - Avoiding Over-Medication through Natural Hormone Balance" (ISBN: 9780990706458) ... at JW Marriott / Ritz Carlton Grande Lakes April ... Happier, is a welcomed response to many men and ... higher quality of life thanks to bio-identical hormone replacement ...
(Date:4/23/2015)...  Neurocrine Biosciences, Inc. (Nasdaq: NBIX ) announced ... 2015 results before the Nasdaq market opens on Thursday, ... call and webcast to discuss its financial results and ... at 8:00 a.m. Eastern Time (5:00 a.m. Pacific Time). ... by dialing 866-952-1906 (US) or 785-424-1825 (International) using the ...
Breaking Biology Technology:Ralco Acquires License to Birthright™ Moveable Milk Cup 2New Study Looks to Reverse Alzheimer’s Disease 2New Study Looks to Reverse Alzheimer’s Disease 3Release and Book Signing of BioTE Medical President Gary Donovitz M.D. 'Age Healthier Live Happier' at Age Management Medicine Group (AMMG) Conference 2Release and Book Signing of BioTE Medical President Gary Donovitz M.D. 'Age Healthier Live Happier' at Age Management Medicine Group (AMMG) Conference 3Neurocrine Biosciences Announces Conference Call and Webcast to Report First Quarter 2015 Results 2
... Bristol-Myers Squibb,Company (NYSE: BMY ) invites investors ... its annual meeting with stockholders at 10 a.m. ET ... and board items to be,transacted, senior executives will review ... how to listen to the webcast, please visit the,Investor ...
... CHAPEL HILL, N.C., April 30 Intense global ... force behind companies,adopting Strategic Alliances as the strategy ... a win-win situation for it to be sustainable ... alliance? Best Practices, LLC,s study on Forging,Partnerships That ...
... SAN DIEGO, April 30 SpectraScience, Inc. (OTC,Bulletin Board: ... that it has sold one of its WavSTAT(R) Optical ... The device will be used at,the University of Prague ... cancer., Generally, doctors search for polyps, which are ...
Cached Biology Technology:Biopharmaceutical Alliances: Forging Partnerships That Work 2Sale of Colon Cancer Diagnostic Tool to Czech Republic 2
Mouse monoclonal to OCIL ( Abpromise for all tested applications)....
Oxidative Stress-Inducible Protein Tyrosine Phosphatase...
... GenBank Accession Number : ... (C-QSQENQDTRPKVKAKK), corresponding to amino acids ... Formulation: antiserum in 0.05% sodium ... Assurance: routinely evaluated by immunoblot ...
Antibody specific for histone H3 acetylated at any of the five N-terminal lysine residues. Rabbit polyclonal serum. Antigen: Synthetic peptide derived from histone H3 N-terminal region, mulitpliy...
Biology Products: