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The shape of things to come: NIST probes the promise of nanomanufacturing using DNA origami
Date:3/7/2012

100-nanometer origami rectangle, takes up to 24 hours to self-assemble with an error rate of about 5 percent.

Other patterns that placed three and four dots in a line through the middle of the origami template were increasingly error prone. Sheathing the dots in biomaterials, a necessity for attaching them to the template, increases their effective diameter. A wider effective diameter (about 20 nanometers) limits how closely the dots can be positioned and also increases their tendency to interfere with one another during self-assembly, leading to higher error rates and lower bonding strength. This trend was especially pronounced for the four-dot patterns.

"Overall, we think that this process is good for building structures for biological applications like sensors and drug delivery, but it might be a bit of a stretch when applied to semiconductor device manufacturingthe distances can't be made small enough and the error rate is just too high," says Liddle.


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Contact: Mark Esser
mark.esser@nist.gov
301-975-8735
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

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The shape of things to come: NIST probes the promise of nanomanufacturing using DNA origami
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