Navigation Links
The shape of things to come: NIST probes the promise of nanomanufacturing using DNA origami
Date:3/7/2012

In recent years, scientists have begun to harness DNA's powerful molecular machinery to build artificial structures at the nanoscale using the natural ability of pairs of DNA molecules to assemble into complex structures. Such "DNA origami," first developed at the California Institute of Technology,* could provide a means of assembling complex nanostructures such as semiconductor devices, sensors and drug delivery systems, from the bottom up.

While most researchers in the field are working to demonstrate what's possible, scientists at the National Institute of Standards and Technology (NIST) are seeking to determine what's practical.**

According to NIST researcher Alex Liddle, it's a lot like building with LEGOssome patterns enable the blocks to fit together snugly and stick together strongly and some don't.

"If the technology is actually going to be useful, you have to figure out how well it works," says Liddle. "We have determined what a number of the critical factors are for the specific case of assembling nanostructures using a DNA-origami template and have shown how proper design of the desired nanostructures is essential to achieving good yield, moving, we hope, the technology a step forward."

In DNA origami, researchers lay down a long thread of DNA and attach "staples" comprised of complementary strands that bind to make the DNA fold up into various shapes, including rectangles, squares and triangles. The shapes serve as a template onto which nanoscale objects such as nanoparticles and quantum dots can be attached using strings of linker molecules.

The NIST researchers measured how quickly nanoscale structures can be assembled using this technique, how precise the assembly process is, how closely they can be spaced, and the strength of the bonds between the nanoparticles and the DNA origami template.

What they found is that a simple structure, four quantum dots at the corners of a 70-nanometer by
'/>"/>

Contact: Mark Esser
mark.esser@nist.gov
301-975-8735
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Shape, fit of reproductive organs evolve quickly and in concert, leaving size behind
2. Researchers find best routes to self-assembling 3-D shapes
3. Dramatic diversity of columbine flowers explained by a simple change in cell shape
4. Bats show ability to change their ear shapes, making their hearing more flexible
5. Crater shapes explained, how carnivorous plants bite, and doubts about faster-than-light neutrinos
6. Long bone shape: A family affair
7. Shape memory materials ready for mass production
8. Scripps Research scientists pinpoint shape-shifting mechanism critical to protein signaling
9. Research offers new way to target shape-shifting proteins
10. UBC researchers discover key mechanism that regulates shape and growth of plants
11. What shapes a bone?
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
The shape of things to come: NIST probes the promise of nanomanufacturing using DNA origami
(Date:7/31/2015)... China , 31 de julio de 2015 ... www.icg-10.org ) se celebrará por medio de BGI del 22 al ... . Este año, la conferencia celebra ... ICG se ha convertido en una de las reuniones anuales ... ser una de las reuniones más dinámicas, entusiastas y mejores ...
(Date:7/30/2015)... MOUNTAIN VIEW, Calif. , July 30, 2015 ... products and services for gene function analysis and ... CRISPR Guide RNA (sgRNA) Knockout Library targeting all ... to specifically and permanently "knock out" a gene,s ... library provides a high throughput screening tool so ...
(Date:7/23/2015)... , July 23, 2015 Research and ... of the "Global Outlook of the Biometrics ... The global biometrics market is ... and commercial applications owing to the uptake of ... a transformation that enhances the growth of biometrics ...
Breaking Biology News(10 mins):La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 2La 10th International Conference on Genomics (ICG-10) se llevará a cabo en octubre 3CELLECTA, INC. Announces Launch of Human Whole Genome CRISPR Knockout Library 2Global Outlook of the Biometrics Industry 2015 2Global Outlook of the Biometrics Industry 2015 3
... a fatal genetic disorder called Krabbe Disease can be saved ... from umbilical cord blood before symptoms of the disease develop, ... issue of the New England Journal of Medicine. , Without ... to lose all cognitive and motor functions and die by ...
... new 250 million year-old species of large, meat-eating ... from McGill University. Their findings published in today's ... amphibious carnivores from the Republic of Niger in ... carnivores in this area," says McGill paleontologist, and ...
... the hair at the back of the man's head gets ... lesser hair loss. There are hardly any successful counter-measures ?despite ... has long been suspected that hereditary factors are important in ... which genes are involved. The researchers in the team headed ...
Cached Biology News:Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells 2Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells 3Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells 4Tendency to hair loss inherited from the mother 2
(Date:7/29/2015)... SYDNEY , July 29, 2015 US-Australian ... NVGN ) today confirmed it is committed to progressing ... as soon as practicable and to ensure the Company ... Chief Executive Officer, Iain Ross , said the ... including the lead pre-clinical programs, discovery programs and academic ...
(Date:7/29/2015)... BIRMINGHAM, Ala., July 29, 2015 /PRNewswire/ ... the nation,s largest providers of post-acute healthcare services, ... reported its results of operations for the second ... second quarter was characterized by strong volume growth ... our Adjusted EBITDA," said Jay Grinney, President and ...
(Date:7/29/2015)... , July 29, 2015 ... has announced the addition of the "Global ... their offering. The Global Biosimilars Market, ... of the rapidly growing biosimilars market. With the ... striving to minimize costs, biosimilars are being viewed ...
(Date:7/29/2015)... 29, 2015  Therapath Neuropathology ( www.Therapath.com ), ... with VA and Military Medical centers both domestically ... (ENFD) and Sweat Gland Nerve Fiber Density (SGNFD) ... https://therapath.com/skin ). Demonstration of a ... on punch skin biopsy is a highly sensitive ...
Breaking Biology Technology:Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 2Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 3Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 4Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 5Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 6Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 7Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 8Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 9Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 10HealthSouth Reports Results for Second Quarter 2015 2HealthSouth Reports Results for Second Quarter 2015 3HealthSouth Reports Results for Second Quarter 2015 4HealthSouth Reports Results for Second Quarter 2015 5HealthSouth Reports Results for Second Quarter 2015 6HealthSouth Reports Results for Second Quarter 2015 7HealthSouth Reports Results for Second Quarter 2015 8HealthSouth Reports Results for Second Quarter 2015 9HealthSouth Reports Results for Second Quarter 2015 10HealthSouth Reports Results for Second Quarter 2015 11HealthSouth Reports Results for Second Quarter 2015 12HealthSouth Reports Results for Second Quarter 2015 13HealthSouth Reports Results for Second Quarter 2015 14HealthSouth Reports Results for Second Quarter 2015 15HealthSouth Reports Results for Second Quarter 2015 16HealthSouth Reports Results for Second Quarter 2015 17HealthSouth Reports Results for Second Quarter 2015 18HealthSouth Reports Results for Second Quarter 2015 19HealthSouth Reports Results for Second Quarter 2015 20HealthSouth Reports Results for Second Quarter 2015 21HealthSouth Reports Results for Second Quarter 2015 22HealthSouth Reports Results for Second Quarter 2015 23HealthSouth Reports Results for Second Quarter 2015 24HealthSouth Reports Results for Second Quarter 2015 25HealthSouth Reports Results for Second Quarter 2015 26HealthSouth Reports Results for Second Quarter 2015 27
... Cepheid (NASDAQ: CPHD ) today ... Drug Administration (FDA) to market Xpert® Flu . The ... simultaneously detects and differentiates Influenza A, Influenza B, and the ... (Photo:   http://photos.prnewswire.com/prnh/20110426/LA89263 ) "With Xpert ...
... CITY, April 26, 2011 AAPC ( www.aapc.com ) ... 30, and once again lowered prices from the previous year. Prices ... "While the primary purpose of a price reduction was to ... take advantage of the significant savings," said Olga Starynskaya, coding books ...
... MALVERN, Pa., April 25, 2011 Auxilium Pharmaceuticals, Inc. (NASDAQ: ... results for the first quarter 2011 on Monday, May 9, ... Company will also conduct a conference call that day at ... first quarter 2011.  The presentation slides to be used during ...
Cached Biology Technology:Cepheid Receives FDA Clearance for Xpert Flu, Delivering Simultaneous Detection and Differentiation of Flu A, Flu B, and 2009 H1N1 Strain 2Cepheid Receives FDA Clearance for Xpert Flu, Delivering Simultaneous Detection and Differentiation of Flu A, Flu B, and 2009 H1N1 Strain 3Cepheid Receives FDA Clearance for Xpert Flu, Delivering Simultaneous Detection and Differentiation of Flu A, Flu B, and 2009 H1N1 Strain 4AAPC Lowers Prices on Medical Coding Books, Again 2Auxilium Pharmaceuticals to Announce First Quarter 2011 Results and Conduct Conference Call on Monday, May 9, 2011 2Auxilium Pharmaceuticals to Announce First Quarter 2011 Results and Conduct Conference Call on Monday, May 9, 2011 3
Mouse monoclonal [M2II-12] to MRP2 ( Abpromise for all tested applications). entrezGeneID: 1244 SwissProtID: Q92887...
Mouse monoclonal antibody to ANAPC2 - anaphase promoting complex subunit 2...
... The MAX POWER 500V Programmable Power ... instruments which can handle virtually any ... high current blotting. It is unique ... displays. The MAX POWER Programmable Power ...
The Programmable MP-3500P-F Power Supply can be applied for any Microfluidic application....
Biology Products: