Navigation Links
The shape of things to come: NIST probes the promise of nanomanufacturing using DNA origami
Date:3/7/2012

In recent years, scientists have begun to harness DNA's powerful molecular machinery to build artificial structures at the nanoscale using the natural ability of pairs of DNA molecules to assemble into complex structures. Such "DNA origami," first developed at the California Institute of Technology,* could provide a means of assembling complex nanostructures such as semiconductor devices, sensors and drug delivery systems, from the bottom up.

While most researchers in the field are working to demonstrate what's possible, scientists at the National Institute of Standards and Technology (NIST) are seeking to determine what's practical.**

According to NIST researcher Alex Liddle, it's a lot like building with LEGOssome patterns enable the blocks to fit together snugly and stick together strongly and some don't.

"If the technology is actually going to be useful, you have to figure out how well it works," says Liddle. "We have determined what a number of the critical factors are for the specific case of assembling nanostructures using a DNA-origami template and have shown how proper design of the desired nanostructures is essential to achieving good yield, moving, we hope, the technology a step forward."

In DNA origami, researchers lay down a long thread of DNA and attach "staples" comprised of complementary strands that bind to make the DNA fold up into various shapes, including rectangles, squares and triangles. The shapes serve as a template onto which nanoscale objects such as nanoparticles and quantum dots can be attached using strings of linker molecules.

The NIST researchers measured how quickly nanoscale structures can be assembled using this technique, how precise the assembly process is, how closely they can be spaced, and the strength of the bonds between the nanoparticles and the DNA origami template.

What they found is that a simple structure, four quantum dots at the corners of a 70-nanometer by
'/>"/>

Contact: Mark Esser
mark.esser@nist.gov
301-975-8735
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Shape, fit of reproductive organs evolve quickly and in concert, leaving size behind
2. Researchers find best routes to self-assembling 3-D shapes
3. Dramatic diversity of columbine flowers explained by a simple change in cell shape
4. Bats show ability to change their ear shapes, making their hearing more flexible
5. Crater shapes explained, how carnivorous plants bite, and doubts about faster-than-light neutrinos
6. Long bone shape: A family affair
7. Shape memory materials ready for mass production
8. Scripps Research scientists pinpoint shape-shifting mechanism critical to protein signaling
9. Research offers new way to target shape-shifting proteins
10. UBC researchers discover key mechanism that regulates shape and growth of plants
11. What shapes a bone?
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
The shape of things to come: NIST probes the promise of nanomanufacturing using DNA origami
(Date:4/17/2014)... A drug under clinical trials to treat tuberculosis ... drugs that act against various bacteria, fungal infections and ... University of Illinois chemists and collaborators. , Led by ... determined the different ways the drug SQ109 attacks the ... target other pathogens from yeast to malaria and ...
(Date:4/17/2014)... 2014The development of stem cell therapies to cure a ... stem cell populations based on cell surface markers. Researchers ... marker that is highly expressed in a type of ... they describe in an article in BioResearch Open ... Inc., publishers. The article is available free on the ...
(Date:4/17/2014)... Luca Razzari of the nergie Matriaux Tlcommunications Research ... the John R. Evans Leaders Fund of the ... of state-of-the-art biotech and nanophotonics equipment. To this ... Ministre de l,Enseignement suprieur, de la Recherche, de ... new laboratories will help us develop new approaches ...
Breaking Biology News(10 mins):Multitarget TB drug could treat other diseases, evade resistance 2New state-of-the-art biotech and nanotech equipment for INRS 2
... often behave differently than temperate soils when being farmed. ... cultivated. With food shortages looming and soil quality declining ... and sub-tropical farming more productive and sustainable. New research ... a winter cover crop is most effective in retaining ...
... Georgia researchers have developed a new technology that ... from readily available non-food crops, such as Bermudagrass, ... "Producing ethanol from renewable biomass sources such as ... in large quantities," said Joy Peterson, professor of ...
... the U.S. will be overweight or obese by 2030, with ... $956.9 billion, according to researchers at the Johns Hopkins Bloomberg ... Quality and the University of Pennsylvania School of Medicine. Their ... Obesity . "National survey data show that the ...
Cached Biology News:New UGA biomass technology dramatically increases ethanol yield from grasses and yard waste 2New UGA biomass technology dramatically increases ethanol yield from grasses and yard waste 3Study suggests 86 percent of Americans could be overweight or obese by 2030 2
(Date:1/14/2014)... 2014  3D Communications, a leading provider of strategic communications services to ... events in the United States and ... Cox , JD, is returning to the firm,s Washington, ... 3D after more than two years of service as Associate Commissioner ...
(Date:1/14/2014)... Texas , Jan. 14, 2014 The ... and research medicinal plants and therapeutic derivatives thereof ... health professionals, and researchers about the challenges of ... http://photos.prnewswire.com/prnh/20100430/DC95601LOGO ) The Society ...
(Date:1/14/2014)... Toronto, Canada (PRWEB) January 14, 2014 ... and its motives and methods in product development and ... of the industry. This mistrust, fueled by concerns about ... further fed by reports of spectacular fines to the ...
(Date:1/14/2014)...   Kinaxis ®, provider of RapidResponse ®, a cloud-based ... planning ( S&OP ) service, is proud to be a ... be held at the Hilton San Diego Bayfront, January 30 ... Elisabeth Kaszas , Director of Supply Chain at Amgen, as ...
Breaking Biology Technology:Former FDA Associate Commissioner Returns To 3D Communications 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 2The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 3Event Alert: Kinaxis Customer to Present at the Biomanufacturing Summit "Supply Chain: Improving Network Effectiveness" 2
... WELLESLEY HILLS, Mass., Aug. 20 Joseph F. Finn, ... ("Spherics") for,the benefit of creditors, announced today that all ... auction on October 10,2008., One of the pieces ... Topiramate Extended Release, a once-a-day version of a,branded drug ...
... Bridge, a Boston-based interactive marketing and Web development firm recently ... - www.anikatherapeutics.com . Anika Therapeutics (NASDAQ: ANIK) develops products ... anti-adhesion markets. The company worked with Pixel Bridge to plan, ... ...
... have theorized a way to increase the speed of ... metal particles to well past the speed of light ... theory would use nanosized metal chains as building blocks ... at higher frequencies than conventional electronic circuits. Such ...
Cached Biology Technology:Spherics, Inc. Successful Bidder May Make MHRA Submission 2Pixel Bridge Works With Anika Therapeutics to Launch New Website 2Pixel Bridge Works With Anika Therapeutics to Launch New Website 3University of Pennsylvania scientists move optical computing closer to reality 2University of Pennsylvania scientists move optical computing closer to reality 3