Navigation Links
The secrets of a tadpole's tail and the implications for human healing
Date:1/13/2013

Scientists at The University of Manchester have made a surprising finding after studying how tadpoles re-grow their tails which could have big implications for research into human healing and regeneration.

It is generally appreciated that frogs and salamanders have remarkable regenerative capacities, in contrast to mammals, including humans. For example, if a tadpole loses its tail a new one will regenerate within a week. For several years Professor Enrique Amaya and his team at The Healing Foundation Centre in the Faculty of Life Sciences have been trying to better understand the regeneration process, in the hope of eventually using this information to find new therapies that will improve the ability of humans to heal and regenerate better.

In an earlier study, Professor Amaya's group identified which genes were activated during tail regeneration. Unexpectedly, that study showed that several genes that are involved in metabolism are activated, in particular those that are linked to the production of reactive oxygen species (ROS) - chemically reactive molecules containing oxygen. What was unusually about those findings is that ROS are commonly believed to be harmful to cells.

Professor Amaya and his group decided to follow up on this unexpected result and their new findings will be published in the next issue of Nature Cell Biology.

To examine ROS during tail regeneration, they measured the level of H2O2 (hydrogen peroxide, a common reactive oxygen species in cells) using a fluorescent molecule that changes light emission properties in the presence of H2O2. Using this advanced form of imaging, Professor Amaya and his group were able to show that a marked increase in H2O2 occurs following tail amputation and interestingly, they showed that the H2O2 levels remained elevated during the entire tail regeneration process, which lasts several days.

Talking about the research Professor Amaya says: "We were very surpr
'/>"/>

Contact: Morwenna Grills
Morwenna.Grills@manchester.ac.uk
44-161-275-2111
University of Manchester
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Secrets of gentle touch revealed
2. Biologists unlocking the secrets of plant defenses, 1 piece at a time
3. Pond skating insects reveal water-walking secrets
4. Biophysicists unravel secrets of genetic switch
5. Ancient genome reveals its secrets
6. New model gives hands-on help for learning the secrets of molecules
7. Decoding the secrets of balance
8. Hidden secrets in the worlds most northerly rainforests
9. Large, medically important class of proteins starts to yield its secrets
10. Rensselaer scientists unlock some key secrets of photosynthesis
11. Track Atlantic bluefin tuna to learn migration, habitat secrets
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2014)... International Glossina Genome Initiative (IGGI) has produced the first ... morsitans . The blood-sucking insect is the sole transmitter ... sub-Saharan Africa. The vast store of genetic data will ... and provide insights into the tsetse fly,s unique biology. ... insect world: it feeds exclusively on the blood of ...
(Date:4/24/2014)... Publishing recently introduced Clinical OMICs ... application of OMICs technologies in clinical settings. These ... to transform medical care just as they revolutionized ... , "GEN,s editors and reporters have written about ... etc. etc. for years," said John Sterling, editor-in-chief ...
(Date:4/24/2014)... research led by Alison Allan, PhD, a scientist at ... why breast cancer often spreads or metastasizes to the ... cancer and the number two cause of cancer-related deaths ... traditional chemotherapy and radiation have a high success rate, ... conventional treatments fail. In particular, the lung is one ...
Breaking Biology News(10 mins):Genetic code of the deadly tsetse fly unraveled 2New study helps to explain why breast cancer often spreads to the lung 2
... NY In the neuromuscular disease called spinal muscular ... single gene mutation leads to serious damage in growing ... Now, in laboratory experiments, researchers at Cold Spring Harbor ... replenish the protein by activating an existing, slightly modified ...
... WI, APRIL 4, 2008 The American Society ... (CSSA), and Soil Science Society of America (SSSA) ... as part of the 2008 National Student Recognition ... the Societies news magazine. The 2008 National ...
... some people are born with silver spoons in their ... of the animal world, according to research done in ... of female red squirrels in Kluane, Yukon, revealed that ... spring temperature experienced between birth and weaning could reflect ...
Cached Biology News:Cold Spring Harbor Laboratory scientists devise potential approach to treat spinal muscular atrophy 2Outstanding undergraduates recognized in agronomy, crop, soil, and environmental sciences 2
(Date:1/15/2014)... , January 15, 2014 A study has ... on the Formula 1 track could help to tackle the ... Technologies (MAT), Stowhealth (a GP surgery based in Stowmarket) and ... provider Simplyhealth. Telemetry technology, which is inspired by ...
(Date:1/15/2014)... 2014 DTS Language Services, Inc . ... Portal for Life Science organizations who need document translations. ... matter of their documents in advance with a selection of ... of translations, often a critical factor in clinical and scientific ...
(Date:1/15/2014)... TAIPEI , Jan. 15, 2014 TaiGen Biotechnology ... an exclusive agreement with R-Pharm, a leading Russian pharmaceutical ... in the Russian Federation , ... Commonwealth Independent States (CIS). Nemonoxacin is a novel antibiotic for ...
(Date:1/14/2014)...  3D Communications, a leading provider of strategic communications services to corporations ... in the United States and ... , JD, is returning to the firm,s Washington, D.C. ... after more than two years of service as Associate Commissioner for ...
Breaking Biology Technology:Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4DTS Improves Efficiency for Life Science Document Translations 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Former FDA Associate Commissioner Returns To 3D Communications 2
... Zentaris Inc.,(NASDAQ: AEZS , TSX: AEZ), a ... will announce its third quarter 2008,financial and operating ... a.m.,The Company will host a conference call and ... at 10:00 a.m., Eastern Time., Participants may ...
... -- China Shenghuo,Pharmaceutical Holdings, Inc. (Amex: ... is engaged in the research, development, manufacture, ... products,in the People,s Republic of China, today ... the American Stock Exchange) (the "Exchange") has ...
... Make Diabetes a Smaller Part of Life, BEDFORD, ... the leader in patch pump technology with its OmniPod(R),Insulin ... Part of Your Life, video contest. The competition begins ... all current OmniPod users.,Entrants are invited to create a ...
Cached Biology Technology:NYSE Alternext US Accepts China Shenghuo's Compliance Plan for Continued Listing 2NYSE Alternext US Accepts China Shenghuo's Compliance Plan for Continued Listing 3NYSE Alternext US Accepts China Shenghuo's Compliance Plan for Continued Listing 4Video: Insulet Unveils Video Contest for OmniPod Users 2Video: Insulet Unveils Video Contest for OmniPod Users 3
Request Info...
NATIVE RAT OSTEOCALCIN...
... Chicken polyclonal to Opsin 1 ( Abpromise ... Antigen: Synthetic peptide: YEDSTHASIFTYT, corresponding to amino ... and synthetic peptide corresponding to amino acids 18/30 ... and used as immunogen. Entrez ...
EnzChek Ultra Xylanase Assay Kit *500 assays*...
Biology Products: