Navigation Links
'The pill' for him: Scientists find a hormonal on-and-off switch for male fertility
Date:11/30/2009

A new research report published in the December 2009 print issue of The FASEB Journal could one day give men similar type of control over their fertility that women have had since the 1960s. That's because scientists have found how and where androgenic hormones work in the testis to control normal sperm production and male fertility. This opens a promising avenue for the development of "the pill" for men. The discovery also offers hope to those who cannot have children because of low sperm counts. Although the research was conducted in mice, a similar effect is likely to obtain in other mammals, such as humans.

"This study provides a new opportunity to identify how androgens control sperm production, which could provide new insight for the development of new treatments for male infertility and perhaps new male contraceptives," said Michelle Welsh, Ph.D., co-author of the study, from the Centre for Reproductive Biology at The Queen's Medical Research Institute in Edinburgh, UK.

To make this discovery, Welsh and colleagues performed studies in two groups of mice. The first group of mice was normal, but the second group of mice was missing a gene from the peritubular myoid cells in the testis. This gene that was missing codes for the androgen hormone receptor, and when missing, sperm production was significantly decreased when compared to the normal group. The result was infertility.

"Although 'the pill' arguably has been liberating for women since its development in the 1960s, a similar birth control drug for men has been elusive," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "Not only does this research pinpoint androgenic hormones and their cellular receptors as prime targets for the development of new birth control drugs, but it promises to speed the development of new agents to boost sperm production."


'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1

Related biology news :

1. Prolonged respiratory problems for oil spill clean-up volunteers
2. First wind turbines on Galapagos Islands will halve diesel imports, reduce risk of future oil spills
3. The surprising power of the pill
4. A bitter pill to swallow
5. Milkweeds evolutionary approach to caterpillars: Counter appetite with fast repair
6. Research shows that the pill does not deserve its reputation for causing weight gain
7. Genes determine whether sugar pills work
8. Capillary mats labor-saving, economical alternative to hand watering
9. Cleaning up oil spills can kill more fish than spills themselves, say Queens biologists
10. Arctic governments and industry still unprepared for oil spills 20 years after Exxon Valdez
11. The Prestige oil spill caused changes in the cell structure of mussels
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2015)...   HOYOS Labs , a leading global authentication ... the Company will demonstrate multiple biometrics-based technologies under its ... Connect:ID on March 23 through 25, 2015, in ... the IEEE Biometric Open Protocol Standard; free biometrics-based consumer ... control system. BOPS was invented by HOYOS Labs and ...
(Date:3/20/2015)... OXFORD, Conn. , March 20, 2015 ... "Company"), a biometric authentication company focused on the growing ... Wocket® smart wallet is one of the products featured ... today, March 20th at 11:00 PM EST on the ... travels to Las Vegas , site ...
(Date:3/17/2015)... , March 17, 2015 Emotient, the ... software, today announced general availability of Emotient ... for the analysis of facial expressions. The system ... media content, products and services. It delivers audience ... and sentiment - as derived from facial evidence ...
Breaking Biology News(10 mins):HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 3NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 2NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 3New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 2New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 3New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 4
... French . Some of the human X chromosome ... Africa, according to an international team of researchers led by ... of Montreal and the CHU Sainte-Justine Research Center. The research ... and Evolution. "This confirms recent findings suggesting ...
... July 18, 2011 Researchers at UT Southwestern Medical ... involved in the formation of colon cancer, far more ... study, published in the July 2011 Cancer Research (Priority ... cancer treatments targeting multiple genes and pathways simultaneously. Current ...
... YORK, July 16, 2011 Experts from the Center ... Center will present new research at the 2011 Alzheimer,s ... in Paris, France from July 16 21. ... impairment in retired football players, with Stella Karantzoulis, PhD, ...
Cached Biology News:Genetic research confirms that non-Africans are part Neanderthal 2NYU Langone Medical Center's tip sheet to the 2011 Alzheimer's Association International Conference 2NYU Langone Medical Center's tip sheet to the 2011 Alzheimer's Association International Conference 3NYU Langone Medical Center's tip sheet to the 2011 Alzheimer's Association International Conference 4NYU Langone Medical Center's tip sheet to the 2011 Alzheimer's Association International Conference 5NYU Langone Medical Center's tip sheet to the 2011 Alzheimer's Association International Conference 6
(Date:3/26/2015)... WriteResult, a premier provider of ePRO ... University’s School of Public Health and New Haven Farms ... 4 month-long project. The goal of the study was ... with free access to fresh produce and nutrition education ... like high blood pressure, diabetes and weight gain. Patients ...
(Date:3/25/2015)... -- Optimal Research, LLC has been nominated as a ... Clinical Site or Trial Network". This is ... as a nominee in this ViE award category at ... in 2014. The ViE awards were created to honor ... contributions of companies and individuals in the vaccine industry. ...
(Date:3/25/2015)... 2015 Accelovance, a therapeutically focused contract research ... Contract Research Organization" at the upcoming Vaccine Industry Excellence ... This is the eighth consecutive year Accelovance ... winning for "Best Contract Research Organization" in 2009, 2010, ... 2013. "We,re excited to be a finalist ...
(Date:3/25/2015)... Francisco, CA (PRWEB) March 25, 2015 ... Support for Novel Mechanism of Action in Neuromuscular ... 25, 2015 – Cytokinetics, Incorporated (Nasdaq: CYTK) announced ... fast skeletal muscle troponin activator tirasemtiv in the ... a Phase IIa “Evidence of Effect” or hypothesis-generating ...
Breaking Biology Technology:Yale and New Haven Farms Improving Patient Health with WriteResult's myPROpad™ 2Yale and New Haven Farms Improving Patient Health with WriteResult's myPROpad™ 3Optimal Research Nominated 2015 Vaccine Industry Excellence (ViE) Award 2Accelovance Nominated for 2015 Vaccine Industry Excellence (ViE) Awards 2Cytokinetics Announces Publication of Results from Phase II Trial of Tirasemtiv in Patients with Myasthenia Gravis 2Cytokinetics Announces Publication of Results from Phase II Trial of Tirasemtiv in Patients with Myasthenia Gravis 3Cytokinetics Announces Publication of Results from Phase II Trial of Tirasemtiv in Patients with Myasthenia Gravis 4Cytokinetics Announces Publication of Results from Phase II Trial of Tirasemtiv in Patients with Myasthenia Gravis 5Cytokinetics Announces Publication of Results from Phase II Trial of Tirasemtiv in Patients with Myasthenia Gravis 6
... pleaded guilty in Milwaukee to charges of criminal copyright ... million in counterfeit Rockwell Automation computer software ... Fisher for the Criminal Division and U.S. Attorney Steven ... announced that Robert Koster of Jonesboro, Ark. pleaded guilty ...
... appears that Wisconsin has failed in its bid to lure a ... a maker of neural stem cell kits for researchers, apparently has ... it was spun out of the University of Georgia . ... likely that the company will remain in Georgia, despite an incentive ...
... (For a translation, scroll to the end). The online retailing ... modifying their steps as the Internet changes everything. , ... adopted at least some of these changes (both good and ... interact with each other, or buy and sell goods and ...
Cached Biology Technology:Two convicted of selling $6 million in counterfeit Rockwell software on eBay 2Georgia stem cell company likely to stay put 2Online retailing "tango" is adding some steps 2Online retailing "tango" is adding some steps 3Online retailing "tango" is adding some steps 4Online retailing "tango" is adding some steps 5Online retailing "tango" is adding some steps 6
... protein assay reagents package is used for determining ... and detergents. The RC DC protein assay is ... for 500 standard assays: 250 ml RC reagent ... alkaline copper tartrate solution, 2 L dilute Folin ...
... modification that plays an important role ... inflammation, cell-to-cell adhesion, and cell signaling. ... based Glycoprotein Isolation Kits, Concanavalin A ... that allow isolation of glycoproteins from ...
... and PowerPac Basic power supply are used for ... Trans-Blot cell accommodates two 7.5 x 10 cm ... electrode assembly, Bio-Ice cooling unit, buffer tank, lid ... PowerPac basic power supply, 100-120 and 220-240 V, ...
... provides the sensitivity and versatility you expect ... photon counting with selected photomultipliers ensure superior ... Equipped with up to 2 reagent injectors ... gene assays as well as other luminescence ...
Biology Products: