Navigation Links
'The pill' for him: Scientists find a hormonal on-and-off switch for male fertility
Date:11/30/2009

A new research report published in the December 2009 print issue of The FASEB Journal could one day give men similar type of control over their fertility that women have had since the 1960s. That's because scientists have found how and where androgenic hormones work in the testis to control normal sperm production and male fertility. This opens a promising avenue for the development of "the pill" for men. The discovery also offers hope to those who cannot have children because of low sperm counts. Although the research was conducted in mice, a similar effect is likely to obtain in other mammals, such as humans.

"This study provides a new opportunity to identify how androgens control sperm production, which could provide new insight for the development of new treatments for male infertility and perhaps new male contraceptives," said Michelle Welsh, Ph.D., co-author of the study, from the Centre for Reproductive Biology at The Queen's Medical Research Institute in Edinburgh, UK.

To make this discovery, Welsh and colleagues performed studies in two groups of mice. The first group of mice was normal, but the second group of mice was missing a gene from the peritubular myoid cells in the testis. This gene that was missing codes for the androgen hormone receptor, and when missing, sperm production was significantly decreased when compared to the normal group. The result was infertility.

"Although 'the pill' arguably has been liberating for women since its development in the 1960s, a similar birth control drug for men has been elusive," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "Not only does this research pinpoint androgenic hormones and their cellular receptors as prime targets for the development of new birth control drugs, but it promises to speed the development of new agents to boost sperm production."


'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1

Related biology news :

1. Prolonged respiratory problems for oil spill clean-up volunteers
2. First wind turbines on Galapagos Islands will halve diesel imports, reduce risk of future oil spills
3. The surprising power of the pill
4. A bitter pill to swallow
5. Milkweeds evolutionary approach to caterpillars: Counter appetite with fast repair
6. Research shows that the pill does not deserve its reputation for causing weight gain
7. Genes determine whether sugar pills work
8. Capillary mats labor-saving, economical alternative to hand watering
9. Cleaning up oil spills can kill more fish than spills themselves, say Queens biologists
10. Arctic governments and industry still unprepared for oil spills 20 years after Exxon Valdez
11. The Prestige oil spill caused changes in the cell structure of mussels
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/4/2017)...   EyeLock LLC , a leader of iris-based ... Patent and Trademark Office (USPTO) has issued U.S. Patent ... an iris image with a face image acquired in ... 45 th issued patent. "The ... the multi-modal biometric capabilities that have recently come to ...
(Date:3/30/2017)... LOS ANGELES , March 30, 2017  On ... Hack the Genome hackathon at ... This exciting two-day competition will focus on developing health ... experience. Hack the Genome is ... has been tremendous. The world,s largest companies in the ...
(Date:3/30/2017)... -- Trends, opportunities and forecast in this market to ... AFIS, iris recognition, facial recognition, hand geometry, vein recognition, ... industry (government and law enforcement, commercial and retail, health ... and by region ( North America , ... , and the Rest of the World) ...
Breaking Biology News(10 mins):
(Date:9/20/2017)... ... September 20, 2017 , ... Cybrexa Therapeutics , ... to the role of chief scientific officer. In this role, Dr. Paralkar will ... president and CEO, Per Hellsund. , “I was impressed with Cybrexa’s revolutionary technology ...
(Date:9/20/2017)... ... September 20, 2017 , ... Proscia Inc. , a ... provider of whole slide imaging solutions, are hosting a pre-conference workshop at the ... Deploying a Best-in-Class Strategy for Digital Pathology,” will feature Proscia CEO, David West ...
(Date:9/20/2017)... ... September 20, 2017 , ... Foresight Institute, a leading ... transformative technologies, announced the winners for the 2017 Foresight Institute Feynman Prizes.These are ... nanotechnology/molecular manufacturing. , Established in 1993 and named in honor of pioneer physicist ...
(Date:9/19/2017)... ... 2017 , ... Participants of this educational webinar will learn ... with the advantages and disadvantages of ductless, filtered fume hoods, they will also ... , Attendees will learn from an industry expert about the different types of ...
Breaking Biology Technology: