Navigation Links
The pathway to potato poisons
Date:7/31/2013

In 1924, Science magazine reported on a fatal case of potato poisoning: James B. Matheney of Vandalia, Illinois, had gathered about one and a half bushels of tubers, which had turned green due to sunlight exposure. Two days after eating the potatoes, most of his family -- wife, two daughters and four sons -- showed symptoms of poisoning; the only exceptions were James himself, who didn't eat the potatoes, and a breast-fed baby boy. His wife, aged 45, died a week later, followed by their 16-year-old daughter. The other five members of the family recovered.

Although such fatalities are rare among human beings, farm animals often get sick or die after eating green potatoes. Symptoms include damage to the digestive system as well as loss of sensation, hallucinations and other neurological disturbances. Death can be caused by a disruption of the heart beat. The culprits are the toxic substances solanine and chaconine; their concentration rises sharply with exposure to light or during sprouting, and they protect the tubers from insects and disease.

Solanine and chaconine belong to the large family of glycoalkaloids, which includes thousands of toxins found in small amounts in other edible plants, including tomatoes and eggplant. These substances have been known for over 200 years, but only recently has Prof. Asaph Aharoni of the Plant Sciences Department begun to unravel how they are produced in plants. He and his team have mapped out the biochemical pathway responsible for manufacturing glycoalkaloids from cholesterol. Their findings will facilitate the breeding of toxin-free crops and the development of new crop varieties from wild strains that contain such large amounts of glycoalkaloids, they are currently considered inedible. On the other hand, causing plants to produce glycoalkaloids if they don't do so naturally or increasing their glycoalkaloid content can help protect them against disease.

Two years ago, in research reported
'/>"/>

Contact: Yivsam Azgad
news@weizmann.ac.il
972-893-43856
Weizmann Institute of Science
Source:Eurekalert

Page: 1 2

Related biology news :

1. A maternal junk food diet alters development of opioid pathway in the offspring
2. Haste and waste on neuronal pathways
3. New gut microbiome research to explore red meat -- colorectal cancer pathway
4. Signalling pathways meeting targeting the HER/EGFR family: Focus on breast, lung and colorectal cancers
5. Signaling pathway linked to fetal alcohol risk
6. Pathway for membrane building blocks
7. Thomas Jefferson University researchers discover new pathways that drive metastatic prostate cancer
8. Long-distance solute transport in trees improved by intercellular pathways in living woody tissues
9. Researchers find new genetic pathway behind neurodevelopmental disorders
10. Discovery of pathway leading to depression reveals new drug targets
11. Discovery of molecular pathway of Alzheimers disease reveals new drug targets
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... and Markets ( http://www.researchandmarkets.com/research/8kmfcn/iphone_5s ) has announced ... - Apple/AuthenTec TMDR92 & Sapphire - Technology Report" ... http://photos.prnewswire.com/prnh/20130307/600769 Following the acquisition of AuthenTec ... with the iPhone 5S. It is currently the only ...
(Date:12/19/2014)... 18, 2014  23andMe, Inc., the leading personal genetics company, today ... in genetic ancestry of individuals from across the ... more than four hundred years ago, the United ... peoples from different continents. This study illuminates how American history ...
(Date:12/17/2014)... , Dec. 15, 2014 Research and Markets ... "Samsung Galaxy S5 - Home Button Synaptics Fingerprint ... http://photos.prnewswire.com/prnh/20130307/600769 Based ... 5S, Samsung introduces for the first time a fingerprint ...
Breaking Biology News(10 mins):iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 & Sapphire - Technology Report 223andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2
... February 27, 2012 In a study published in ... the American Academy of Child and Adolescent Psychiatry , ... Children,s Healthcare of Atlanta, and Emory University School of ... cognitive and social disability in children with autism spectrum ...
... to be human in the face of emerging technologies ... hosts Emerge. An unparalleled campus-wide collaboration, Emerge unites ... designers to build, draw, write and rethink the future ... share. Leaders from industry and prominent authors and ...
... that there is a genetic component to intelligence, but a ... genes thought to be linked to intelligence are probably not ... roots may still be a long way off. ... Professor of Economics, and Christopher F. Chabris ,88, PhD ,99, ...
Cached Biology News:Eye-tracking reveals variability in successful social strategies for children with autism 2Emerge attracts futurists to collaborate with scientists, designers artists is redesign of future 2Emerge attracts futurists to collaborate with scientists, designers artists is redesign of future 3In the genes, but which ones? 2In the genes, but which ones? 3
(Date:1/22/2015)... Madison, WI (PRWEB) January 22, 2015 Dr. ... at the 12th annual Scripps Natural Supplements Pre-Conference seminar on ... Supplements Conference is an annual continuing education conference for health ... 15th and included the topic of probiotics in health. Dr. ...
(Date:1/22/2015)... Jan. 22, 2015   Cypher Genomics, Inc., ... (NASDAQ: SQNM ), the leading molecular ... next generation noninvasive prenatal tests (NIPT). Through this ... called Mantis™, to advance analysis of clinically-relevant fetal ...
(Date:12/24/2014)... SILVER SPRING, Md. , Dec. 24, 2014  United ... that Medtronic, Inc. (NYSE: MDT ) has ... and Drug Administration (FDA) for the use of Medtronic,s ... a newly developed catheter) for use with United Therapeutics, ...
(Date:12/24/2014)... GMO corn cases filed across the United States, and ... being consolidated in a Kansas federal court for pretrial proceedings. ... Corn Litigation, MDL No. 2591 in the U.S. District Court ... GMO corn multidistrict litigation (MDL) has been handed over to ...
Breaking Biology Technology:Cypher Genomics and Sequenom Announce Development Agreement 2Cypher Genomics and Sequenom Announce Development Agreement 3Cypher Genomics and Sequenom Announce Development Agreement 4United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 3United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 4Carey Danis & Lowe Reports on Syngenta GMO Corn Transfer Order 2
... San Antonio (June 30, 2008) Researchers at The University ... Emerging Infectious Diseases and The University of Texas Health Science ... believed to play a role in controlling the early infectious ... bioterrorism agent that is the cause of tularemia. The findings ...
... Fla. -- Researchers have devised an inexpensive way to ... heat energy generated by the sun and other sources. ... Idaho National Laboratory, is the first step toward a ... materials. , While methods to convert the energy into ...
... /PRNewswire-FirstCall/ - Chromos Molecular,Systems Inc. ("Chromos" or ... of British Columbia has issued an interim ... in connection with the previously announced proposed,plan ... the,Company, Calyx Bio-Ventures Inc. ("Calyx"), a wholly-owned ...
Cached Biology Technology:UTSA/UTHSCSA publish results on bio-threat agent 2Flexible nanoantenna arrays capture abundant solar energy 2Flexible nanoantenna arrays capture abundant solar energy 3Chromos obtains interim order in connection with arrangement, announces annual and special meeting of shareholders and confirms mailing of information circular 2Chromos obtains interim order in connection with arrangement, announces annual and special meeting of shareholders and confirms mailing of information circular 3