Navigation Links
The next era in discovering drugs in nature's own medicine cabinet
Date:9/4/2013

New technology for discovering antibiotics, anti-cancer drugs and other medicines inside soil microbes and other natural sources is reviving a treasure hunt that already has given humanity more than 50 percent of today's prescription drugs. This new era in "bioprospecting" is the topic of the cover story in Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society.

Lisa M. Jarvis, C&EN senior editor, points out that natural products are the source of about half of the modern drugs approved in the U.S. But the search for new products slowed as drug companies learned to make synthetic compounds at high speeds by the thousands. Now, the increasing availability and affordability of DNA sequencing is reviving activity in the field. It enables scientists to sample the DNA of thousands of microbes at once in search of gene clusters that could yield a new drug. Then computer models can figure out what molecules the genes encode, and organize the information in searchable databases.

The potential for discovering new medicines is high enough to attract the attention and millions of dollars in investments of some of the pharmaceutical industry's major players, including Sanofi and Novartis. The article notes that the latest research has significantly increased the number of microbial compounds being discovered and has opened a window on a vast new library of genes and gene clusters that code for previously undiscovered drugs. The flood of genetic discovery underpins expectations that potential new medicines based on natural products will be in clinical trials in humans within a few years.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Researchers develop tools for discovering new species
2. Discovering cell surface proteins behavior
3. Drug design success propels efforts to fight HIV with a combination of 2 FDA-approved drugs
4. First update in a century in testing drugs for elemental impurities
5. New drugs to find the right target to fight Alzheimers disease
6. Alternative target for breast cancer drugs
7. Toward broad-spectrum antiviral drugs for common cold and other infections
8. Gene variants may predict who will benefit from breast cancer prevention drugs
9. New screening technique paves the way for protein drugs from bacteria
10. Soda and illegal drugs cause similar damage to teeth
11. A new strategy required in the search for Alzheimers drugs?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... DUBLIN , Apr. 11, 2017 Research ... Tracking Market 2017-2021" report to their offering. ... The global eye tracking market to grow at ... The report, Global Eye Tracking Market 2017-2021, has been prepared based ... report covers the market landscape and its growth prospects over the ...
(Date:4/5/2017)... 5, 2017  The Allen Institute for Cell Science ... a one-of-a-kind portal and dynamic digital window into the ... the first application of deep learning to create predictive ... lines and a growing suite of powerful tools. The ... and future publicly available resources created and shared by ...
(Date:4/3/2017)... April 3, 2017  Data captured by ... platform, detected a statistically significant association between ... to treatment and objective response of cancer ... to predict whether cancer patients will respond ... as well as to improve both pre-infusion potency ...
Breaking Biology News(10 mins):
(Date:8/15/2017)... ... August 15, 2017 , ... Any expert in stem cell research or ... for more than half a century. Despite their essential roles in human health ... known that molecular tags developed for this purpose also tag other, more abundant, non-stem ...
(Date:8/15/2017)... ... August 15, 2017 , ... JULABO USA ... responsive, the new website makes it easy to navigate through the site whether ... now find detailed product information, educational industry content and visit the company’s social ...
(Date:8/11/2017)... 11, 2017  Market researcher Kalorama Information ... article regarding the telemedicine market.  The telemedicine ... Information.  The article, "Heart and Asthma ...  used information from Kalorama Information,s Remote Patient ... Market  (Sleep, Diabetes, Vital Signs /EKG ...
(Date:8/10/2017)... ... August 09, 2017 , ... As a full-service ... its ideal customers with the right message. Their effective, cutting-edge inbound marketing strategies ... we realize how crucial the agriculture industry is,” said David Phelps, chief marketing ...
Breaking Biology Technology: