Navigation Links
The next era in discovering drugs in nature's own medicine cabinet

New technology for discovering antibiotics, anti-cancer drugs and other medicines inside soil microbes and other natural sources is reviving a treasure hunt that already has given humanity more than 50 percent of today's prescription drugs. This new era in "bioprospecting" is the topic of the cover story in Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society.

Lisa M. Jarvis, C&EN senior editor, points out that natural products are the source of about half of the modern drugs approved in the U.S. But the search for new products slowed as drug companies learned to make synthetic compounds at high speeds by the thousands. Now, the increasing availability and affordability of DNA sequencing is reviving activity in the field. It enables scientists to sample the DNA of thousands of microbes at once in search of gene clusters that could yield a new drug. Then computer models can figure out what molecules the genes encode, and organize the information in searchable databases.

The potential for discovering new medicines is high enough to attract the attention and millions of dollars in investments of some of the pharmaceutical industry's major players, including Sanofi and Novartis. The article notes that the latest research has significantly increased the number of microbial compounds being discovered and has opened a window on a vast new library of genes and gene clusters that code for previously undiscovered drugs. The flood of genetic discovery underpins expectations that potential new medicines based on natural products will be in clinical trials in humans within a few years.


Contact: Michael Bernstein
American Chemical Society

Page: 1

Related biology news :

1. Researchers develop tools for discovering new species
2. Discovering cell surface proteins behavior
3. Drug design success propels efforts to fight HIV with a combination of 2 FDA-approved drugs
4. First update in a century in testing drugs for elemental impurities
5. New drugs to find the right target to fight Alzheimers disease
6. Alternative target for breast cancer drugs
7. Toward broad-spectrum antiviral drugs for common cold and other infections
8. Gene variants may predict who will benefit from breast cancer prevention drugs
9. New screening technique paves the way for protein drugs from bacteria
10. Soda and illegal drugs cause similar damage to teeth
11. A new strategy required in the search for Alzheimers drugs?
Post Your Comments:
(Date:9/24/2015)... 24, 2015  EyeLock LLC, a market leader of ... winning and latest technology in Booth #602 at next ... . EyeLock,s iris authentication technology provides an ... accuracy, making it the most proven way to authenticate ... technology to deliver a fast and friendly user experience ...
(Date:9/10/2015)... 2015 Report Details Emerging ... Opportunities and Revenue Prospects to Help You Stay ... especially new drug classes? Get the latest technological ... exclusive market data and industry knowledge, benefitting your ... opportunities and sales predictions. Visiongain,s new study ...
(Date:9/10/2015)...  NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... growing mobile commerce market, announces that the ... Modern, will feature the Wocket® smart wallet for the ... Touch Of Modern is an online ... to its 7.2 million members. Customers are affluent, urban ...
Breaking Biology News(10 mins):
(Date:10/13/2015)... (PRWEB) , ... October 13, 2015 , ... ... high-quality recombinant antibodies, today announced that it has received a Phase I Small ... administered by the National Institute of General Medical Sciences (NIGMS), will fund the ...
(Date:10/13/2015)... --      Q BioMed Inc (OTC: QBIO), ... a strategic relationship with Wombat Capital, Ltd., a ... France based strategic and scientific advisory firm.. ... collaborative arrangement gives Q BioMed and its stakeholders access ... as long established pharmaceutical industry relationships. The advisors within ...
(Date:10/13/2015)...  According to Kalorama Information, the global market ... by the end of 2015. Clinical laboratories are ... it is estimated that approximately 80% of physicians, ... addition to diagnosing patients, clinical lab testing may ... drug treatment and conditions, and determine individual therapy. ...
(Date:10/13/2015)... (PRWEB) , ... October 13, 2015 , ... ... and distributor of automation systems, material handling solutions and components, is opening its ... I-94 near State Street, the facility is Exotic’s second major expansion in Metropolitan ...
Breaking Biology Technology: