Navigation Links
The neuroscience of finding your lost keys
Date:3/21/2013

LA JOLLA, CA----Ever find yourself racking your brain on a Monday morning to remember where you put your car keys?

When you do find those keys, you can thank the hippocampus, a brain region responsible for storing and retrieving memories of different environments-such as that room where your keys were hiding in an unusual spot.

Now, scientists at the Salk Institute for Biological Studies have helped explain how the brain keeps track of the incredibly rich and complex environments people navigate on a daily basis. They discovered how the dentate gyrus, a subregion of the hippocampus, helps keep memories of similar events and environments separate, a finding they reported March 20 in eLife. The findings, which clarify how the brain stores and distinguishes between memories, may also help identify how neurodegenerative diseases, such as Alzheimer's disease, rob people of these abilities.

"Everyday, we have to remember subtle differences between how things are today, versus how they were yesterday - from where we parked our car to where we left our cellphone," says Fred H. Gage, senior author on the paper and the Vi and John Adler Chair for Research on Age-Related Neurodegenerative Disease at Salk. "We found how the brain makes these distinctions, by storing separate 'recordings' of each environment in the dentate gyrus."

The process of taking complex memories and converting them into representations that are less easily confused is known as pattern separation. Computational models of brain function suggest that the dentate gyrus helps us perform pattern separation of memories by activating different groups of neurons when an animal is in different environments.

However, previous laboratory studies found that in fact the same populations of neurons in the dentate gyrus are active in different environments, and that the way the cells distinguished new surroundings was by changing the rate at which they sent elec
'/>"/>

Contact: Andy Hoang
ahoang@salk.edu
619-861-5811
Salk Institute
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Scripps Florida scientist awarded prestigious Javits Neuroscience Investigator Award
2. RayBiotech, Inc. Executes Neuroscience Biomarker Master Services Agreement with Banner Sun Health Research Institute
3. Neuroscience: The extraordinary ease of ordinal series
4. Media registration opens for Neuroscience 2012, worlds largest brain science meeting
5. Wiring bats for neuroscience research
6. UCSF pair win Gruber Foundation Neuroscience prize
7. 6th Annual Canadian Neuroscience Meeting, Vancouver, May 20-23, 2012
8. Stanford and MIT scientists win Perl-UNC Neuroscience prize
9. ACMG releases report on incidental findings in clinical exome and genome sequencing
10. Finding Mr. Right, how insects sniff out the perfect mate
11. Finding the way to memory
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
The neuroscience of finding your lost keys
(Date:4/17/2014)... for chili peppers. Information about archaeological remains of ancient ... the appearance of words for chili peppers in ancient ... and highlight the value of multi-proxy data analysis. Their ... nine papers presented in a special feature issue of ... on plant and animal domestication edited by Dolores ...
(Date:4/17/2014)... anthrax detection cartridge developed at Sandia National Laboratories and ... easier, faster and cheaper. , Bacillus anthracis ... in soils all over the world and can cause ... animals. The bacteria can survive in harsh conditions for ... may occur through skin contact, inhalation of spores or ...
(Date:4/17/2014)... ago, Katia Silvera , a postdoctoral scholar at the ... field trip in a mountainous area in central Panama when ... , Unable to identify it, they contacted German Carnevali, a ... be an unnamed species. So Carnevali recently named it after ... genus name, comprising about 40 species in the world. ...
Breaking Biology News(10 mins):Chickens to chili peppers 2Chickens to chili peppers 3Pocket-sized anthrax detector aids global agriculture 2Pocket-sized anthrax detector aids global agriculture 3Orchid named after UC Riverside researcher 2Orchid named after UC Riverside researcher 3
... Seals shiver when exposed to cold air but not ... believe allows the diving seal to conserve oxygen and ... , The researchers presented the study at The American ... Virginia Beach, Va., October 8-11. The researchers, Arnoldus Schytte ...
... nucleolus resides deep within the cell nucleus and performs ... ribosomes, the molecular machines that convert the genetic information ... work of life. , Gary Karpen and Jamy ... Department of Energy's Lawrence Berkeley National Laboratory, have now ...
... to treating severe nerve pain ?by aiming drugs at a ... Utah scientists who study the venoms of deadly, sea-dwelling cone ... treat a chronic and debilitating form of pain suffered by ... McIntosh, a University of Utah research professor of biology, and ...
Cached Biology News:Seals protect brain, conserve oxygen by turning off shivering response on icy dives 2Seals protect brain, conserve oxygen by turning off shivering response on icy dives 3Regulating the nuclear architecture of the cell 2Regulating the nuclear architecture of the cell 3Regulating the nuclear architecture of the cell 4Regulating the nuclear architecture of the cell 5A new target for painkillers 2A new target for painkillers 3A new target for painkillers 4
(Date:1/15/2014)... (PRWEB) January 15, 2014 DTS Language ... its Online Web Portal for Life Science organizations who need ... specify the subject matter of their documents in advance with ... help reduce time-to-delivery of translations, often a critical factor in ...
(Date:1/15/2014)... 15, 2014 TaiGen Biotechnology Company, Limited ("TaiGen") today ... R-Pharm, a leading Russian pharmaceutical company, to develop and ... Russian Federation , Turkey ... is a novel antibiotic for the treatment of bacterial ...
(Date:1/14/2014)... , Jan. 14, 2014  3D Communications, a leading provider of strategic ... business, and media events in the United States ... associate Virginia Cox , JD, is returning to the firm,s ... Cox re-joins 3D after more than two years of service ...
(Date:1/14/2014)... BETHESDA, Md. , Jan. 14, 2014  Organovo announced ... from the National Institutes of Health (NIH) to help ... effective treatments to patients on a faster timeline. Organovo ... Sciences (NCATS) and the National Eye Institute (NEI) to ...
Breaking Biology Technology:DTS Improves Efficiency for Life Science Document Translations 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Former FDA Associate Commissioner Returns To 3D Communications 2Organovo Announces Collaboration with National Institutes of Health 2Organovo Announces Collaboration with National Institutes of Health 3
... The University of Wisconsin-Madison was one of seven U.S. ... Advanced Computing Center on Monday at the SC2004 high-power ... grant was the team led by Barton Miller , ... given to Miller and his team for their work on ...
... new book The Art of the Start: The ... Kawasaki, a managing director of Garage Technology Ventures, tells ... most entrepreneurs would be better off spending their time ... , ,This is a good message, but the delivery ...
... is over. Discounting some mutterings on the Internet, it appears ... the outcome, but rather of the process. , ,Yes, we ... and where we should be headed as a country. Yes, ... optimal integrity during the campaigning. Certainly it will take us ...
Cached Biology Technology:Scalable performance monitoring software draws grant from Intel 2Sarcasm and rainmaking advice coexist in The Art of the Start 2Sarcasm and rainmaking advice coexist in The Art of the Start 3Sarcasm and rainmaking advice coexist in The Art of the Start 4Sarcasm and rainmaking advice coexist in The Art of the Start 5Technology and democracy 2Technology and democracy 3
Monocarboxylate (lactate) transporter 2...
Chicken Anti-Human Stomatin-like 2 (STOML2 Polyclonal AntibodyNew Applications: ELISA, Western Blot...
MagSi monodispers, magnetic silica particles with modified surface for SO3 coupling chemistry....
Anti-Chicken IgY, (IgG) F(ab')2 Fragment Specific....
Biology Products: