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The influence of estrogen on female mood changes
Date:1/21/2012

This release is also available in Chinese on EurekAlert! Chinese.

Women's emotional responses can vary significantly premenstrually. They may become depressed or grumpy during menstruation or the premenstrual phase, known as premenstrual syndrome (PMS). Roughly 75% of reproductive-age women report premenstrual mood swings or physical discomfort. Brain scans show a significant increase in activity in the medial orbitofrontal cortex related to emotional processing premenstrually, even if women's emotional responses do not vary significantly. The relationship between estrogen and emotion was first investigated over 100 years ago, and it has been shown that estrogen can improve mood. Research has shown that during prepuberty, boys are twice as likely as girls to need psychotherapy. However, the opposite is true postpubertally. Women are twice as likely to develop anxiety or depressive disorders compared to men. Women's increased vulnerability to depressive disorders typically occurs between the beginning of puberty and the age of 55, in concert with estrogen level changes. In addition, it is believed that about 95% of women have recurrent psychosis or a noticeable increase in negative emotions along with the fluctuation in endogenous estrogen level. Therefore, understanding the relationship between estrogen level changes and cyclical mood disorders can provide a theoretical basis for improving female physical and mental health.

In their paper titled "Estrogen Impacts on Emotion: Psychological, Neuroscience and Endocrine Studies", Professor Luo Yue-Jia from the College of Brain and Cognitive Sciences of Beijing Normal University and Dr. Chen Chunping from the Institute of Psychology of the Chinese Academy of Sciences systematically reviewed research in the fields of neuroscience, psy
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Contact: Luo Yue-Jia
luoyj@bnu.edu.cn
Science in China Press
Source:Eurekalert

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