Navigation Links
The genome sequence of Tibetan antelope sheds new light on high-altitude adaptation
Date:5/17/2013

May 17, 2013, Shenzhen, China---- Why Tibetan antelope can live at elevations of 4,000-5,000m on the Qinghai-Tibetan Plateau? In a collaborative research published in Nature Communications, investigators from Qinghai University, BGI, and other institutes provide evidence that some genetic factors may be associated with the species' adaption to harsh highland environments. The data in this work will also provide implications for studying specific genetic mechanisms and the biology of other ruminant species.

The Tibetan antelope (Pantholops hodgsonii) is a native of the high mountain steppes and semi-desert areas of the Tibetan plateau. Interestingly, it is the only member of the genus Pantholops. Tibetan antelope is a medium sized antelope with the unique adaptations to against the harsh high-altitude climate. For non-native mammals such as humans, they may experience life-threatening acute mountain sickness when visiting high-altitude regions.

In this study, researchers suggest that Tibetan antelopes must have evolved exceptional mechanisms to adapt to this extremely inhospitable habitat. Using next-gen sequencing technology, they have decoded the genome of Tibetan antelope and studied the underlying genetic mechanism of high-altitude adaptations.

Through the comparison between Tibetan antelope and other plain-dwelling mammals, researchers found the Tibetan antelope had the signals of adaptive evolution and gene-family expansion in genes associated with energy metabolism and oxygen transmission, indicating that gene categories involved in energy metabolism appear to have an important role for Tibetan antelope via efficiently providing energy in conditions of low partial pressure of oxygen (PO2).

Further research revealed that both the Tibetan antelope and the highland American pika have signals of positive selection for genes involved in DNA repair and the production of ATPase. Considering the exposure
'/>"/>

Contact: Jia Liu
liujia@genomics.cn
BGI Shenzhen
Source:Eurekalert

Page: 1 2

Related biology news :

1. The DOE Joint Genome Institute expands capabilities via new partnerships
2. Scientists sequence genome of sacred lotus, which likely holds anti-aging secrets
3. Saving the parrots: Texas A&M team sequences genome of endangered macaw birds
4. Mapping the embryonic epigenome
5. Genome sequencing provides unprecedented insight into causes of pneumococcal disease
6. A new cost-effective genome assembly process
7. Turtle genome analysis sheds light on the development and evolution of turtle-specific body plan
8. CNIO researchers capture the replication of the human genome for the first time
9. Saint Louis University, University of Toronto biologists help decode turtle genome
10. Genome study suggests new strategies for understanding and treating pulmonary fibrosis
11. Coelacanth genome surfaces
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... published in the September issue of The ... novel strategy to diagnose the leading cause of ... damage has occurred. This advance involves quantifying the ... endothelium of retinal vessels. Using new probes developed ... early molecular development of diabetic retinopathy. , "My ...
(Date:9/2/2014)... perching birds, that migrate by night tend to fly ... reach their destinations. This seasonal difference in flight speed ... migratory flights, says researcher Cecilia Nilsson of Lund University ... Sociobiology . , Nilsson, in a group led ... measure over three years the speed by which birds ...
(Date:9/2/2014)... A study published in the September 2014 issue ... of Child and Adolescent Psychiatry found that ... had an increased risk of developing diabetes if ... from the nationwide Danish registers, a group of ... Aalborg University Hospital, Denmark, studied 48,299children and adolescents ...
Breaking Biology News(10 mins):Molecular probes permit doctors to detect diabetic retinopathy before vision fails 2Migrating birds sprint in spring, but take things easy in autumn 2Risk of diabetes in children and adolescents exposed to antipsychotics 2
... A new study led by York University researchers finds ... marked decrease in performance as a result of their blood ... of Pediatrics, reports that participants, athletic prowess was sapped by ... abilities also declined as a result. "Physical activity ...
... that optical microscopy can,t be used to "see" something ... is wont, clever science has once again overturned conventional ... of the Lawrence Berkeley National Laboratory (Berkeley Lab) Steven ... the use of optical microscopy to ,image objects or ...
... Prostate cancer is the second leading cause of ... cases diagnosed in the US in 2009 (Jemal 2009). ... risk factors for inflammation and prostate diseases including benign ... Sanjay Gupta, MS, PhD, Carter Kissell associate professor & ...
Cached Biology News:Diabetes shouldn't deter young athletes: York U study 2Diabetes shouldn't deter young athletes: York U study 3Correcting a trick of the light brings molecules into view 2Correcting a trick of the light brings molecules into view 3Correcting a trick of the light brings molecules into view 4Mechanism for link between high fat diet and risk of prostate cancer and disorders unveiled 2
(Date:9/2/2014)... NEW PROVIDENCE, N.J. , Sept. 2, ... a corporate sponsor for MassBio,s 20th Annual Golf Classic, ... MassBioEd Foundation. The event will be held on September ... Plymouth, Massachusetts . The ... Massachusetts through educational programs, workforce development, ...
(Date:9/2/2014)... Press attending the Project LIBERTY Grand Opening have ... people and events in Emmetsburg on Sept. 3. The ... day. Additionally, we will do our best to help ... well as representatives from the local community. Any advance ... remember to RSVP to Matt Merritt (matt.merritt@poetdsm.com) to receive ...
(Date:9/2/2014)... Opertech Bio, Inc., a company that ... approach to sensory evaluation, today announced the issuance ... Patent and Trademark Office, encompassing high-throughput sensory discrimination ... taste evaluation technology called Microtiter Operant Gustometer or ... for rapid characterization of taste sensory properties,” said ...
(Date:9/2/2014)... 2, 2014 /PRNewswire/ - BIOREM Inc. (TSXV: BRM) ("Biorem" or "the ... orders consist of three large odour control systems for waste ... "These orders are consistent with the market resurgence in ... , President and CEO. "After a difficult period of restraint ... beginning to see sales growth. Our lower cost structure, technology ...
Breaking Biology Technology:Linde helps fund STEM education in Massachusetts 2Linde helps fund STEM education in Massachusetts 3Press agenda for Project LIBERTY Grand Opening 2Press agenda for Project LIBERTY Grand Opening 3Press agenda for Project LIBERTY Grand Opening 4Press agenda for Project LIBERTY Grand Opening 5Opertech Bio Receives U.S. Patent for High-Throughput Taste Evaluation Technology 2
...  Aug. 23, 2011 Reliv International , Inc. ... Science Center today announced a new joint research and ... the latest soy and plant biotechnology research. ... some of the nation,s leading biotech researchers to develop ...
... MedNet Solutions, a global life sciences technology solutions company ... that MedNet has once again been recognized by Inc. ... in the United States.  MedNet is greatly honored to be ... since, as noted by Inc . magazine, "this prestigious ...
... YORK, Aug. 23, 2011 Reportlinker.com ... report is available in its catalogue: ... Microarrays, Lab-on-Chip, Protein Microarrays, Tissue & ... (2010-2015) http://www.reportlinker.com/p0595074/Biochips-Market-DNA-Microarrays-Lab-on-Chip-Protein-Microarrays-Tissue--Cell-Arrays-Trends--Global-Forecast-2010-2015.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Genomics ...
Cached Biology Technology:New Partnership Bolsters Reliv's Access to Plant Biotech Research 2New Partnership Bolsters Reliv's Access to Plant Biotech Research 3MedNet Solutions Achieves the Inc. 5000 List Five Years in a Row 2Biochips Market (DNA Microarrays, Lab-on-Chip, Protein Microarrays, Tissue & Cell Arrays) Trends & Global Forecast (2010-2015) 2Biochips Market (DNA Microarrays, Lab-on-Chip, Protein Microarrays, Tissue & Cell Arrays) Trends & Global Forecast (2010-2015) 3Biochips Market (DNA Microarrays, Lab-on-Chip, Protein Microarrays, Tissue & Cell Arrays) Trends & Global Forecast (2010-2015) 4Biochips Market (DNA Microarrays, Lab-on-Chip, Protein Microarrays, Tissue & Cell Arrays) Trends & Global Forecast (2010-2015) 5Biochips Market (DNA Microarrays, Lab-on-Chip, Protein Microarrays, Tissue & Cell Arrays) Trends & Global Forecast (2010-2015) 6Biochips Market (DNA Microarrays, Lab-on-Chip, Protein Microarrays, Tissue & Cell Arrays) Trends & Global Forecast (2010-2015) 7Biochips Market (DNA Microarrays, Lab-on-Chip, Protein Microarrays, Tissue & Cell Arrays) Trends & Global Forecast (2010-2015) 8Biochips Market (DNA Microarrays, Lab-on-Chip, Protein Microarrays, Tissue & Cell Arrays) Trends & Global Forecast (2010-2015) 9Biochips Market (DNA Microarrays, Lab-on-Chip, Protein Microarrays, Tissue & Cell Arrays) Trends & Global Forecast (2010-2015) 10Biochips Market (DNA Microarrays, Lab-on-Chip, Protein Microarrays, Tissue & Cell Arrays) Trends & Global Forecast (2010-2015) 11Biochips Market (DNA Microarrays, Lab-on-Chip, Protein Microarrays, Tissue & Cell Arrays) Trends & Global Forecast (2010-2015) 12Biochips Market (DNA Microarrays, Lab-on-Chip, Protein Microarrays, Tissue & Cell Arrays) Trends & Global Forecast (2010-2015) 13
UGT1A6 (D-20)...
... the Lone Wolf valve has the highest ... valve available on the market. This VSO ... performance, and ensures maximum accuracy., Achieves ... control and patient comfort. , Maintains ideal ...
Normal Hamster Serum...
...
Biology Products: