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The genetic heart of the lipids
Date:12/7/2008

ped using the new genetic variants are better at identifying those at risk of increased lipid levels, but do not yet improve the prediction of artery or heart disease.

Screening for a person with high lipid levels and early treatment with statins is one of the major strategies in the prevention of cardiovascular risk in clinical practice while a healthy diet, weight control and physical activity is the major population level prevention strategy.

"We can be confident that the increased understanding of the control of lipid levels that will come from these genetic discoveries, will, in time, lead to improved ways of treating and preventing heart disease and stroke" explains Mark McCarthy, Robert Turner Professor of Diabetes at the University of Oxford. "In addition, as we become better at identifying those individuals who are at most at risk of these diseases, we should be able to target our therapeutic and preventative efforts more efficiently, perhaps focusing on changing lifestyles in those most likely to benefit".


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Contact: Don Powell
don@sanger.ac.uk
44-012-234-96928
Wellcome Trust Sanger Institute
Source:Eurekalert

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