Navigation Links
The first caffeine-'addicted' bacteria
Date:3/27/2013

Some people may joke about living on caffeine, but scientists now have genetically engineered E. coli bacteria to do that literally. Their report in the journal ACS Synthetic Biology describes bacteria being "addicted" to caffeine in a way that promises practical uses ranging from decontamination of wastewater to bioproduction of medications for asthma.

Jeffrey E. Barrick and colleagues note that caffeine and related chemical compounds have become important water pollutants due to widespread use in coffee, soda pop, tea, energy drinks, chocolate and certain medications. These include prescription drugs for asthma and other lung diseases. The scientists knew that a natural soil bacterium, Pseudomonas putida CBB5, can actually live solely on caffeine and could be used to clean up such environmental contamination. So they set out to transfer genetic gear for metabolizing, or breaking down, caffeine from P. putida into that old workhorse of biotechnology, E. coli, which is easy to handle and grow.

The study reports their success in doing so, as well as use of the E. coli for decaffeination and measuring the caffeine content of beverages. It describes development of a synthetic packet of genes for breaking down caffeine and related compounds that can be moved easily to other microbes. When engineered into certain E. coli, the result was bacteria literally addicted to caffeine. The genetic packet could have applications beyond environmental remediation, the scientists say, citing potential use as a sensor to measure caffeine levels in beverages, in recovery of nutrient-rich byproducts of coffee processing and for the cost-effective bioproduction of medicines.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Ludwig cancer researchers honored among first class of fellows in AACR Academy
2. Discovery of first motor with revolution motion in a virus-killing bacteria advances nanotechnology
3. Antarcticas first whale skeleton found with 9 new deep-sea species
4. Antarcticas first whale skeleton found with nine new deep-sea species
5. Series of studies first to examine acupunctures mechanisms of action
6. Researchers explain a key developmental mechanism for the first time in plants
7. Age at first menstrual cycle, menopause tied to heart disease risk
8. Genetic signs of alcoholism in women studied for the first time
9. Synthetic molecule first electricity-making catalyst to use iron to split hydrogen gas
10. Spectacular forcepfly species discovered for the first time in South America
11. World first for fly research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... the human genome was unveiled today in the form ... yet of how the genomes of the fruit fly, ... August 28 in in the journal Nature , ... genomes is "read out," and how their DNA and ... billions of entries to a publicly available archive of ...
(Date:8/27/2014)... University researchers have identified a gene that could help ... a protein in the cell membrane of plants that ... water conservation machinery accordingly. , "It,s similar to ... biology at Duke. , The findings, which appear ... make it easier to feed the world,s growing population ...
(Date:8/27/2014)... when it only requires nerve cells to rearrange existing ... to generate new patterns, a study of monkeys has ... through recordings of electrical activity of brain cell networks. ... of Health. , "We looked into the brain and ... outside the box," said Aaron Batista, Ph.D., an assistant ...
Breaking Biology News(10 mins):Encyclopedia of how genomes function gets much bigger 2Encyclopedia of how genomes function gets much bigger 3Encyclopedia of how genomes function gets much bigger 4Water 'thermostat' could help engineer drought-resistant crops 2Scientists plug into a learning brain 2Scientists plug into a learning brain 3
... countless coral reefs around the world can now be nabbed ... say. Coral researchers and reef managers will be able ... them to classify specific diseases based on the presence of ... reduce the impact of disease on the world,s imperilled coral ...
... Alto, CA--The four largest nonprofit plant science research institutions ... Association of Independent Plant Research Institutes (AIPI) in an ... profound challenges facing society in a more coordinated and ... Thompson Institute for Plant Research (Cornell University), The Carnegie ...
... for athletes looking to boost performance comes in the form ... reason for its popularity is twofold says Scott Forbes, a ... precursor for nitric oxide that is known to improve blood ... nutrients to working muscles and assist with metabolic waste product ...
Cached Biology News:Scientific sleuths pinpoint the guilty coral killers 2Big boost to plant research 2Big boost to plant research 3L-arginine: Supplement tested on fit, athletic men shows no advantage 2L-arginine: Supplement tested on fit, athletic men shows no advantage 3
(Date:8/26/2014)... An analysis by Replikins, Ltd. of Pubmed data of ... virus strains has revealed extensive conservation and sharing of ... sharing of specific Replikin gene structures has permitted the ... did for the H5N1 influenza vaccine and the Taura ... to be effective (1,2). This ...
(Date:8/26/2014)... team of engineers from Singapore has successfully piloted ... for satellite communications. , With the weight of ... constructing a lightweight, low power-consuming, wireless communication system ... has always been a challenge for system designers. ... Centre of Nanyang Technological University in Singapore launched ...
(Date:8/26/2014)... MINNEAPOLIS and REHOVOT, Israel , ... UK medical 3D printing specialist, Replica 3DM, supports NHS hospitals ... 3D Printers   - Performing surgery ... and anesthetic times; improves patient recovery and provides an effective ... Stratasys Ltd. (Nasdaq: SSYS ), a ...
(Date:8/26/2014)... , Aug. 26, 2014  ViveBio, LLC a ... collection, stabilization and transportation, announced today that it ... Services, LLC (LPS) of Knoxville, Tennessee ... in the United States . ... of ambient temperature dried biological specimen transport systems.  ...
Breaking Biology Technology:ZigBee in the Sky 2Twelve UK Hospitals Enjoy Reduced Surgical Procedure Times and Decline in Costs by Implementing Stratasys 3D Printing Solutions 2Twelve UK Hospitals Enjoy Reduced Surgical Procedure Times and Decline in Costs by Implementing Stratasys 3D Printing Solutions 3Twelve UK Hospitals Enjoy Reduced Surgical Procedure Times and Decline in Costs by Implementing Stratasys 3D Printing Solutions 4Twelve UK Hospitals Enjoy Reduced Surgical Procedure Times and Decline in Costs by Implementing Stratasys 3D Printing Solutions 5ViveBio and Laboratory Procurement Services Sign Agreement for Distribution of the ViveST Line of Products 2
... XTL,Biopharmaceuticals Ltd. (Nasdaq: XTLB ; TASE: XTL) today ... XTL,s Board of Directors.,The appointment, effective immediately, increases the ... 61, recently retired from his position as a Partner ... and,advisory services firm, having served that firm for over ...
... Today sees the launch of a new collaborative website ... and medicine. The WikiProfessional technology underlying the site has ... in BioMed Centrals open access journal Genome Biology, WikiProteins ... scale. , The article is written by Barend ...
... Researchers at North Carolina State University have created a ... which retains these properties under extremely high temperatures ... applications, such as engine components that are exposed to ... is made up of nanoscale crystals is far stronger ...
Cached Biology Technology:XTL Biopharmaceuticals Announces Appointment of Laurence N. Charney to Board of Directors 2XTL Biopharmaceuticals Announces Appointment of Laurence N. Charney to Board of Directors 3Large-scale community protein annotation -- WikiProteins 2
... fast and specific detection of chromosomal sequences ... hybridisation time ( Works ... Multiplex capability Available with different tags ... available with different labels. Related Content: ...
... rat adult and fetal tissue, ... * T75 plated cells $750.00, ... This product requires Celprogen Stem ... and extracellular matrix, * E55007-08-T25 ...
... Bacterial DNA Isolation Kit provides a rapid ... genomic DNA from the various bacterial species ... the isolation of genomic DNA from both ... milk samples. ,Purification is based on ...
...
Biology Products: