Navigation Links
The endocannabinoids: Functional roles and therapeutic opportunities
Date:10/14/2007

eptors or possibly also by antagonists to the CB1 receptors may have therapeutic potential. The endocannabinoid system generally is involved in the protective reaction of the mammalian body to a long list of neurological diseases such as multiple sclerosis, Alzheimer's and Parkinson's disease. Thus, there is hope for novel therapeutic opportunities.

Numerous additional endocannabinoids especially various fatty acid ethanolamides and glycerol esters are known today and regarded as members of a large endocannabinoid family. Endogenous cannabinoids, the cannabinoid receptors and various enzymes that are involved in their syntheses and degradations comprise the endocannabinoid system.

The endocannabinoid system acts as a guardian against various attacks on the mammalian body.

Conclusion

The above described research concerning the endocannabinoid-system is of importance in both basic science and in therapeutics:

  • The discovery of the cannabis plant active constituent has helped advance our understanding of cannabis use and its effects.

  • The discovery of the endocannabinoids has been of central importance in establishing the existence of a new biochemical system and its physiological roles in particular in neuroprotection.

  • These discoveries have opened the door for the development of novel types of drugs, such as THC for the treatment of nausea and for enhancing appetite in cachectic patients.

  • The endocannabinoid system is involved in the protective reaction of the mammalian body to a long list of neurological diseases such as multiple sclerosis, Alzheimer's and Parkinson's disease which raises hope for novel therapeutic opportunities for these diseases.


'/>"/>

Contact: Professor Raphael Mechoulam
mechou@cc.huji.ac.il
European College of Neuropsychopharmacology
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Towards precise classification of cancers based on robust gene functional expression profiles
2. Software Tool for Converting Scientific Text into a Database of Functional Relationships
3. Physical and functional interaction of key cell growth molecules linked to cancer
4. Bone marrow cells can become functional gut lining cells
5. Conserved amino acids play both structural and mechanistic roles in sandwich-like protein
6. Flies on speed offer insight into the roles of dopamine in sleep and arousal
7. Bedsores and bald hides: Novel roles revealed for a scaffolding protein
8. New roles for growth factors: Enticing nerve cells to muscles
9. Master planners in brain may coordinate other areas roles in cognitive tasks
10. Sunflower speciation highlights roles for transposable elements in evolution
11. Study reveals candidate targets for anti-retroviral therapeutics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... Sept. 18, 2014 -- Arizona turned its newborn screening program ... few short months, earning it the first-ever Newborn Screening Quality ... of Dimes presented Will Humble, M.P.H., Arizona,s Department of Health ... today. Mr. Humble established a policy of full transparency for ... newborn blood samples to the lab for analysis, and set ...
(Date:9/18/2014)... carbon and nitrogen comprise all spheres of our ... have caused imbalances and perturbations that resulted in ... GHGs result in climate changes which influence the ... the atmosphere. Understanding these feedback mechanisms has become ... science during the past three decades. , In ...
(Date:9/18/2014)... up to 400 kilometres in search of a home, which ... Clownfish spend their entire adult lives under the protection of ... open ocean, says study co-author, Dr Hugo Harrison from the ... at James Cook University. , "In the past we haven,t ... rare glimpse into how far they can swim, crossing large ...
Breaking Biology News(10 mins):March of Dimes honors Arizona with first-ever newborn screening award 2March of Dimes honors Arizona with first-ever newborn screening award 3Greenhouse gas research enters a new era 2Nemo's epic journey to find a new home 2
... species (ROS), or 'oxygen radicals', have been identified as ... prevalence linked to inflammation-associated syndromes and a variety of ... San Diego Branch of the Ludwig Institute for Cancer ... repair and cell cycle control genes in yeast that ...
... in winter and spring snow cover over Southwest Asia and ... blooms of ocean plants in the Arabian Sea. , The ... both temperature and pressure systems between the Indian subcontinent and ... mix the ocean water in the Western Arabian Sea. This ...
... benefit from treatment with mixtures of customized antibodies. In ... National Academy of Sciences (USA), a team of Weizmann ... form a web that destroys the cancer cell's communication ... intensive cancer research led to the identification of a ...
Cached Biology News:Yeast Network Prevents Damage By Oxygen Radicals 2NASA study finds snow melt causes large ocean plant blooms 2Two are better than one 2
(Date:9/19/2014)...  An entire month is dedicated to one of ... disease (CMT) – a debilitating neuromuscular disease affecting the ... weakness, and foot and hand deformities. CMT affects 1 ... is a progressive disease, and over time patients lose ... such as leg braces, wheelchairs and scooters to get ...
(Date:9/19/2014)... , September 19, 2014 ... latest developments, patents and results of studies and trials. ... Lilly and Company (NYSE: LLY ), Gilead ... (NASDAQ: CELG ) and Arena Pharmaceuticals Inc. ... leader in developing prodrug therapeutics for the treatment of ...
(Date:9/19/2014)... 2014 , The first grants ... Paediatric Endocrinology (ESPE) Meeting  Investment supports innovative ... in the field of growth  , EMD ... Germany , today announced the first recipients of ... awards were announced during a Satellite Symposium organized by ...
(Date:9/18/2014)... , Sept. 18, 2014 About ... testing, is performed outside a clinical laboratory. It ... in administrating appropriate treatments and medication. POCT is ... prevalence of lifestyle diseases such as diabetes, heart ... user-friendly. POCT devices are standardized to minimize errors ...
Breaking Biology Technology:September is Charcot-Marie-Tooth (CMT) Awareness Month - Scheduled events, activities and important partnerships announced throughout the month! 2Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 2Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 3Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 4Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 5Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 6Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 7EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 2EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 3POCT Market in China 2014-2018 2
... , , , Kurt Lucas, Eppendorf AG , ... , Significance of cell fusion , ... methods in modern biology, such as the production of monoclonal ... Compared to the , chemically induced cell fusion via polyethylene ...
... , , , , , , , ... procedure.(1,2,3), The basic protocol given here works with E. coli cultures grown ... LB or DYT, or in 250 , ml Terrific Broth. , ... Pellet bacteria from the culture at 10,000 x g for 5 minutes at room , ...
... , , , , , , ... Eppendorf 5 Prime, Inc. , , , , ... It is not convenient in all instances to have blood drawn for gDNA extraction. , ... gDNA from , saliva with only slight modifications to the ...
Cached Biology Technology:Principles and applications of electrical cell fusion 2Principles and applications of electrical cell fusion 3Principles and applications of electrical cell fusion 4Principles and applications of electrical cell fusion 5Basic Plasmid DNA Isolation Protocol 2Isolation of Genomic DNA from Saliva Using the Perfect gDNA Blood Mini , Kit 2Isolation of Genomic DNA from Saliva Using the Perfect gDNA Blood Mini , Kit 3Isolation of Genomic DNA from Saliva Using the Perfect gDNA Blood Mini , Kit 4Isolation of Genomic DNA from Saliva Using the Perfect gDNA Blood Mini , Kit 5Isolation of Genomic DNA from Saliva Using the Perfect gDNA Blood Mini , Kit 6
... The EC570-90 is a compact, lightweight, high ... 500 volts or 2500 milliamps. It is an ... RNA submarine gels. It is also ideal for ... time can be set to automatically end a ...
Rat Hepatocytes (RH) (>3,000,000 cells)...
QCPN...
Rat Aortic Smooth Muscle Cells (RAOSMC) (>500,000 cells)...
Biology Products: