Navigation Links
The dark path to antisocial personality disorder
Date:2/7/2012

Philadelphia, PA, February 7, 2012 With no lab tests to guide the clinician, psychiatric diagnostics is challenging and controversial. Antisocial personality disorder is defined as "a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood," according to the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) of the American Psychiatric Association.

DSM-IV provides formal diagnostic criteria for every psychiatric disorder. This process may be guided by rating scales that measure the traits and features associated with a personality disorder. But, until now, no one has studied the dimensional structure associated with the DSM antisocial personality disorder criteria.

Dr. Kenneth Kendler of Virginia Commonwealth University and colleagues examined questionnaire and genetic data from adult twins. They found that the DSM-IV criteria do not reflect a single dimension of liability but rather are influenced by two dimensions of genetic risk reflecting aggressive-disregard and disinhibition.

"When psychiatrists, as clinicians or researchers, think about our psychiatric disorders, we tend to think of them as one thing one kind of disorder a reflection of one underlying dimension of liability," said Dr. Kendler. "This is also true of genetics researchers. We tend to want to identify and then detect 'the' risk genes underlying disorder X or Y."

Kendler added, "What is most interesting about the results of this paper is that they falsify this inherent and rather deeply held assumption. Genetic risk factors for antisocial personality disorder are not one thing. Rather, the disorder, as conceptualized by DSM-IV, reflects two distinct genetic dimensions of risk."

"The findings from this study make sense. The distinction between the two sets of heritable traits contributing to antisocial personality diso
'/>"/>

Contact: Rhiannon Bugno
Biol.Psych@utsouthwestern.edu
214-648-0880
Elsevier
Source:Eurekalert

Page: 1 2

Related biology news :

1. Biography captures Sydney Brenners unflagging scientific curiosity and lively personality
2. Personality predicts political preferences
3. Understanding a cells split personality aids synthetic circuits
4. Cells split personality is a major discovery into neurological diseases
5. Sugar, spice and puppy dog tails: Developing sex-typed personality traits and interests
6. MU researcher identifies possible genetic causes of borderline personality disorder
7. New test spots early signs of inherited metabolic disorders
8. Severe congenital disorder successfully treated in a mouse model for the first time
9. Controlled disorder -- scientists find way to form random molecular patterns
10. Picower: Schizophrenia gene associated with psychiatric disorders and brain development
11. Diagnoses of autism spectrum disorders vary widely across clinics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2015)... 2015 The wearable technology market has ... and healthy. However, wearable technology has the potential ... help improve diagnostic capabilities and therapeutic outcomes. Today, ... Wearable Technologies Conference 2015 , where Barrett ... in healthcare.    "Over the past ...
(Date:8/18/2015)... , Aug. 17, 2015 Research ... addition of the "Global Biometric Authentication & ... - Estimation & Forecast, 2015-2020" report to ... authentication and identification systems market is expected to ... 2015 to 2020 and generate over $25 billion ...
(Date:8/12/2015)... , Aug. 12, 2015  Synaptics Inc. (NASDAQ: ... interface solutions, today announced that four of its ... solution, have officially been named FIDO Certified™ by ... of the certification, Synaptics, Natural ID™ fingerprint solutions ... Authentication Framework (UAF) standard and are interoperable among ...
Breaking Biology News(10 mins):Leaf Healthcare Releases Video from Wearable Technology Conference on New Applications for Wearables in the Hospital Environment 2Leaf Healthcare Releases Video from Wearable Technology Conference on New Applications for Wearables in the Hospital Environment 3Global Biometric Authentication & Identification Market 2015: Focus On Modality, Motility & Application - Estimation & Forecasts to 2020 for the $25 Billion Industry 2Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 2Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 3
... a 19th-century British artist and naturalist who significantly changed ... pre-human inhabitants. Hawkins drew worldwide attention in 1868 when ... Hadrosaurus foulkii , at The Academy of Natural ... remount a cast of Hadrosaurus in November, the Academy ...
... 50% of crop sales in the United States, and ... But more information is needed about the crops, growth ... management practices such as irrigation can be precisely scheduled. ... variations in crops, planting densities, and cultural practices. ...
... 2008) The U.S. Environmental Protection Agency has released a ... on human health, human welfare, and communities in the ... Global Change on Human Health and Welfare and Human ... the challenges of a changing climate and identifies near- ...
Cached Biology News:Academy publishes first biography of artist-naturalist Benjamin Waterhouse Hawkins 2Academy publishes first biography of artist-naturalist Benjamin Waterhouse Hawkins 3Digital cameras, remote satellites measure crop water demand 2
(Date:9/1/2015)... ... 01, 2015 , ... A new host-based therapy for Ebola, ... Keck Graduate Institute and its collaborators. The discovery has the potential to speed ... on August 27 by Scientific Reports, an open access research journal from the ...
(Date:8/31/2015)... ... August 31, 2015 , ... ... bring together supply chain risk management and resiliency practitioners with luminaries and thought ... best practices, and be recognized for their innovations and performance excellence. At that ...
(Date:8/31/2015)... 31, 2015 Research and Markets ( http://www.researchandmarkets.com/research/v7fdpx/argentina ... Biomedical Sensors Market - Growth, Trends & Forecasts (2014-2020)" ... Argentina Biomedical Sensors market is estimated at $0.17 billion ... period 2014-2020 The near future will bring ... of each individual. These sensors can be set to ...
(Date:8/31/2015)...  For people with Down syndrome, news from ... company, located in the Science + Technology Park at ... therapies yet for people with Down syndrome and other chromosome ... syndrome and Edwards syndrome aneuploidies in human cell cultures, ... Elixirgen plans to develop this technology into a treatment ...
Breaking Biology Technology:Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax 2Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax 3Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax 4Global Supply Chain Resiliency Council Announces Incorporation and Web Site Launch 2Global Supply Chain Resiliency Council Announces Incorporation and Web Site Launch 3Argentina Biomedical Sensors Market Report 2015 - Growth, Trends & Forecasts 2014-2020 2New Down syndrome therapy discovered 2
... Genomic DNA Tissue Kit , Catalog #732-6343, ... Sample De-paraffinization , 1. Place 510 mg (0.0050.010 g) ... l xylene and incubate 5 min with constant mixing at room , temperature. ... , Discard the xylene. , 3. Repeat ...
... 2 E. Lehmann, 2 L. Hennes, 3 , ... 1 Department of Biological Anthropology, University of Cambridge,U.K. , ... , ... Hospital and Clinics, Madison, Wisconsin, U.S.A. , Introduction ...
... by Philip W Miller, Waltraud I Dunn, and Robert R Schmidt, , ... FL 32611 USA , ... , Introduction , ... the pre- , and posttranslational mechanisms that regulate both ...
Cached Biology Technology:DNA Isolation From 50 to 20 mg of Paraffin-Embedded Tissue 2Separation of HLA-DRB Alleles by Denaturing Gradient Gel Electrophoresis using the DCode System 2Separation of HLA-DRB Alleles by Denaturing Gradient Gel Electrophoresis using the DCode System 3Separation of HLA-DRB Alleles by Denaturing Gradient Gel Electrophoresis using the DCode System 4Preparative Nondenaturing Gel Electrophoresis to Purify NADP-Specific Glutamate Dehydrogenase From Chlorella, Rev B 2Preparative Nondenaturing Gel Electrophoresis to Purify NADP-Specific Glutamate Dehydrogenase From Chlorella, Rev B 3Preparative Nondenaturing Gel Electrophoresis to Purify NADP-Specific Glutamate Dehydrogenase From Chlorella, Rev B 4Preparative Nondenaturing Gel Electrophoresis to Purify NADP-Specific Glutamate Dehydrogenase From Chlorella, Rev B 5Preparative Nondenaturing Gel Electrophoresis to Purify NADP-Specific Glutamate Dehydrogenase From Chlorella, Rev B 6
Alexa Fluor 647 anti-mouse Qa-2...
... essential for hunting and analyzing the ... as EST sequencing projects, microarrays, functional ... is developed for normalization of cDNA ... for directional cloning. While most normalization ...
... acquision and analysis software for ... applications. Contains powerful stimulus generation ... functions including automated waveform feature ... includes many electrophysiology specific functions ...
normal human fibroblasts Source: Cell Lysate Form: Ready to Use Application: Western Blotting Control...
Biology Products: