Navigation Links
The brain knows what the nose smells, but how? Stanford researchers trace the answer
Date:2/4/2011

Mice know fear. And they know to fear the scent of a predator. But how do their brains quickly figure out with a sniff that a cat is nearby?

It's a complex process that starts with the scent being picked up by specific receptors in their noses. But until now it wasn't clear exactly how these scent signals proceeded from nose to noggin for neural processing.

In a study to be published in Nature (available online now to subscribers), Stanford researchers describe a new technique that makes it possible to map long-distance nerve connections in the brain. The scientists used the technique to map for the first time the path that the scent signals take from the olfactory bulb, the part of the brain that first receives signals from odor receptors in the nose, to higher centers of the mouse brain where the processing is done.

"No one could trace signals across neural connections to a specific type of neuron at a specific location before," said biology Professor Liqun Luo. This is Luo's first study of the mouse olfactory system, but his lab has spent 10 years studying olfactory pathways in the fruit fly. Because mouse brains are so much larger and more complex that those of flies, Luo and postdoctoral researcher Kazunari Miyamichi had to develop an entirely new experimental technique.

These techniques can be used to do more than just study how mice smell. "The tools we've developed can be applied to trace neural connections of any part of the nervous system," Luo said. The tools could be used to understand how mouse brains process information from their other senses, or how the brain controls movement. The tools could also be adapted for use in rats and other mammalian species, he said.

To trace the neural pathways, the researchers injected mouse brains with two viruses, one after the other.

The researchers first injected a low-grade virus into the higher centers of a mouse brain, where it infected near
'/>"/>

Contact: Louis Bergeron
louisb3@stanford.edu
650-725-1944
Stanford University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Scientific research reveals brain alterations linking omega 3 deficit with depression
2. Neurobiologists find that weak electrical fields in the brain help neurons fire together
3. Early tests find nanoshell therapy effective against brain cancer
4. Brain can learn to overcome sleep apnea: U of T scientist
5. Learn more quickly by transcranial magnetic brain stimulation
6. Conversion of brain tumor cells into blood vessels thwarts treatment efforts
7. New molecule could save brain cells from neurodegeneration, stroke
8. Reducing diet early in pregnancy stunts fetal brain development
9. New technique to see neurons of the deep brain for months at a time developed at Stanford
10. LCD projector used to control brain and muscles of tiny organisms such as worms
11. Researchers show how Alzheimers plaques lead to loss of nitric oxide in brain
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
The brain knows what the nose smells, but how? Stanford researchers trace the answer
(Date:12/10/2014)... RALEIGH, N.C. , Dec. 9, 2014  Valencell, ... announced it is seeing a staggering demand from its ... demand, the Company revealed, is not solely coming from ... industries as well. "A wearable is only ... a result, accuracy is the ultimate driver in long-term ...
(Date:12/5/2014)... , Dec. 4, 2014 Increased emphasis ... investments in new testing and inspection technologies. The ... rise to a range of innovative test solutions. ... of Generation Y, which is generally more inclined ... result, product development strategies of test equipment vendors ...
(Date:11/21/2014)... , November 18, 2014 ... Systems Market by Systems (Video, RFID, Access Control, Intrusion ... Factories, Hotels, Banks, Government), Component Service Geography - Global ... Systems Market is projected to be around $25 Billion ... by 2020, growing at a CAGR of 8.69%. ...
Breaking Biology News(10 mins):Wearable Technology Products Demand Highly Accurate Biometric Technology 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3
... It seems the old nature versus nurture debate can,t be ... the Philippines makes a strong case for nurture,s role in ... in the first six months of life predicts earlier puberty ... babies -- an indication that they were not nutritionally stressed ...
... tread of a pesky fly landing on your face may strike ... small annoyances. But for scientists working to develop pressure sensors ... sensitive enough to feel the tickle of fly feet would be ... sensor. By sandwiching a precisely molded, highly elastic rubber ...
... Ariz. Arizona State University,s expanding research, education ... has led to formation of the Center for ... recently approved establishment of the center, which will ... engineering, physics, materials science and engineering, and bioengineering. ...
Cached Biology News:Male maturity shaped by early nutrition 2Male maturity shaped by early nutrition 3New artificial skin could make prosthetic limbs and robots more sensitive 2New artificial skin could make prosthetic limbs and robots more sensitive 3Focus on photonics 2
(Date:12/17/2014)... (PRWEB) December 17, 2014 Gene ... that it has entered into a technology access ... (ADM) to apply DNA2.0’s proprietary protein engineering technology, ... process. , “We are extremely excited that the ... platform. This proprietary bioengineering technology has now ...
(Date:12/17/2014)... SOUTH SAN FRANCISCO, Calif. , Dec. 17, ... positive results of a Phase 2 study evaluating ... for the treatment of patients with severe, chronic ... the current standard of care, including topical steroids ... endpoint was percent change in Visual Analog Scale ...
(Date:12/15/2014)...  GlassesOff Inc. (OTCBB: GLSO) announced today the appointment ... director of the Company,s Board of Directors. ... its CEO until its acquisition by Stanley Black ... Recognized as the inventor of the first Wi-Fi-based Active ... -based RFID solutions focused on improving operational efficiency, safety ...
(Date:12/13/2014)... (PRWEB) December 12, 2014 Clarassance, a ... announced its new name: Therabron Therapeutics , Inc. ... and bronchioles (a type of structure in the lungs ... company’s mission to develop novel protein therapeutics for the ... directors decided to change the name to mark the ...
Breaking Biology Technology:ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3Maryland-based Biotech Company's Path Forward in Treating Respiratory Diseases Sparks Name Change 2
... -- GE Healthcare's LightSpeed VCT, the world's ... today by the Wall Street Journal ... global Technology Innovation Awards. The annual awards recognize ... the world in a wide range of areas, ...
... bicycle industry by buying some of the most traditional, ... company has jumped full speed into the future with ... its systems. , ,The company, which owns such traditional ... names such as GT and Mongoose, finds itself on ...
... women entrepreneurs? , ,The market is good for their ... and the revenue from them has increased faster than the ... less likely to fail, too, experts say. , ,Finding money ... , ,The problem is not limited to Wisconsin, but is ...
Cached Biology Technology:Pacific Cycle rides full speed into RFID 2Pacific Cycle rides full speed into RFID 3Women and Capital: Two words that dont always marry 2Women and Capital: Two words that dont always marry 3Women and Capital: Two words that dont always marry 4
... Concept in Microarrays: Biomedical Photometrics Inc. (Waterloo, ... (Jena, Germany) have collaborated to develop a ... System. The DNAscope AT is based ... DNAscope AT automatically reads up to six ...
Complement factor B (human)...
Best pricing for 100mg-1.0g scales. Phosphopeptides are our specialty....
... 10 Capillary Electrophoresis Running Buffer was designed ... throughput demands of todays sequencing labs. As ... TBE to the gel-based sequencing community Sigma ... capacity to meet your buffer needs. Scientists ...
Biology Products: