Navigation Links
The aorta is torn apart in the Marfan syndrome
Date:7/17/2008

A severe complication of the Marfan syndrome is that the aorta may split and be torn apart. The patient can be protected if the syndrome is diagnosed and treated in good time. In the current edition of the Deutsches rzteblatt International (Dtsch Arztebl Int 2008; 105[27]: 483-91), the human geneticist Mine Arslan-Kirchner from Hannover University Medical School and his coauthors present additional studies on Marfan patients.

http://www.aerzteblatt.de/v4/archiv/pdf.asp?id=60813

Marfan syndrome occurs at a frequency of between 1:5000 and 1:10000 and is either hereditary or the result of spontaneous genetic mutations. As a consequence, there are changes in the consistency of connective tissue. Symptoms develop in the cardiovascular system, the eyes, and the skeleton. A much feared and potentially fatal complication is that the aorta can split and tear. The patient can then die from internal bleeding. Patients' average life expectancy is 32 years without treatment, but can be extended to 60 years with optimal therapy. The full-blown disease is not always present; individual symptoms may be lacking. This makes reliable diagnosis difficult and in many cases, clinical and molecular genetic studies must be combined to clarify the situation. If the diagnosis is made in good time, the damaged aorta can be surgically replaced.


'/>"/>

Contact: Elke Bartholomaeus
bartholomaeus@aerzteblatt.de
49-223-470-11133
Deutsches Aerzteblatt International
Source:Eurekalert

Page: 1

Related biology news :

1. After more than 100 years apart, webworms devastate New Zealand parsnips
2. Gene regulation, not just genes, is what sets humans apart
3. Researchers discover gene for branchio-oculo-facial syndrome
4. Study suggests new way to screen infants for fetal alcohol syndrome
5. Effective ADHD treatment found for children with fragile X syndrome
6. Rare cancer-causing syndrome found, for the first time, in Singapore
7. Obesity-related hormone is higher in children with Down syndrome
8. Restless legs syndrome affects nearly 2 percent of US/UK children
9. Researchers identify proteins involved in new neurodegenerative syndrome
10. Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/21/2016)... 21, 2016 NuData Security announced today that ... of principal product architect and that Jon ... customer development. Both will report directly to ... moves reflect NuData,s strategic growth in its product ... customer demand and customer focus values. ...
(Date:6/9/2016)... in attendance control systems is proud to announce the introduction of fingerprint attendance control ... right employees are actually signing in, and to even control the opening of doors. ... ... ... Photo - ...
(Date:6/2/2016)... The Department of Transport Management (DOTM) of ... project, for the , Supply and Delivery of ... Infrastructure , to Decatur , ... Management Solutions. Numerous renowned international vendors participated in the tendering ... selected for the most compliant and innovative solution. The contract ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... , ... June 23, 2016 , ... ... pleased to announce the launch of their brand, UP4™ Probiotics, into Target stores ... 35 years, is proud to add Target to its list of well-respected retailers. ...
(Date:6/23/2016)... 23, 2016 Houston Methodist Willowbrook Hospital ... Sports Association to serve as their official health ... Methodist Willowbrook will provide sponsorship support, athletic training ... association coaches, volunteers, athletes and families. ... Sports Association and to bring Houston Methodist quality ...
(Date:6/23/2016)... , June 23, 2016   EpiBiome , a ... $1 million in debt financing from Silicon Valley Bank ... automation and to advance its drug development efforts, as ... facility. "SVB has been an incredible strategic ... services a traditional bank would provide," said Dr. ...
(Date:6/23/2016)... 2016 Apellis Pharmaceuticals, Inc. today announced ... of its complement C3 inhibitor, APL-2. The trials ... dose studies designed to assess the safety, tolerability, ... in healthy adult volunteers. Forty subjects ... single dose (ranging from 45 to 1,440mg) or ...
Breaking Biology Technology: