Navigation Links
The Michael J. Fox Foundation awards nearly $200,000 to develop novel drugs for Parkinson's disease
Date:10/31/2011

The Michael J. Fox Foundation for Parkinson's Research (MJFF) has awarded a grant to Academy Professor Mart Saarma, PhD, and his team at the Institute of Biotechnology of the University of Helsinki. The funding will be used in conjunction with HermoPharma Company for the therapeutic development of the neurotrophic factor cerebral dopamine neurotrophic factor (CDNF) as a potential treatment for Parkinson's disease (PD).

Saarma's major breakthrough in this field was the discovery of CDNF, and he has performed subsequent demonstrations that it has potential to both protect and repair injured neurons in pre-clinical models of PD. MJFF has been funding Saarma's team to investigate CDNF since 2006, including a $500,000 award in 2010 to study the therapeutic potential of CDNF in pre-clinical models of PD. The newly-awarded grant will be used to further complete these studies.

PD is a disorder of the central nervous system that results from the loss of dopamine-producing brain cells. Neurotrophic factors are are proteins that promote the survival, growth and function of neurons in the brain, and therefore, are of major interest to PD researchers.

Saarma's team and a team headed by Professor Raimo K. Tuominen, MD, PhD, of the Faculty of Pharmacy, have in the past compared the neuroprotective and neurorestorative properties of CDNF with those of other neurotrophic factors like glial cell line-derived neurotrophic factor, or GDNF. The results were promising in terms of developing CDNF as a novel treatment for PD.

Future pre-clinical studies on the efficacy of CDNF on PD are being carried out in collaboration with Judy L. Cameron, PhD, of the University of Pittsburgh and with Zhiming Zhang, MD, of the University of Kentucky.


'/>"/>

Contact: Mart Saarma
mart.saarma@helsinki.fi
358-505-002-726
University of Helsinki
Source:Eurekalert

Page: 1

Related biology news :

1. LLNL selects Madhav Marathe for the first George A. Michael Distinguished Scholar Award
2. Dr. Michael Collins publishes paper on ivory-billed woodpecker
3. Michael S. Watson, Ph.D., receives Am College of Medical Genetics-ACMG Foundation Presidents Award
4. 2011 HFSP Nakasone Award for Michael Elowitz of Caltech
5. Michael Graetzel wins the Millennium Technology Prize
6. Adult Star Katie Michaels Attending NHL Game 7 Red Wings vs. Coyotes
7. Michael Betenbaugh wins 2010 Cell Culture Engineering award
8. American Society for Microbiology honors J. Michael Miller
9. Pacific Biometrics, Inc. Announces the Appointment of Michael Murphy, PhD as Chief Operating Officer
10. Annual Michael & Susan Dell lectureship in child health
11. National Science Foundation makes first awards in Sustainability Research Coordination Program
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2016)...   The Weather Company , an IBM Business (NYSE: ... capability in which consumers will be able to interact with ... via voice or text and receive relevant information about the ... Marketers have long sought an advertising solution that can create ... relevant and valuable; and can scale across millions of interactions ...
(Date:6/1/2016)... , June 1, 2016 Favorable ... Election Administration and Criminal Identification to Boost Global Biometrics ... recently released TechSci Research report, " Global Biometrics Market ... Competition Forecast and Opportunities, 2011 - 2021", the global ... by 2021, on account of growing security concerns across ...
(Date:5/20/2016)... 20, 2016  VoiceIt is excited to announce ... By working together, VoiceIt and VoicePass ... and VoicePass take slightly different approaches to voice ... security and usability. ... new partnership. "This marketing and technology ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... MONICA, Calif. , June 23, 2016  The Prostate Cancer Foundation ... pioneer increasingly precise treatments and faster cures for prostate cancer. Members of the ... institutions across 15 countries. Read More About the Class ... ... ...
(Date:6/23/2016)... , June 23, 2016   EpiBiome , a ... $1 million in debt financing from Silicon Valley Bank ... automation and to advance its drug development efforts, as ... facility. "SVB has been an incredible strategic ... services a traditional bank would provide," said Dr. ...
(Date:6/23/2016)... ON (PRWEB) , ... June 23, 2016 , ... STACS ... DNA Technical Leader at the Arkansas State Crime Laboratory, has joined STACS DNA as ... the STACS DNA team,” said Jocelyn Tremblay, President and COO of STACS DNA. “In ...
(Date:6/23/2016)... 23, 2016 Apellis Pharmaceuticals, Inc. today ... trials of its complement C3 inhibitor, APL-2. The ... ascending dose studies designed to assess the safety, ... injection in healthy adult volunteers. Forty ... a single dose (ranging from 45 to 1,440mg) ...
Breaking Biology Technology: