Navigation Links
The Forsyth Institute receives Grand Challenges tuberculosis biomarkers grant
Date:2/9/2012

CAMBRIDGE, Mass., − The Forsyth Institute announced today that it will receive a tuberculosis (TB) biomarkers grant through the Bill & Melinda Gates Foundation's Grand Challenges in Global Health program, an initiative which seeks to overcome persistent bottlenecks in creating new tools that can radically improve health in the developing world. Antonio Campos-Neto, MD, PhD, Head of the Global Infectious Disease Research Center at Forsyth will pursue an innovative research project to identify and validate TB biomarkers, titled "Validation of the diagnostic utility of Mtb protein biomarkers found in urine of TB patients".

The Grand Challenges TB biomarkers program provides funding for groundbreaking research into TB biomarkers for the development of a low-cost, simple to use tool that can quickly and accurately diagnose TB in developing countries.

"There is an urgent need to break through barriers in biomarker research in order to develop a highly-sensitive point-of-care diagnostic to improve identification of active TB cases," said Chris Wilson, Director of Global Health Discovery at the Bill & Melinda Gates Foundation. "We hope these innovative ideas lead to effective and affordable TB diagnostics that can make an impact on one of the world's deadliest infectious diseases."

Dr. Campos-Neto's project is one of ten Grand Challenges TB biomarkers grants announced today.

Dr. Campos-Neto is working on the development of an antigen detection assay for the diagnosis of TB based on a single urine sample. His research focuses on the diagnosis of active TB through a technique that could be similar to a simple home-pregnancy test. Current diagnostic tests for TB have several shortcomings. Traditional TB tests focus on the direct identification of the infectious agent in the sputum of patients with active disease, which typically occurs when the patient presents with a persistent cough. These tests have limited sensitivity and are time-consuming, in some cases requiring up to six weeks to collect and examine samples. The test that Dr. Campos-Neto hopes to develop will overcome the challenges of existing tests and will accurately diagnose active TB.

The immediate goal of the project is to validate seven proteins of Mycobacterium tuberculosis (the agent of TB) as biomarkers of active disease. This work will be done in collaboration with Dr. David Duffy, Quanterix Corp, Cambridge, Mass., and Dr. Nira Pollock, Beth Israel Deaconess Medical Center, Boston, Mass.


'/>"/>

Contact: Jennifer Kelly
jkelly@forsyth.org
617-892-8602
Forsyth Institute
Source:Eurekalert

Related biology news :

1. Forsyth scientists trigger cancer-like response from embryonic stem cells
2. Forsyth scientist receives major grant to support rapid, accurate, affordable test for tuberculosis
3. Forsyth scientists suggest linkages between obesity and oral bacterial infection
4. Forsyth receives highly competitive challenge grants
5. Forsyth scientists support the Human Microbiome Project
6. Forsyth team gains new insight on childhood dental disease
7. Wistar Institute researcher receives New Innovator award from NIH
8. Swiss Institute of Bioinformatics celebrates 10th birthday by presenting major gifts to human health
9. Broad Institute awarded major grant to bolster epigenomics research
10. Salk researcher Terry Sejnowski elected to Institute of Medicine
11. EPA teams with National Geographic Society and World Resources Institute to map ecosystem services
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2017)... The research team of The Hong Kong Polytechnic University ... adopting ground breaking 3D fingerprint minutiae recovery and matching technology, pushing ... for use in identification, crime investigation, immigration control, security of access ... ... A research team led by Dr Ajay ...
(Date:3/29/2017)... 29, 2017  higi, the health IT company that ... North America , today announced a Series B ... of EveryMove. The new investment and acquisition accelerates higi,s ... to transform population health activities through the collection and ... higi collects and secures data today on behalf ...
(Date:3/27/2017)... March 27, 2017  Catholic Health Services (CHS) ... Systems Society (HIMSS) Analytics for achieving Stage 6 ... sm . In addition, CHS previously earned a ... using an electronic medical record (EMR). ... level of EMR usage in an outpatient setting.  ...
Breaking Biology News(10 mins):
(Date:5/24/2017)... (PRWEB) , ... May 23, ... ... Northeast's premier provider of high quality relocatable and permanent modular buildings, announced ... visual management tools and modern office design characteristics to help support on-site ...
(Date:5/23/2017)... Canada (PRWEB) , ... May 23, 2017 , ... ... Firmex FileSend, a cloud-based file transfer solution that makes it easy for organizations ... without having to worry about cumbersome FTP software or email file size limitations. ...
(Date:5/23/2017)... ... May 22, 2017 , ... NetDimensions ... in the Aragon Research Globe™ for Corporate Learning, 2017. , Aragon Research defines ... market demand, and effectively perform against those strategies. NetDimensions’ ranking as a Leader ...
(Date:5/23/2017)... ... 23, 2017 , ... Kathy Goin is joining myClin ... brings years of expertise in establishing and leading clinical operations at Sponsors including ... occupational therapist, through a variety of leadership roles in Clinical Operations, to her ...
Breaking Biology Technology: