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The DOE Joint Genome Institute expands capabilities via new partnerships
Date:5/15/2013

E JGI, other large-scale capabilities particularly those that will help link sequence to function will be provided to JGI users in the future," Bristow said.

When the DOE JGI was founded back in 1997 to help accelerate the Human Genome Project (HGP) effort, the partnership consisted of DOE National Laboratory and university partners. After completing the DOE's commitment to the HGP in 2004, the DOE JGI opened its doors as a national user facility advancing the frontiers of genomics for energy and environmental applications. In 2012 alone, the Institute completed over 2,600 projects.

For the first cycle of the ETOP, the DOE JGI has selected these six new partnerships:

  • "Single cell approaches to metagenomics," proposed by Stephen Quake of Stanford University. This technology could make it easier to isolate single cells of interest from complex environmental samples.

  • "Accurate gene synthesis with tag-directed retrieval of sequence-verified DNA molecules," proposed by Jay Shendure of the University of Washington. This technology could streamline the DNA synthesis pipeline and increase the output.

  • "High-throughput sorting of microbial cells with specific functional traits for single cell genomics by combining labeling with heavy water, Raman microspectroscopy, microfluidics and flow cytometry," proposed by Roman Stocker of MIT and Michael Wagner of the University of Vienna (Austria). This technology could accelerate the functional characterization of genes from metagenomic sequencing experiments, one of DOE JGI's highest priorities.

  • "Generation of high-quality genomic DNA from plants and other organisms, large insert libraries and high-quality physical maps for improved physical map and sequence level-assemblies," proposed by Rod Wing of the Arizona Genomics Institute (AGI). This technology could make considerably easier the isolation of DNA from plants in amounts and quality that can be more effectively sequen
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Contact: David Gilbert
degilbert@lbl.gov
DOE/Joint Genome Institute
Source:Eurekalert

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