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The Chemistry of Fear: A new video from the American Chemical Society

With Halloween just a few days away, millions are flocking to horror films and haunted houses for their annual dose of terror. The latest video from the American Chemical Society's (ACS) Bytesize Science series uncovers the chemistry behind the spine-tingling sense of fear. The episode is available now at

"Fear is the expectation or the anticipation of possible harm We know that the body is highly sensitive to the possibility of threat, so there are multiple pathways that bring that fear information into the brain," explains Abigail Marsh, Ph.D., associate professor of psychology at Georgetown University. Marsh's research focuses on the neuroscience of fear and empathy in psychopaths, among other topics. In the video, she highlights the key brain chemicals and hormones involved in fear and the accompanying fight or flight response.

Marsh explains that the amygdala, an evolutionarily ancient part of the human brain, is the most important structure in the fear response. In a bonus video also available at, Marsh tells the story of "SM," a woman without a functional amygdala who is quite literally fearless.


Contact: Michael Bernstein
American Chemical Society

Page: 1

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